Term
Scopolamine, Diphenydramine, Dimenhydrinate, Meclizine, Promethazine |
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Definition
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Term
Paroxetine, Amitryptyline |
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Definition
CI - concurrent MAO-i use |
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Term
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Definition
Common ADR - pancreatitis |
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Term
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Definition
Common ADR - QT Prolongation |
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Term
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Definition
CI - Concurrent use of Apomorphine |
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Term
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Definition
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Term
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Definition
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Term
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Definition
Indication - CHF, A fib/flutter |
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Term
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Definition
Toxicity - gastric ulceration, bleeding, hyperventilation, tinnitus (damage to CN 8) |
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Term
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Definition
MOA - Inhibit platelet aggregation by irreversibly blocking ADP receptors. Inhibit fibrinogen binding by preventing glycoprotein IIb/IIIa expression. |
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Term
Atorvastation, Simvastatin, Pravastatin |
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Definition
Common ADR - rhabdomyolysis, tendon rupture, hepatotoxicity |
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Term
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Definition
ADR - severe hypotension, METHEMOGLOBINEMIA |
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Term
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Definition
ADR - pulmonary fibrosis, hepatotoxicity, hypothyroidism/hyperthyroidism (Recall - Drug is 40% iodine by wgt, so it's thyroid effects are significant.) |
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Term
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Definition
Indication - Orthostatic Hypotension |
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Term
Citalopram, Fluoxetine, Sertaline, Paroxetine |
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Definition
ADR - Serotonin Syndrome (ass w/ muscle rigidity, hyperthermia, CV instability, flushing, diarrhea, seizures) |
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Term
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Definition
Toxicity - 3 C's = coma, cardiac arrythmia, convulsions |
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Term
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Definition
Indication - depression, smoking cessation |
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Term
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Definition
ADR - PRIAPISM, sedation, nausea, postural hypotension |
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Term
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Definition
Side Effect (often beneficial) - INC appetite, wgt gain |
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Term
Alprazolam, Diazepam, Lorazepam, Clonazepam |
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Definition
2x - 4x INC in risk for FALLS. Related to dose and postural sway. |
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Term
Risperisone, Aripiprazole, Quetiapine, Olanzapine, Haloperidol |
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Definition
Black Box Warning for FALLS when used in Dementia Pt |
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Term
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Definition
ADR - significant extrapyramidal sx, such as dystonia, akinesia, restlessness, and tardive dyskinesia |
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Term
Rosiglitazone, Pioglitazone |
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Definition
MOA- INC insulin sensitivity in peripheral tissues by binding PPAR-gamma nuclear transcription regulator |
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Term
Rosiglitazone, Pioglitazone |
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Definition
CI - CHF Class III/IV, liver impairment |
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Term
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Definition
Indications - DM Type I, DM Type II |
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Term
Glipizide, Glyburide, Glimepriride, Stigliptin |
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Definition
MOA - INC insulin production by closing K+ channels in beta cell membrane. |
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Term
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Definition
1st line anti-HTN for elderly |
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Term
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Definition
Caution - Negatively Ionotropic - Use with caution in elderly patient with conduction abnormality |
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Term
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Definition
Preferentially used in HTN pt with co-morbid conditions such as DM, CHF, LVH, and renal insufficiency |
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Term
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Definition
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Term
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Definition
ADR - Hypokalemia, Hyponatremia, Hyperuricemia, Dehydration |
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Term
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Definition
MOA - Block voltage-dependent L-type Ca++ channels |
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Term
Oxybutynin, Tolterodine, Darifenacin |
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Definition
Indication - Overactive Bladder |
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Term
Doxazosin, Terazosin, Tamsulosin, Finasteride |
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Definition
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Term
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Definition
MOA - 5 -alpha-reductase inhibitor DEC the conversion of Test --> DHT |
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Term
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Definition
ADR - leukopenia, neutropenia |
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Term
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Definition
Potentiated by HTN medication |
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Term
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Definition
ADR - DEC in libido, DEC in ejaculate, Impotence |
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Term
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Definition
Cholinesterase inhibitor that does NOT interact with drugs that alter activity P450 dependent enzymes |
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Term
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Definition
Cholinesterase inhibitors that are substrates for P450 and can alter activity of P450 enzymes. |
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Term
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Definition
MOA - Block NMDA ion channels to limits Ca++ influx into neuron |
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Term
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Definition
ADR - INC incidence of C. diff colitis and diarrhea, LOW B-12 |
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Term
Alenodronate, Risedronate, Ibandronate |
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Definition
ADR - esophagitis, eophageal ulcers |
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Term
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Definition
INC risk for invasive breast cancer, stroke, venous thromboembolism, and coronary artery disease. |
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Term
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Definition
CI - Pt w/ pre-existing hypercalcemia |
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Term
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Definition
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Term
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Definition
MOA - Blocks RANKL to prevent formation of osteoclasts |
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Term
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Definition
Caution: HTN crisis caused in pt taking MAO-i INC intraocular pressure in Glaucoma Pt Possible arrhytmia in cardiac Pt |
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Term
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Definition
Interferes w/ metabolism of 6-mercaptopurine (anti-cancer) and azathiopurine (immunosuppressant) |
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Term
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Definition
MOA - Blocks adenosine receptors |
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Term
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Definition
Fall Risk due to postural hypotension, sedation, arrythmia |
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Term
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Definition
Mineralocorticoid that causes volume expansion. Used to tx orthostatic hypotension |
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Term
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Definition
Raise systemic vascular resistance |
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Term
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Definition
Include in Tx of Postprandial Hypotension |
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Term
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Definition
Can prolong normal or complicated grief |
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Term
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Definition
First line depression medication in elderly |
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Term
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Definition
Less likely to cause hypoglycemia than SU/Insulin |
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Term
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Definition
In patient with creatine clearance over 1.5 and GFR over 60, lactic acidosis risk will be LOW. |
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Term
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Definition
Avoid in elderly pt due to risk of rebound HTN |
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Term
Steroids, Sym Agonists, Decongestants, NSAID's, Cyclosporine, Tacrolimus, Erythropoietin |
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Definition
Medications known to INC BP |
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Term
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Definition
Analgesic effect in pt w/ vertebral fractures |
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Term
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Definition
Assoc w/ lower extremity edema |
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Term
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Definition
ADR - urinary retention, constipation, delerium, dry mouth, blurred vision, increased HR |
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Term
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Definition
Poorly tolerated due to local skin effects |
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Term
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Definition
Anticholinergic used to tx detrusor overactivity |
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Term
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Definition
Tx of detrusor underactivity |
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Term
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Definition
Alpha agonist that tightens sphincter in stress incontinence. |
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Term
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Definition
Causes bladder sphincter relaxation |
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