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Actively produce the extracellular matrix (ECM); prominent nucleoli, basophilic cytoplasm |
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Are involved in the maintenance of the ECM and can differentiat into other types of CT cells |
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-Separates the epithelium from the CT -Type IV collagen mainly -Epithelial cells adhere to this via junctional complexes |
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-"Fried egg" shape -basophilic cytoplasmic granules -releases heparin, histamine, serotonin -defence against allergic rx, degranulate, >vascular perm. |
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Unilocular: -"signet ring" -sg lipid droplet found in grps -E reserve and shock abs. Multilocular: -brown fat -multiple lipid droplets, very vascular w/ lots of mito. -heat production "hibernation gland" |
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-elastin protein -mol. crosslink and asssemble into fibres/sheets -relaxed=random coil -stretches and recoils -pinna ear, vocal chords, lungs, elastic lig'ts, dermis, aorta -provides tensile strength |
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-provides framework in lymph nodes, liver, spleen, blood vessels, nerves -individual fibrils of type III collagen |
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Fibrous adhesive proteins |
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-Bind to cell mems, collagen, and elastin -Fibronectin and laminin proteins |
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-Pigment producing cells -From neural crest ectoderm -protect mitotic cells from UV light |
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-Large cells -Defense -Mononuclear phagocyte system -Enter CT space by diapedesis |
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-Sensitised form of blood lymphocyte -Antibody production -Gut, lung tissue, skin... -Clock-faced chromatin in nucleus, basophilic cytoplasm |
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-Fibres (collagen, reticular, eleastic) -Amphorous ground substance (GAGs, proteoglycans, glycoproteins) |
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-Embryonic connective tissue -Cells long, slender processes, and initially no fibres |
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-Embryonic connective tissue -Umbilical cord, wattle and comb of chicken -Few stellate fibroblasts, mainly amphorus ground substance, few collagen fibres |
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-Manny scattered cells, abundant ground substance, loose random network of CT fibres, blood vessels and nerves -Provides support and vascular supply to surface epithelia, tissue repair, and defense activities -Gut lining, duodenum |
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-Fibres more abundant, irregularly arranged, widespread -Skin dermis |
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-Fibre bundles parallel to give max strength -Interspersed w/ collagen to prevent over stretching -Tendons, lig'ts |
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-Reticular fibres predominate -Where structural support is needed, but not brute strength -Lymph nodes, spleen, bone marrow |
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-"Chicken wire" -Supported by collagen and reticular fibres -Some fibrocytes, mast cells, and sparce amphorous ground substance |
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-Fibroblasts and fibrocytes -Macrophages -Mast cells -Chromatophores -Adipocytes |
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-Plasma cells -Eosinophils, neutrophils, lymphocytes |
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