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Herbal Pharmacology
Herbal Pharmacology and Drug Interactions
97
Medical
Graduate
03/05/2012

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Cards

Term
Extract in pungent herbs
Definition
Volatile Oils
Term
Extract in sweet herbs
Definition
Amino acid, sugar, glycoside
Term
Extract in bitter herbs
Definition
Alkaloid, glycoside
Term
Extract in sour herbs
Definition
Tannic acid, organic acids
Term
Extract in salty herbs
Definition
Iodine, inorganic salts
Term
Function of pungent herbs
Definition
Regulate qi and stop pain; expel exterior
Term
Function of sweet herbs
Definition
Tonify qi; improve immune function
Term
Function of bitter herbs
Definition
Antibacterial, antiviral, anti-inflammatory
Term
Function of sour herbs
Definition
Astringent; generates fluid, soothes Liver
Term
Special instructions for cooking pungent herbs
Definition
Do not cook too long because oils evaoprate
Term
What is the main constituent of Huang Lian?
Definition
Berberine
Term
What are the main components of Ma Huang?
Definition
L-ephedrine
D-pseudoephedrine
Term
What are the main effects of Ma Huang?
Definition
Induce Sweating
Relieve Asthma
Induce Diuresis
Anti-inflammatory, anti-allergic
Stop cough, expectorant
Reduce fever (antibacterial and antiviral)
Excite CNS
Stimulate Heart and increase blood pressure
Term
What are the indications of Ma Huang?
Definition
Bronchial asthma
Stuffy nose
Low blood pressure
Cold-type urticaria
Term
What are the side effects of Ma Huang?
Definition
Bleeding eyes
CV and nervous system effects
Restlessness, insomnia
Term
What are the drug interaction cautions for Ma Huang?
Definition
Avoid with medications meant to lower blood pressure
Avoid with medication that promotes sweat (including aspirin)
Caution with viagra - words on a2 receptors
Term
What are the adverse effects of Ma Huang?
Definition
Nervousness, anxiety, palpitations, headache, nausea, hypertension, seizures, strokes, MI, hyperthermia, death, myocardial ischemia, dysrhythmias, controlled hypertension, increased oxygen demand of heart in atherosclerosis cases, cerebral vascular ischemia, intracranial hemorrhage, CNS vasculitis, neural toxicity, acute psychosis
Term
What are the main components of Gui Zhi?
Definition
Cinnamic aldehyde
Cinnamic acid
Phenylpropyl acetate
Volatile ois
Term
What are the effects of Gui Zhi?
Definition
Dilate blood vessels - promote sweating and blood circulation
Reduce fever and stop pain, especially cold pain in the extremities
Tranquilize, anticonvulsion
Anti-inflammatory, antiallergic
Antibacterial, antiviral
Term
What is an indication of Gui Zhi?
Definition
Cardiac pain (Opens Heart Yang
Term
What is a side effect of Gui Zhi?
Definition
May cause thirst in high doses
Term
What are the main components of Chai Hu?
Definition
Saiko-sidea-d
a-spinastral
Volatile oils
Fatty acid
Term
What are the effects of Chai Hu?
Definition
Abate fever
Tranquilize, analgesic, stop cough
Promote immunity- strengthen Kupffer and NK cells
Protect LV, benefit GB
Treat ulcers
Relax intestinal spasms
Term
What are the indications of Chai Hu?
Definition
Alternating chill/fever, hypochondriac pain, irregular menstruation, prolapsed uterus, respiratory infection, cough due to lung disease, viral hepatitis, high cholesterol, LV/GB issues (stone, worm, pain, etc.)
Term
What are side effects of Chai Hu?
Definition
Sleepiness, poor appetite, abdominal distention

Injection may lead to allergic reaction
Term
What are drug interaction cautions for Chai Hu?
Definition
Increase risk of bleeding with "bleeding drugs"
Stimulate adrenals and decrease the effects of antihypertensives
caution with cholesterol-lowering agents
may increase drug-induced drowsiness
Term
What are the main components of Ge Gen?
Definition
Diadzin
Diadzein
Puerarin
Term
What are the effects of Ge Gen?
Definition
Reduce fever
Effects on circulatory system
Relax smooth muscles of the intestines
Reduce function of platelets
Lower blood sugar
Term
What are indications of Ge Gen?
Definition
Hypertension
Coronary Heart Diseases
Migraines
Term
What are side effects of Ge Gen?
Definition
Intravenous puerarin can lead to a and b hemolysis
Intraperitoneal puerarin causes hypothermia
May cause weight loss
Term
What are drug interaction cautions for Ge Gen?
Definition
Antidiabetics
Anticoagulant and antiplatelet drug
Term
What is an additional caution for Ge Gen?
Definition
Not recommended in pregnant or breastfeeding women
Term
What are the main functions of herbs that relieve the exterior?
Definition
Induce sweat, abate fever, analgesic, regulate immune function and inflammation, anti-anaphylaxis (IGE), antibacterial, antiviral, anti-tissue and expectorant
Term
What are the main functions of herbs that clear heat syndromes?
Definition
Anti-microbial, anti-toxin, anti-pyretic, effects on immune system, anti-inflammatory, anti-cancer, expel free radicals
Term
What are the main components of Huang Lian?
Definition
Berberine, coptisine, Worenine, Palmatine
Term
What are the main effects of Huang Lian?
Definition
Anit-microbes, anti-toxin, anti-pyretic, affect immune system and CV system
Term
What are the indications of Huang Lian?
Definition
Hypertension, supra-ventricular arrhythmia, DYSENTERY, acute enteritis, cholecystitis, Respiratory tract infections, diabetes
Term
What are the side effects of Huang Lian?
Definition
Drug rash from IV Huang Lian
GI effects from oral dose of single herb - fullness, nausea, vomit
Term
What are the side effects of berberine?
Definition
high doses may lower blood pressure; dyspnea, flu-like symptoms, GI discomfort, cardiac damage
Term
What are the indications of Berberine?
Definition
Bacterial diarrhea, intestinal parasites, ocular infections
Term
What are the main components of Huang Qin?
Definition
Flavinoids: Baicalin (12-17 %), Baicalein, Wogonin
Term
What are the main effects of Baicalin?
Definition
Inhibit infection, anti-inflammatory, inhibit cancer proliferation, protect bone marrow, promote hemopoiesis, protect intestines from chemo, lower BP, sedative, bile secretion, neuroprotective, hepatoprotective
Term
What are the main effects of Huang Qin?
Definition
Antioxidant, antiviral, antibacterial, anti-allergic, antihistamine, anti-acetylcholine, anti-anaphylaxis, anti-tumor
Term
What are the indications for Huang Qin?
Definition
Cardiovascular disease, cancer, cataracts, aging, inflammatory disease, neurological disease
breast cancer and prostate cancer
atherosclerosis
Term
What are the ingredients of Shuang Huang Lian (SHL)?
Definition
Jin Yin Hua
Huang Qin
Lian Qiao
Term
What are the indications of Shuang Huang Lian?
Definition
Respiratory tract infections; viral myocarditis
Term
What are the main effects of Qing Hao?
Definition
Antimalarial, antibiotic, antihypertensive, antipyretic, cholagogic
Term
What are the main indications of Qing Hao?
Definition
Malaria
Jaundice
Term
What are the main components of Zhi Mu?
Definition
Timosaponin
Mangiferin
Sarssapogenin
Term
What are the main effects of Zhi Mu?
Definition
Antimicrobial, antidiabetic, antipyretic
Term
What is the main caution for treating patients with Zhi Mu?
Definition
Administer gradually and briefly for patients taking diabetes medications
Term
What are the ingredients of Coptis Detoxicating Decoction (Huang Lian Jie Du Tang)?
Definition
Huang Lian
Huang Qin
Huang Bai
Zhi Zi
Term
What are the main effects of Huang Lian Jie Du Tang?
Definition
Purge fire and expel toxin for fire toxin obstructing the three jiao
Antimicrobial, antitoxin, antipyretic, effects on immune system, lower blood pressure, promote cerebral circulation, antipeptic ulcer
Term
What are the main indications for Huang Lian Jie Du Tang?
Definition
Excess heat conditions in all three jiao
Senile dementia, dementia due to cerebral ischemia
septicemia, pyotoxinemia, tonsilitis, hypertension, diseases of cerebral vessels, sequelae of wind stroke, alzheimers, herpes zoster
Term
What are the side effects of Huang Lian Jie Du Tang?
Definition
nausea, vomiting, constipation
Long-term use damages the spleen and causes diarrhea
Term
What are the main actions of herbs that purge?
Definition
purge intestines, induce urination, antimicrobial, anti-toxin, anti-amoebic dysentery, anti-inflammatory, anti-cancer
Term
What are examples of herbs that purge and depress cancer?
Definition
gan sui, yuan hua, da ji, qian lin zi, bing ma zi
Term
What are the main components of Da Huang?
Definition
Anthraquinone
Glycoside
Rhein
Chrysophanol
Emodin
Acatechin
Gallic acid
Term
What are the main effects of Da Huang?
Definition
Purge heat to clear constipation and clear GI tract
Invigorate blood to remove stasis, also stops bleeding
Protect LV and benefit GB
Promote renal function
anti-infection
Anti-cancer
Term
What are the indications of Da Huang?
Definition
Constipation, ulcer hematemesis, dysentery and acute enteritis, acute abdominal inflammation (pancreatitis, peritonitis)
Renal failure
Hyperlipidemia
Term
What are the side effects of Da Huang?
Definition
Long term use causes pathologic changes in LV and thyroid
Term
What are the drug interaction cautions for Da Huang?
Definition
Prolonged use may cause loss of potassium leading to increased toxicity of cardiac glycosides, such as digoxin. You can prevent this by increasing your potassium intake
Term
What are the adverse effects associated with Da Huang?
Definition
Nausea, vomiting, diarrhea, abdominal pain
Term
What are the ingredients for Da Cheng Qi Tang (Major Order the Qi Decoction)?
Definition
Da Huang
Mang Xiao
Hou Po
Zhi Shi
Term
What are the main effects of Da Cheng Qi Tang?
Definition
Purge by stimulating intestinal movement
Effects on intestinal obstruction
Antibacterial
Term
What are the main indications of Da Cheng Qi Tang?
Definition
Yang Ming fu organ disorder with dry stool in the intestines
Pancreatitis, Appendicitis
Term
How do you administer Da Cheng Qi Tang in severe acute stages?
Definition
External or anal administration
Term
What are the mechanisms involved in Ma Huang's ability to induce sweating?
Definition
reduces sweat glands' ability to reabsorb sodium

Stimulate CNS and alpha receptors
Term
What are the mechanisms involved in Ma Huang's ability to relieve asthma?
Definition
Stimulate adrenergic nerves to release adrenaline
Raise intracellular cAMP to relax bronchial muscles
Prevent inflammation
Term
What are the mechanisms involved in Ma Huang's ability to induce diuresis?
Definition
works on renal tubules
Dilates potassium channel to improve blood circulation
Prevent from reabsorbing sodium
Term
What are the mechanisms involved in Gui Zhi's ability to dilate blood vessels, promote sweat and blood circulation?
Definition
Cinnamic aldehyde increases blood flow to the skin, especially when taken with Ma Huang
Term
What mechanisms are involved in Gui Zhi's ability to reduce fever and stop pain?
Definition
Related to promoting sweat
Increases pain threshold
Stops itch
Term
Which microbial infections can Gui Zhi treat?
Definition
Staph
TB
Influenza
ECHO11
Term
What components of Chai Hu abates fever, and what causes of fever do they treat?
Definition
Saiko-side and volatile oils abate fever due to typhoid bacillus and colibacillus
Term
Which component of chai hu works as a tranquilizer, analgesic, and cough suppressant?
Definition
Saiko-side
Term
Which component of chai hu protects the liver and benefits the gallbladder in cases like HBV?
Definition
Saiko-side
Term
What do you use to prepare chai hu in order to lower cholesterol?
Definition
Vinegar
Term
Which component of Chai Hu treats ulcers, and how does it work?
Definition
Saiko-side
Protects the stomach lining
Term
What types of drugs are used with caution when prescribing Chai Hu?
Definition
aspirin, blood thinners, NSAIDs, beta blockers, ACE inhibitors, cholesterol-lowering agents, drugs that cause drowsiness
Term
What effects do Ge Gen have on the circulatory system?
Definition
Puerarin can reduce blood pressure
promotes circulation of the brain
dilates coronary vessles, relaxes spasms of coronary vessels, improves heart function
Term
What effects do Huang Lian have on the cardiovascular system?
Definition
Reduce ventricular arrhythmia, ventricular fibrillation, atrial flutter
Promote cardiac contractility
Reduce Heart rate
Lower blood pressure (especially diastolic)
Prevent platelet adhesion
Lower blood sugar, anti cancer
Term
How does berberine treat bacterial diarrhea?
Definition
inhibits secretions by intestinal infections
blocks adherence of bacteria to tissues
Term
What do the antioxidant properties of Huang Qin treat?
Definition
cardiovascular disease, cancer, cataract formation, aging, inflammatory disease, neurological disorders
Term
How do the antitumor properties of Huang Qin work?
Definition
decrease estrogen biosynthesis to treat breast and prostate cancer
Term
How does the antimalarial property of Qing hao work?
Definition
block host erythrocyte
Term
what microbes do qing hao inhibit?
Definition
staph aureus
neisserria catarrhalis
Term
How does qing hao work as a hypertensive?
Definition
decrease heart rate, inhibit contraction of heart muscle
Term
How does qing hao work and an cholagogic?
Definition
increases production and excretion of bile
Term
What microbes do Zhi Mu treat?
Definition
staph aureus
hemolytic strepcholerace
salmonella typhi
e coli
bacillus stutilis
Term
What is an effect of cooking da huang too long?
Definition
increases tannic acid and causes constipation
Term
How does da huang protect the liver and benefit the gallbladder?
Definition
helps the gb contract and promotes bile secretion
lowers serum cholesterol
prolongs the life of liver cells and promotes regeneration
Term
how does da huang treat peptic ulcers?
Definition
controls hydrogen ions and promotes PGE2
Term
What effects does Da Huang have on the blood, and what components cause the effects?
Definition
a-catechin and gallic acid stop bleeding by adhering platelets and contracting blood vessels

also reduces blood stasis
Term
how does da huang promote renal function?
Definition
lowers BUN, cholesterol, triglycerides
growth of renal tubules and mesangial cells
Suppress TNF and IL-1
Term
How does Da Huang treat cancer?
Definition
suppresses RNA and DNA synthesis of cancer cells
Term
How does Da Cheng Qi Tang affect intestinal obstructions?
Definition
promotes circulation
decreases blood deficiency
helps intestines regain functions
Term
Does Da Cheng Qi Tang treat G+ or G- bacteria?
Definition
both
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