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History of developmental biolo
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19
Biology
Undergraduate 4
02/25/2009

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Term
Preformation
Definition
1880s - believed the body form is already present and merely increases in size
Term
Leuwenhook
Definition
discovered the sperm cell
Term
Casper Wolf
Definition
developed the theory of generation - organis and tissues arise from undifferentiated tissues
Term
Schlediden and Schwann
Definition
believe all living things consisted of cells which arise from other cells
Term
August Weismann
Definition
distinguished between germ and somatic cells and suggested that segregates of embryos --> determinants
Term
Epigenesis
Definition
19th century - belief that one cell gives rise to all others
Term
Aristotle
Definition
4th century = studied bird eggs at different stages and believed the male seed provided the structure and the female the rest
Term
William Harvey
Definition
1650 - ex ovo omnia
Term
Christian Pander
Definition
1820 - discovered germ layers and induction
Term
Induction
Definition
formation of specific tissues from germ layers
Term
Ectoderm
Definition
germ layer that forms skin and nerves
Term
Endoderm
Definition
germ layer that forms gut, liver, and lung tissue
Term
Mesoderm
Definition
germ layer that forms skeleton, muscle, kidney, heart, and reproductive tissues
Term
Karl Ernst von Baer
Definition
early 1800s - discovered the mammalian ovum and notocord
- believed embryonic forms of most animals are similar
- general structures form first than specialize
Term
Carles Darwin
Definition
1990s - community of embryonic sturctures reveals a community of descent
Term
Gregor Mendel
Definition
Studied genetic inheritance
Term
1900s
Definition
chromosomes recognized as units
cell lineages established
cell migration traced from ebmbryo to adult
Term
Hans Spemann and Hilde Mangold
Definition
1920s - normal gastrulation in ambihibians begins at the blastopore of the blastula and create a cavity called the archenteron
-experiment took cells of the blastopore from one embryo and grafted them onto another --> formation of archenteron and an organism that looks like a siamese twin
Term
Watson and Crick
Definition
1950s - reveled DNA structure and molecular mechanis
Environment --> DNA --> RNA --> Protein --> Development
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