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Histology
Willard Morrow
11
Medical
Professional
01/12/2012

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Term
What are some of the functions of the cytoskeleton
Definition
structural support for the plasma membrane and cell organelles, intracellular movement/transport of substances, cell locomotion, mm contraction
Term
What are the three main elements of the cytoskeleton
Definition
microfilaments, intermediate filaments, and microtubules
Term
If you have a cut and you need wound contraction to occur during the healing which element of the cytoskeleton would be the most helpful
Definition
microfilaments. These also are important to maintaining cell shape, and facilitating shape changes during movement.
Term
This is beneath the plasma membrane, and forms the support meshwork that prevents the cell from deformation.
Definition
actin
Term
Explain what myosin do in muscle contraction.
Definition
They form cross-bridges with actin to produce the contractile movement of our muscles. This also requires Ca and ATP.
Term
What are the five different classes of intermediate filaments and where are they found.
Definition
cytokeratin-epithelial, vimentin-mesodermal cells (endothelial, smooth muscle, neuroectodermal) desmin-muscle, neurofilament proteins-neurons, GFAP- glial fibrillary acidic protein
Term
What produces GFAP
Definition
astrocytes
Term
What are microtubules made up of
Definition
2 types of globular protein subunits (alpha and beta tubulin) arranged in a coiled spiral pattern.
Term
What are the two proteins that attach to microtubules to allow for movement in the cytoplasm
Definition
dynein and kynesin
Term
What do microtubules do during cell division
Definition
they produce the cell spindle during cell division which functions to pull the chromosomes apart.
Term
What's an arrangement of microtubules that is 9 + 2
Definition
axoneme. These grow from the basal body and are derived from modified centriole.
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