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abundant RER in neurons in cell body and dendrites- not axons |
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cell body- nucleus/organelles axon-long process reach distant cells- output dendrites-short processes for input synapses-special cell junctions |
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single axon-lots dendrites-MOTOR neurons |
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pseudounipolar- located in dorsal root ganglia: one to CNS, one to periphery |
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bipolar- mostly communicating-connect two groups of neurons |
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ionic gradient across membrane firing with depolarization -rest -70mv depolar from + ion entering cell membrane and make less negative
hyperpolarization makes membrane potential more negative -happens when negative ions ENTER
outward current + ions causes hyperpolarization (or cl- enter) |
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ligand gated-chem transmitt substance voltage gated- respond to depolarization, all or none response large signal and Na and K channels open lead to explos chg in act potent |
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Definition
terminal end of axon swollen form bouton
-close to target cell with 20nm synaptic cleft gap
-neurosecretory granules released in cleft and bind to postsynaptic membrane and cause chg in act potent of postsynaptic membrane excit or inhib |
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depolarization- bind to ligand gated receptor Na channel open lead to act potent
hyperpolarization-bind ligand gated recept, sm - ions inhibit neuron lead to depression (gamma amino butyric acid and glycine are inhibitor neurotransmitters) |
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axosomatic/axodendritic(most common)/axoaxonal (excit or inhibit) |
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oligodendrocytes CNS-multiple axon schwann in PNS- one axon
insulate nerve- speed nerve transmisison- prevent leak of act potent
spiral layer cell membrane wrappped round axon -bound by adhes molecules |
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Term
special adhesion molecules myelin |
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Definition
PO protein in PNS Proteolipid proteins in CNS- bind to exoplasmic sufaces of myelin membrane- myelin basic protein to cytoplasmic surfaces |
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