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function of connective tissue |
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Definition
- transport nutrients, o2, waste and metabolites - immunological surveillance/defense - mechanical support - growth and repair - energy storage and thermoregulation - hematopoiesis |
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- cells - extracellular matrix |
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- fibroblasts - macrophages - mast cells - plasma cells - adipocytes |
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- secrete all components of extracellular matrix - repairs and regenerates CT following damage |
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- engulf/destroy bacteria through phagocytosis - remove necrotic debris - participate in immune and inflammatory response - number increases in CT following wound/inflammation |
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- participate in allergic reaction - release histamine and heparin after allergen binding - central role in asthma, eczema, itch, allergic rhinitis and allergic conjunctivitis |
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- vasodilator - anticoagulant - both proteins |
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- synthesize/secrete abys - function in immune response to destroy bacteria and other antigens |
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- unilocular - stores fat/lipids - incorporate into loose CT to form fat |
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- fibers - ground substance |
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fibers in Extracellular Matrix |
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- collagen - elastic fibers |
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- major insoluble protein in CT - most abundant protein in body - fibrillar and basement membrane - types I-IV |
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- provides tissues with tensile strength - types I-III |
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- fibrillar collagen - all CT in oral cavity except enamel - Sharpey's fibers |
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- type I collagen - bundles of fibrillar collagens inserted into surface of mineralized tissues (bone/cementum) - attached to periosteum and periodontal ligament |
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- fibrillar collagen - in cartilage |
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- fibrillar collagen - forms reticular fibers |
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basement membrane collagens |
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- allow tissues to go back to normal shape after stretching/distortion - consist of microfilaments and elastin |
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- protein and sugar (glycoamino- and proteo- glycans) - glycoproteins - water |
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- most abundant CT in embryo - very little in adult - closest related to tooth pulp in adult |
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- loose - adipose - reticular - dense irregular - dense regular - cartilage - elastic - bone |
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- located directly under epithelium w/basal lamina in between - lots of cells, blood vessels, nerves and glands |
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- loose connective tissue in GI tract and oral cavity |
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- storage of energy in form of lipids - insulates against heat loss - space filler btwn organs or tissue layers of organs - cushioning soles of feet, orbits of eyes, and around kidneys |
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- consists of reticular fiber network - made of collagen type II - provides delicate structural support - found under basal lamina, around blood vessels and nerves and in lymph organs |
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- lost of large collagen fibers running in all directions - few cells - great tensile strength - forms capsules around organs |
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- ordered arrangement of collagen type I fibers and fibroblasts - mainly in tendons and ligaments - great tensile strength in direction of fibers |
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- firm, non-calcified CT - shock-absorbing, sliding area for joints - facilitates bone movement - development/growth of long bones - not vascularized or innervated - contain chondrocytes |
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- mitotic cells allowing growth - can multiply and secrete cartilage matrix - slows in adults and eventually die to create calcification of the cartilage |
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- most widely distributed in embryo/adult - collagen type II fibers - forms fetal skeleton - epiphyseal plates - articular cartilage covers articular surfaces of adult bone |
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- collagen type II fibers and elastic fibers - found in areas that need to bend or recoil - external ears and epiglottis |
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- areas subject to both compression and tension - combo of cartilage and collagen type II - type I runs btwn chondrocytes of cartilage |
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- type I collagen fibers and lots of elastic fibers - allow organs to stretch in several directions then recoil - found in aorta |
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