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what is lef tint eh lung and has to be pushed out |
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funcitonal residual volume |
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Definition
what is left after a normal breath |
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Term
what is measured by a spriometer |
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Definition
tidal volume vital capacity |
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helium diluation is used to find |
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Definition
functional residual capacity |
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Definition
a closed box. the patient inspires and takes volume from the box increasing pressire in teh box |
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tidal volume and vital capacity can be mesured using |
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Definition
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total lung capacity residual volume and functional residual volune need to be measured |
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Definition
using a plethysmograph or helium dilution |
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why is helium dilution use helium? |
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Definition
becaue it is very low solubility |
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use of the plethysmograph depends on |
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Definition
ventuilation by breath times numebr of breaths |
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of each 500 ml breath how much reaches alveolar |
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Definition
150 ml does not reach alveolar |
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the amount of fresh inspired air available for gas exchange |
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tidal volume is a mixture of |
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Definition
volume from the dead space and alveolar volume |
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Definition
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we can measure alveolar volume by measuring |
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Definition
volume of co2=alveolar volume times percentage of co2 |
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anatomic dead space ______ with large breaths |
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Definition
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Definition
way of measuring anatmoic dead space |
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Definition
area of conducting poriton fo the respiratory system |
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area that doesn't do co2 elimination |
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two dead spaces are almost |
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Definition
identical, but phsyiological dead space is increased ind isease states |
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lower regions of the lung ventilate____ than upper |
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how do we determine which portions ventilate better? |
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Definition
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anatomic dead space can be measured |
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Definition
fromt he nitrogen concentraion following a single inspiration of oxygen |
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phgysiological dead space measured using |
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Definition
bohr method and the expried co2 |
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Term
02 is carried in the blood in two forms |
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Definition
dissolved and attached to hemoglobin |
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Definition
Henry's law, that is the amount dissovled is proportional to the partial pressure |
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.003 percent by volume 02 in |
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Definition
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iron prporphyrin compound, this is jointed to the protein globin which consistes of 4 polypeptides |
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types of chains in globin |
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adult hemoglobin is known as |
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has valine instead of glutamic acid in the beta chains |
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hemoglobin can have the ferrous_____ |
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Definition
oxidized to the ferric fform by nitrites, sulfonamides and acetanilid |
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the ferric form of hemoglobin is known as |
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the meaximum amount of O2 that can be comined with Hb is called the |
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Definition
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90 percent of arterial co2 is in the form of |
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Definition
bicarbonate 5 percent as carbamine 5 percent dissovled |
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Definition
60 percent bicarbonate 30 percent carbamino 10 percent dissolved |
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like o2, co2 obeys henry's law |
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Definition
but co2 is much more soluable than 02 dissolved co2 is a significant poriton fo the the co2 |
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Definition
enzyme located in red blood cells converting carbon dioxide and wter into h2 co3 |
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CO2 curve is _____ to the o2 curve |
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acidemia and alkalemia can or cannot coexist |
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acidosis and alkalosis can or cannot coexist? |
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decreases myocardial contactility, arterial tone, pulmonary cascular resistance predispose to arrythmias right shift oxygen binding curve |
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Definition
predisposes to arrythmias, shifts ohgb curve to the left causes cerebrocvascular constriction and reduced cerebral blood flow |
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acid base disturbances can be ____ or _____ |
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Definition
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With ____ disporders, the pH is isially brought to near normal compensatory mechansism |
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Definition
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examples of simple disorders include |
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Definition
metabolic acidossi, pH and HCO3 low metabolic alkalosis ph high and hco3 high respiratory acidosis ph is low and paco2 is high respiratory alkalossi ph is high and paco2 high |
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mixed disorders can include combinations of metabolic disorders or _____- |
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Definition
combination of metabolic and respiraotry diseases. |
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metabolic acidosis can be associated with ___ or _____ ion gap |
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difference between na- (cl +hco3) normal is 10-14 |
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metabolic acidosis associated with elevated anon gap can be caused by a vareity disorders |
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Definition
Salicylate Lactic acidosis Uremia Methanol ingestion Paraldehyde ingestion Ethylene glycol ingestions Diabetic ketoacidsos |
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metabolic acidosis associated iwth a normal anion gap |
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Definition
loss of HCO3 gi proximal colostomy kidneys proximal renal tubular acidosis renal tubular disease |
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