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Histology - Female Repro
Complete
64
Medical
Undergraduate 1
10/06/2008

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Cards

Term
Follicles and interstitial connective tissue make up what part of the ovary?
Definition
the cortex
Term
What is the name for the dense collagenous connective tissue that surrounds the ovary?
Definition
the tunica albuginea
Term
What is the name for the specialized endocrine sac where oocytes mature?
Definition
the follicle
Term
Describe the primordial follicle.
Definition
oocyte in basal lamina surrounded by granulosa cells, the oocyte is in its first mietotic div.
Term
What changes occur that convert a primordial follicle into a primary oocyte?
Definition
The oocyte and its nucleus enlarges, flattend granulosa cells become cuboidal and proliferate to become stratified, the zona pallucida is formed by the oocyte and the granulosa cells, the interstitial cells surrounding the granulosa become the theca folliculi
Term
Describe the two layes of the theca folliculi.
Definition
The inner layer secretes androgen which is converted to estrogen by the granulosa cells, and the outer layer, the theca externa, is made up of connective tissue and smooth muscle
Term
Describe secondary follicles.
Definition
a fluid filled space appears (the antrum), granulosa cells secret liquor folliculi, granulosa cells proliferate to form the cumulus oophorus, theca cells proliferate
Term
What does liquor folliculi contain?
Definition
glycosaminoglycans, steroid binding proteins and steroids
Term
What is another name for the mature follicle?
Definition
the graffian follicle
Term
Describe the mature follicle
Definition
The follicle is large and bulges from the cortex, the cumulus oophorus shrinks, the corona radiata surrounds the the ovum
Term
About how many days are required for a primordial cell to mature into a graffian follicle?
Definition
90
Term
What causes ovulation?
Definition
a surge in LH
Term
Where does LH come from?
Definition
the anterior pituitary
Term
Where does the ovum enter the oviduct?
Definition
at the infundibulum
Term
When does the ovum complete its first meiotic division?
Definition
just before ovulation
Term
At what stage of the second meiotic division does the ovum arrest in prior to fertilization?
Definition
metaphase
Term
At what stage of follicular development can atresia occur?
Definition
any stage
Term
What cells remove the debri left over after atresia?
Definition
macrophages
Term
What cells form a scar where the follicle underwent atresia?
Definition
fibroblasts
Term
What two factors allow for the continued growth of the follicle?
Definition
Follicular Stimulating hormone and estrogen
Term
Which hormone stimulates theca interna cells to produce androgens?
Definition
lutenizing hormone (LH)
Term
Which cells convert LH to estrogen?
Definition
granulosa cells
Term
How does estrogen affect granulosa cells and the follicle
Definition
It stimulates granulosa cells to proliferate and the follicle to continue developing
Term
What is the name of the temporary endocrine gland created by the follicles after ovulation?
Definition
the corpus luteum
Term
What do granulosa lutein cells produce?
Definition
progesterone and estrogen
Term
In the absense of fertilization, what does the corpus luteum become?
Definition
the corpus ablicans
Term
What happens to the corpus luteum if fertilization occurs?
Definition
trophoblastic cells from the implanted embryo produce human chorionic gonadotropin which promote the growth of the corpus luteum and allow it to produce increased amounts of progesterone
Term
Describe the medulla of the ovary.
Definition
it contains blood vessels and connective tissue
Term
What are the four layers of the oviduct?
Definition
1) infundibulum 2) ampulla 3) isthmus 4) intramural
Term
What are the two types of cells in the mucosa?
Definition
ciliated and secretory (peg) cells
Term
What do the secretion of peg cells promote?
Definition
capacitation (activation) of spermatozoa, and nourishment of the ovum
Term
How is the infundibulum brought closer to the ovary during ovulation?
Definition
muscles contract and large blood vessels in the fimbrea engorge like erectile tissue
Term
Name the four parts of the uterus
Definition
the fundus, body, isthmus, and cervix
Term
Where does implantation usually occur?
Definition
the fundus
Term
What is the mucosa called in the uterus?
Definition
endometrium
Term
What is the muscularis called in the uterus?
Definition
myometrium
Term
What is the serosa called in the uterus?
Definition
perimetrium
Term
What are the two layers of the endometrium?
Definition
lamina functionalis and lamina basalis
Term
Which layer of the endometrium is shed during menstruation?
Definition
lamina functionalis
Term
What do the simple tubular glands of the endometrium secrete?
Definition
a complex mixture of glycoproteins that serve to nourish the embryo prior to implantation
Term
What are the two arteries from the arcuate arteries that supply the endometrium?
Definition
basal (straight) arteries and spiral (coiled) arteries
Term
Which layer of the endometrium is supplied by the basal arteries?
Definition
lamina functionalis
Term
Which layer of the endometrium is supplied by the spiral arteries?
Definition
lamina basalis
Term
What do spiral arteries become if implantation occurs?
Definition
placental arteries
Term
What are the three phases of the menstrual cycle?
Definition
proliferative, secretory (luteal), menstrual
Term
Describe the proliferative phase of the menstrual cycle.
Definition
At the beginning of the phase, only the lamina basalis remains, glands and surface epithelium regenerate
Term
Describe the secretory phase of the menstrual cycle.
Definition
progesterone from the corpus luteum triggers uterine glands begin secretion
Term
Describe the menstrual phase of the menstrual cycle.
Definition
The decrease in progesteron and estrogen cause the spiral arteries to contrict and the lamina functionalis becomes ischemic and necrotic.
Term
What is the squamocolumnar junction?
Definition
Where the two types of epithelium of the ectocervix and the endocervix meet.
Term
Before puberty, what type of epithelium is the ectocervix?
Definition
stratified squamous non keratinzed epi.
Term
Before puberty, what type of epithelium is the endocervix?
Definition
tall columnar mucous secreting
Term
What happens to the epithelium of the endocervix after puberty?
Definition
it becomes stratified squamous epi. In a region called the transformation zone
Term
What is a nabothian cyst?
Definition
When a duct of the glands of the cervix become blocked
Term
What happens to the secretions of the cervix before and after pregnancy?
Definition
They are watery at first, then they are viscous mucous to prevent microorganismns from entering
Term
What is the composition of the cervix?
Definition
85% dense connective tissue and little smooth muscle
Term
What does the vagina synthesize under estrogen stimulation?
Definition
glycogen, which is deposited in the lumen of the vagina
Term
What happens to the glycogen in the vagina?
Definition
bacteria metabolize it and produce lactic acid which lowers the pH
Term
Do men have mammary glands?
Definition
yes
Term
What helps the mammary glands to undergo rapid growth at puberty?
Definition
estrogen
Term
What causes full differentation of the mammary glands?
Definition
pregnancy
Term
What happens to the mammary glands after menopause?
Definition
they regress
Term
Describe a resting mammary gland.
Definition
the tubuloalveolar glands is composed of ducts which form lactiferous ducts which empty into a lactiferous sinus prior to exiting the nipple
Term
Describe an active mammary gland.
Definition
pregnacy hormones stimulate the elogation of the ducts and the growth of the alveoli
Term
What occurs when milk is triggered by suckling?
Definition
oxytocin is released from the neurohypophysis which cause the release of milk
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