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Hepatitis
Therapeutics (V) exam 3
21
Other
Not Applicable
01/29/2013

Additional Other Flashcards

 


 

Cards

Term

HBsAG (-)

Anti-HBc (-)

Anti-HB2 (-)

 

Definition
Susceptable to infection
Term

HBsAG (-)

Anti-HBc (+)

Anti-HB2 (+)

 

Definition
Immune because of natural infection
Term

HBsAG (-)

Anti-HBc (-)

Anti-HB2 (+)

 

Definition
Immune due to the Hepatitis B vaccine 
Term

HBsAG (+)

Anti-HBC (+)

IGM Anti-HBC (+)

Definition
Acute infection
Term

HBsAG (+)

Anti-HBC (+)

IgM Anti-HBC (-)

Anti-HBS (-)

IgG Anti-HBC (+)

Definition
Chronic infection
Term
Hepatitis transmitted Fecal-oral enteral
Definition
  • A
  • E
Term
Hepatitis transmitted Parenterally
Definition
  • B
  • C
Term

HBsAG

  • +
  • -
Definition
  • currently infected
  • susceptable
Term

Anti-HBs

  • +
  • -
Definition
  • Antibodies immune/resolved infection
  • Susceptable
Term

Anti-HBC

  • +
  • -
Definition
  • Self made Antibodies
  • Susceptable
Term

Diagnosis

  • Chronic Hep B (4)
Definition
  1. HBsAg (+) >6M
  2. HBV DNA >20K
  3. Elevated AST/ALT
  4. Biopsy showing necroimflammation
Term
When should treatment for Hep B start? (3)
Definition
  1. HBsAg (+) >6M
  2. HBV DNA >20K
  3. ALT >60 X 3-6M
Term
When can treatment of Hep B end?
Definition
  1. Seroconversion + undetectable viral DNA
  2. At least 6M after anti-HBe
Term

Hep B

  • Drugs
Definition
  • Peg-IF A2
  • Entecavir
  • Tenofovir
Term
Which drug is CI in patients with a CRcl <50?
Definition
Ribavirin is CI in Renal insufficiency
Term
Which drugs are NOT renally dose adjusted?
Definition
  • Boceprevir
  • Telaprevir

Prevent the need to dose adjust

Term
CI as Hep B monotherapy in PT with HIV
Definition
  • Entecavir

Easy E has HIV

Term

Heptitis C 

  • Treatment
Definition
  • PEG-IF
  • Ribovirin
Term
How do we confirm the diagnosis of hep C infection
Definition
RNA serology
Term

Hep D

  • Prevention
  • Treatment
Definition
  • Hep B vaccine
  • IF
Term
Which drug is teratogenic?
Definition

Ribavirin

use two forms of backup

 

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