Term
pressures on the right side are lower than the left side-explain the pathology |
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Definition
if you have left to right shunting, hihg pressure goes to right atrium side and then is sent back to the lungs. This will lead to over oxygenated blood
you can develop pulomary hypertensio- long term consequense right side exceed to left side |
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Definition
air flows from right to left never having touched air this leads to depxygenated blood and cyanosis keisenmengers pulmonary vascular disease |
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Definition
can still live for 20-30 years along the way trashing their pulmonary circulation...fatal disease |
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Definition
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pulmonary artieries branch with |
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Definition
airways and then go till the terminal bronchioles thebn branch and create s heet of blood interrupted by alveolar wall |
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distance from alevolars to artery |
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Definition
.3 microns surfactant alvelor i intersit endo plasma redcell |
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pulmonary blood vessels are |
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Definition
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Definition
muscular and have abundant smooth muscle to regulate blood flow to various organs |
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Definition
exagerrated proliferation meth or cocaine, virus exagerrated inflammatory response |
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pulomanry circulation must accept |
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Definition
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Term
Pulmonary vascular resistance |
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Definition
pressure difference in lung/cardiac output |
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Definition
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passive factors that affect pulomary vascular resistance |
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Definition
cardiac output/hydrostatic change lung volumes/inhalation lung position/gravity/orthostatic change positive pressure ventilation |
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active things that cause pulmonary resistance |
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Definition
acidemia hypoxia sympathetic tone hypercapnia-too much CO2 |
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Pulmonary vascular resistance in some cases can become _____ as pressures rise |
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Definition
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How does pulmonary vascular resistance become lower in the face of increased pressure |
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Definition
recruitment and distension |
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Term
pulmonary capillaries ar esurrounded by |
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Definition
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alveolar gas can collapse the |
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Definition
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pulmonary arteies and veins pressure around them may be less than the alveolar pressure due to |
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Definition
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Definition
extra alveolar vessels expand |
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vascular resistance from low to high |
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Definition
very low to middle it decreases then it increases |
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at low lung volumes, extraalveolar vessels |
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Definition
small caliber due to their intrinsic smooth muscle/elastic tisse |
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critical opening pressure |
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Definition
the pressure necessary to initiate blood flow through pulmonary vessels within a collapsed lung |
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at large lung volumes vascular resistance |
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Definition
increases due to stretched alveolar walls |
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where is resitance lowest |
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Definition
functional residual capacity |
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more ventilation and blood flow |
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Definition
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Definition
P alveolar>parterial>pvenous no flow pathological condition shock ventilated but not perfused |
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Definition
parterial.palveolar.pvenous blood flow dictated by the difference between parterial and palvolar waterfall starlings |
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Definition
parterial.pvenous.palveoli |
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Definition
atalactatic lung blood vessels and alveoli collapse |
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____ factors dominate PVR and blood flow distribution normally |
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Definition
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Definition
hypoxic pulmonary vasconstircitoon.
no cns occurs in excised segement of pulmonary artery the PO2 of alveolar gas no thte arterioklar blood |
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Definition
non linear when pO2 is below 70 mm Hg lots of vasoconstiction |
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HPV Causes blood to flow to or way from hypociv regions |
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Definition
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nitric oxide is a vaso_____- |
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Definition
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Definition
suldenofil improvign downsttream cyclic g protein vasodialtor may promote endothelial formation |
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Definition
hpv very high then breath relaxation of smooth muscle tone |
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Definition
starling's law fluid out hydrostatic fluid in colloid |
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Definition
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interstitium around the extralveolar vessels perivascular and peribronchial lymphatics drain into hilar nodes |
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hydrostatic pressure out colloid pressure___ |
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Definition
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Definition
mismatch contributes to hypoxemia and dead space ventilation |
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