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Histology
Adipose, Cartilage, Bone, Blood
49
Biology
Undergraduate 4
10/10/2011

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Term
Hormone sensitive Lipase

(HSL)

 

Definition
Helps generate energy by breaking down fat, it is stimulated by the addtion of norepinepherine in the system.
Term
Chylomicra/ VLDL
Definition
Chylomicra and VLDL are responsible for taking the white fat and transporting it in the blood. For Chylomicra, it is in the intestines, for VLDL, it is in the liver. This process of transportation is induced by insulin. Once this fat is transported, it is broken down by HSL (hormone sensitive lipase) that is stimulated by norepinepherine.
Term
Brown Fat thermogenin
Definition
Called UCP-1, it helps uncouple a proton from ATP production, hence energy goes off as heat.
Term
Tryglyceride
Definition
Glycerol + FFA
Term
Hyaline Cartilage
Definition
Most common type of cartilage, found in joints, respiratory system.
Term
Elastic Cartilage
Definition
Second most common, found in ears, head
Term
Chondroblasts
Definition
Cells that make cartilage
Term
Apositional Growht
Definition
Growth of bone or cartilage that stuff is being added, such as pouring concrete into a drive way
Term
Intersissional Growth
Definition
Growht that happens from the center of the bone or the cartilage then it expands.
Term
Epiphysis
Definition
Head of long bone
Term
diathesis
Definition
shaft of long bone
Term
Dense(compact) bone
Definition
known as cortex bone also. Dense rigid outer shell.
Term
Cancellous (spongy)
Definition
thin interconnecting narrow bone trabeculae.
Term
metaphysis with epiphyseal plate.
Definition
The metaphysis is the wider portion of a long bone adjacent to the epiphyseal plate.[1] It is this part of the bone that grows during childhood; as it grows, it ossifies near the diaphysis and the epiphyses. At roughly 18 to 25 years of age, the metaphysis stops growing altogether and completely ossifies into solid bone.

Epiphyseal plates ("growth plates") are located in the metaphysis[citation needed] and are responsible for growth in the length of the bone.
Term
Compostion of bone
Definition
35% organic matter, 65% calcium salts.
Term
Decalcified preparation of bone
Definition
Chelators used to soak up all of the calicum salts, which leave behind the organic matrix and cells. You cannot observe the canniliculi.
Term
Ground section of Bone
Definition
Ground really thin and this produces alot of heat, destroys all of the organic material and it is left only with the inorgaincs, you cant see matrix or cells but you can see the caniliculi and the lacunae.
Term
Howships lacunae
Definition
caused by osteoclasts, little holes in the bone.
Term
canaliculi
Definition
microscopic canals between lacunae of osefied bone.
Term
Osteoblasts
Definition
cells that lay down bone.
Term
osteocytes
Definition
When osteoblasts become trapped in the matrix they secrete, they become osteocytes. Osteocytes are networked to each other via long cytoplasmic extensions that occupy tiny canals called canaliculi, which are used for exchange of nutrients and waste through gap junctions. The space that an osteocyte occupies is called a lacuna (Latin for a pit).
Term
osteoclast
Definition
cells that break down bone, can be seen doing their depression on the bone, the reason they do it is to release needed calcium into the system. Acts like a calcium bank.
Term
Carbobic anhydrase
Definition
takes carbonic acid and it converts it into HCL which osteoclasts use to break down bone.
Term
Intramembrenous growth
Definition
Flat bones with a layer of osteoblast: no cartilage
Term
endochondral growht
Definition
long and short bone growth.
Term
cartilage model
Definition
The cartilage model will grow in length by continuous cell division of chondrocytes, which is accompanied by further secretion of extracellular matrix. This is called interstitial growth. The process of appositional growth occurs when the cartilage model also grows in thickness due to the addition of more extracellular matrix on the peripheral cartilage surface, which is accompanied by new chondroblasts that develop from the perichondrium.
Term
Primary (Woven bone)
Definition
first bone laid down in embryo or after broken bone. then it becomes secondary bone
Term
Haversian systems (osteon)
Definition
most complicated of secondary bone. Lamellar bone. Contains central canal wich carries blood vessels, nerves.
Term
Scury
Definition
Dietary defect, a bone disease, poor collagen formation
Term
Rickets
Definition
Poorly mineralized bone in children
Term
Osteomalacia
Definition
Poorly mineralized bone in adults, but number of holes not abnormal
Term
Osteoporosis
Definition
Bone disease becuase of hormonal imbalance. Creates brittle porous bone, especially in women after they have gone thru menopause. Decline in estrogen levels. net effect f osteoclastic ostelolysis overridin osteoblastic osteogenesis.
Term
CBFa-1 knockouts
Definition
embryo unable to form bone.
Term
alazirin red
Definition
stain used to stain bone and cartilage. Bone stains pink, cartilage stains blue.
Term
Cleidocranial Dysplasia
Definition
autosomal dominant gene (runx2)
Term
erythrocytes
Definition
red blood cells, 99% of all cells.
Term
Leukocytes
Definition
white blood cells, Less than one percent in buffy coat after centrifugation.
Term
hematocrit
Definition
blood volume taken up by erythrocytes.
40-45&
Term
platelets
Definition
small irregular shaped cell fragments that are made after the breakdown of megakaryocytes
Term
RBC
Definition
Bi-concave discs on the order of 7.5 micro meters. Mature cells are anucleated with very little organelles but they contain large amouts of hemoglobin.
Term
hemoglobin
Definition
gas carrying protein found in RBC, can irreversibly bind O2, CO2, NO but binds irreversably to CO. made up of two pairs of goblin proteins. Alpha goblin and 2 beta goblins. each goblin associated with iron containing heme group that binds gas.
Term
sickle cell anemia
Definition
disease where a substitution in beta globulin aa happenns and it makes it polymerize.
Term
Leukocytes
Definition
White blood cells.
Term
Granulocytes
Definition
Granulocytes are a category of white blood cells characterized by the presence of granules in their cytoplasm.[1] They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments
Term
epymysium
Definition
CT sheat around entire muscle
Term
perymysium
Definition
CT around bundle of muscle cells
Term
endomysium
Definition
CT around a single myofiber(Muscle cell)
Term
skeletal muscle
Definition
multinucleated cells; highly arranged bundles of cytoskeletal elements (thick and thin filaments)
Term
myofiblrl
Definition
sarcomeres that line up to give striations.
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