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Histamine, Serotonin, Antagonists
n/a
20
Medical
Graduate
09/23/2011

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Cards

Term
diphenhydramine
Definition
sedation (H1 antagonist)
Term
tripelennamine
Definition
moderate sedation, OTC sleep aid (H1 antagonist)
Term
cyclizine
Definition
anti-motion sickness (H1 antagonist)
Term
promethazine
Definition
sedation, anti-emetic (H1 antagonist)
Term
chlorpheniramine
Definition
less sedation, cold meds (H1 antagonist)
Term
loratidine
Definition
no sedation, don't cross BBB, $$, longer duration (H1 antagonist)
Term
fexofenadine
Definition
no sedation, don't cross BBB, $$, longer duration (H1 antagonist)
Term
azelastine
Definition
no sedation,allergic rhinitis, allergic conjunctivitis (H1 antagonist)
Term
famotidine
Definition
block gastric acid secretion (H2 antagonist)
Term
nizatidine
Definition
block gastric acid secretion (H2 antagonist)
Term
cimetidine
Definition
block gastric acid secretion, adverse: antiandrogen, inhibition of P450s (H2 antagonist)
Term
ranitidine
Definition
block gastric acid secretion, adverse: liver toxicity (H2 antagonist)
Term
cyproheptadine
Definition
anti-his & anti-serotinergic, for skin(hives)-antiH1, diarrhea (5HT2), sedation & anti-muscurinic effects (serotonin antagonist)
Term
ketanserin
Definition
antihypertensive, antagonizes platelet aggregation (serotonin antagonist)
Term
ondansetron
Definition
5HT3 prevents N/V assoc w/ radio/chemotherapy (serotonin antagonist)
Term
ergotamine
Definition
partial agonist at all 5HT1,2, antag/agonist of adrenergic, use during migraine (ergot alkaloid)
Term
methysergide
Definition
agonist all 5HT, antagonist 5HT2, prophylaxis only (ergot alkaloid)
Term
triptans
Definition
very selective 5HT1B,D agonists, effective for acute migraine (ergot alkaloid)
Term
ergonovine
Definition
sustain uterine stim for post-partum hemorrhage (ergot alkaloid)
Term
bromocriptine
Definition
D2 agonist, decrease prolactin secretion from pituitary, for hyperprolactinemia (ergot alkaloid)
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