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Histology Exam 1 - Neurobiology
Neurobiology notes from Walrond and Stewart
33
Histology
Professional
09/17/2011

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Term
nerve cell
Definition
genetic, anatomic, and functional unit of the nervous system
Term
3 functional regions of a neuron
Definition
input region, conductile region, and output region
Term
input region
Definition
region of neuron that contains passive membrane
Term
conductile region
Definition
region of a neuron that contains voltage-gated channels
Term
output region
Definition
region of a neuron from which neurotransmitter is released
Term
potential decay
Definition
amplitude of an action potential decays with distance traveled along the conductile region of a neuron in a membrane lacking voltage-gated channels
Term
passive membrane
Definition
neuronal membrane lacking voltage-gated ion channels; present in neuronal input regions
Term
action potential propagation
Definition
sequential opening of voltage-gated Na+ channels followed by opening of voltage-gated K+ channels
Term
myelin sheath
Definition
increases conductivity along a neuron
Term
nodes of Ranvier
Definition
gaps between myelin sheaths in which voltage-gated channels are concentrated
Term
depolarization
Definition
event that opens voltage gated Na+ channels
Term
presynaptic regions
Definition
constitute release of neurotransmitter
Term
postsynaptic regions
Definition
constitute transduction of chemical (neurotransmitters) to electrical signals
Term
synaptic vesicles
Definition
carry Ca+ ions via exocytosis into synaptic cleft
Term
small molecule transmitters
Definition
acetylcholine, glutamate, GABA, glycine, serotonin, the catecholamines, and the purines
Term
main subsets of neurotransmitters
Definition
small molecule transmitters and peptides
Term
axon terminal
Definition
portion of neuron in which small molecule transmitters are created and packaged
Term
peptide neurotransmitters
Definition
small, neuromodulatory proteins; over 50 identified; many act as hormones elsewhere; function through second messengers
Term
ligand-gated ion channels
Definition
opened by neurotransmitters
Term
cation channel
Definition
excitatory ligand-gated ion channel
Term
anion channel
Definition
inhibitory ligand-gated ion channel
Term
excitatory post synaptic potential (EPSP)
Definition
<1 mv; summate with IPSPs to determine if a trigger zone reaches threshold level
Term
triggering an action potential
Definition
hundreds of potentials are required
Term
spatial summation
Definition
addition of potentials arriving from different regions
Term
temporal summation
Definition
addition of potentials within the same time window
Term
glial cells
Definition
support cells of the nervous system
Term
neuropile
Definition
background matter in nervous tissue slides (cross sections of neurons, etc.)
Term
nissel substance
Definition
intracellular components of neuronal cell bodies
Term
mylenated neurons
Definition
increased conduction; faster reactions; "superficial pain"
Term
unmylenated neurons
Definition
reduced conduction; slower reaction; "deep pain"
Term
oligodendrocyte
Definition
creates mylen sheath in CNS
Term
schwann cell
Definition
creates mylen sheath in PNS
Term
single nucleus in a PNS nerve
Definition
could belong to a schwann cell, an endothelial cell, or a CT cell; NOT THE NUCLEUS OF A NEURONAL CELL BODY
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