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Hepatitis Lab Tests
Overview
29
Audiology
4th Grade
10/19/2013

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Cards

Term
fever, jaundice, dark urine, fatigue, malaise, anorexia, nausea, abdominal discomfort
Definition
Acute hepatitis
Term
fatigue, jaundice
Definition
chronic hepatitis
Term
leak into blood stream when cells are damaged, can vary over time; Males can have higher levels than women
Definition
Liver Enzymes
Term
0-50 IU/L; found in liver; Men 30 IU/L; women < 19IU/L
Definition
ALT
Term
0-45 IUL; found in liver and red cells, cardiac and skeletal muscles; African-American males can have higher levels than Caucasian males
Definition
AST
Term
Livery Biopsy
Definition
risky if: high INR, low platelets
Term
first to appear in hepatitis A (detectable 5-10 days before symptom onset
Definition
IgM (anti-HAV)
Term
appear early in hepatitis A, remains positive for life (life-long protection)
Definition
IgG
Term
referred to as anti-HAV; + indicates protection
Definition
Total anti-HAV (IgM-IgG)
Term
surface antigen in Hepatitis B
Definition
HVsAg
Term
immunity (infection or vaccine) in Hepatitis b
Definition
Anti-HBs
Term
sensitive marker of infectious in hep B
Definition
Anti-HBc
Term
envelop (highly infectios) in hep b
Definition
HBeAg
Term
low infectivity in hep b
Definition
Anti-HBe
Term
"viral load"
Definition
HBV DNA
Term
main screeningsay in hepatitis C serologic tests
Definition
Antibodies (anti-HCV)
Term
time to seroconversion (Anti-HCV)
Definition
4-10 weeks
Term
confirm Ab presence (HCV)
Definition
RIBA (immmuno-blot)
Term
confirmation for a positive test; manual or semi-automated RT-PCR or TMA
Definition
qualitative viral load (HCV-RNA)
Term
treatment course; manual or semi-automated RT-PCR, bDNA, real-time PCR
Definition
Quantitative Viral Load (HCV-RNA)
Term
POSITIVE Anti-HCV and POSITIVE HCV RNA
Definition
acute or chronic depending on clinical context
Term
POSITIVE Anti-HCV and NEGATIVE HCV RNA
Definition
resolution of HCV or acute HCV during period of low-level viremia
Term
NEGATIVE anti-HCV and POSIIVE HCV RNA
Definition
early acute HCV or chronic HCV in setting of immunosuppression or false + HCV RNA test
Term
NEGATIVE anti-HCV and NEGATIVE HCV RNA
Definition
absence of infection
Term
baseline evaluation in hep c- indicated only for patients with cirrhosis; consider if HIV +
Definition
AFP (alpha fetoprotein)
Term
baseline evaluation in hep c- indicated only for patients with cirrhosis; consider if HIV +
Definition
AFP (alpha fetoprotein)
Term
follow up for Hepatitis A
Definition
maybe liver enzymes a few months later
Term
follow up for Hepatitis B
Definition
ALT and other LFTs; HBV RNA; biopsy; serological markers; renal function for med adjustments
Term
follow up for Hepatitis C
Definition
ALT and other LFTs; HCV RNA; biopsy; AFP; tests for extra hepatic manifestations; med side effects( i.e. anemia)
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