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PERSON: Spinalized animals have the potential to generate well organized bilateral locomotion movements of the hindlimbs |
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PERSON: Half-Center Hypothesis Spinally transected cats Alternating flexion/extension of hindlimbs Activity persisted with deafferentation Proposed flexor/extensor muscle controlled by two systems of neurons that are mutually ihibitory |
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ASIA: Complete: No motor or sensory function is preserved in the sacral segments S4-5 |
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ASIA: Incomplete: Sensory but not motor function i preserved below the neurological level and includes the sacral segments S4-5 |
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ASIA: Incomplete: Motor function is preserved below the neurological level and more than half of key muscles below the neurological level have a muscle grade less than 3. |
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ASIA: Motor function is preserved below the neurological level and at least half of the key muscles below the neurological level have a muscle grade of 3 or more. |
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ASIA: Motor and sensory functions are normal |
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Is there one area of the CNS that controls locomotion? |
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Definition
No, its widely distributed |
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The spinal cord caudal to the injury has autonomous intrinsic capabilities to generate locomotor movements, when ___ are stimulated or ___ agents are applied. |
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Definition
Sensory Afferents Pharmacological |
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Term
Spinal cord can operate in isolation from ___ commands and ___ feedback. |
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Name 2 interactions that work with CPGs to initiate, stop, or modulate locomotion |
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Descending Commands Sensory Information |
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If there is a change in descending control or elimination of afferent feedback then ___ must occur. This concept suggests ___ can occur. |
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Barbeau and Rossignol - ___ even in the adult cat. The adult rate does not recover spontaneous locomotion after complete injury. |
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Studies show that training starts when? for how long? How much? |
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Definition
2-3 days after injury for 4-6 weeks Daily |
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Animal models of SCI include: (2) |
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Definition
1. Contusion 2. Complete Transection |
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Term
Where some pathways are still intact |
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Do we have evidence that a human with a complete SCI can regain independent locomotion after the injury with training? |
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Translation from the treadmill to functional ambulation is what? |
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Do we have evidence that a human with an incomplete SCI can regain independent locomotion after the injury with training? |
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Studies focus on the importance of loading the extremity and achieving hip extension in __ |
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Do we have evidence that training a patient to stand and training a patient to walk are different tasks and require training of each task? |
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