Term
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Definition
picornavirus ssRNA, encapsulated, non-enveloped transmission: fecal-oral route incubation 3-4 weeks Detection: IgM Ab (titer 4x inc) Vaccine available |
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Term
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Definition
hepaDNAvirus partially ds DNA, encapsulated and enveloped transmission: parental, sexual, maternal-fetal incubation 2-3 mos detection via serologic assay for presence of: HBsAg, HBsAb HBcAg, HBcAb HBeAg, HBeAb determines status of disease |
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Term
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Definition
ssRNA circular, enveloped c HBsAg Transmission: parenteral, sexual, maternal-fetal no virion pol, requires HBV for virulence Detection of IgM to delta-Ag, delta-Ag itself, or HDV-RNA in serum or liver |
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Term
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Definition
flavivirus ss+RNA, enveloped multiple serotypes no vaccine transmission: parenteral, sexual, maternal-fetal incubation 7-8 wks increase HCC risk detection of anti-HCV in ELISA -> confirm c immunoblot and PCR detection of viral RNA in serum -> active dx |
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Term
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Definition
flavivirus chronic disease detection of viral RNA by PCR |
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Term
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Definition
ss+RNA enveloped cause of waterborne epidemics worldwide no chronic or carrier state dx by exclusion |
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Term
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Definition
vector: mosquito 2 cycles: - jungle cycle: dx of monkeys - human is an accidental host
- urban cycle: dx of humans
clinical manifestations: jaundice and fever; pathologic changes in heart, liver, kidneys, upper GI tract prevention: live attenuated vaccine |
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