Term
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Definition
-Storage and filtration of blood
-metabolism and storage of xenobiotics, nutrients and other compounds
-secretory and excretory activities in bile formation
-synthesis of blood plasma constituents |
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Term
| liver is susceptible to chemical damage because of.... |
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Definition
-anatomical position
-metabolic functions
-enterohepatic circulation
-high concentration of binding sites |
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Term
| factors in liver toxicity |
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Definition
-location and specialized process for uptake and biliary secretion
-Abundant capacity for bioactivation influences rate of exposure |
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Definition
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Definition
| secrete cytokines and nitric oxide |
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Term
| stellete cells ( ito cells) |
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Definition
| vitamin a storage secrete collogen |
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Term
| acute toxic effects of liver |
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Definition
-steatosis
-necrosis
-hepatitis
-choleostasis |
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Term
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Definition
-increased synthesis of tryglycerides
-decreased protein synthesis
-inhibition formation or assembly
-inhibition or release of VLDL |
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Term
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Definition
-loss of drug metabolizing enzymes
-loss of glucose-6-phosphates
-loss of protein synthesis
-loss of capacity to form and excrete VLDL |
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Term
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Definition
-active fibroplasia associated with inflammation
-ito cellsy synthesize and secrete collagen
-ethanl, carbon tet, pvc |
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Term
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Definition
-disorganization of liver architecture by widespred fibrosis and nodule formation
-alcoholism, viral hepatitis |
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Definition
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Definition
-fatty liver
-chirrhosis
-steatosis
-fibrosis |
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Definition
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Definition
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Term
| anabolic and contraceptive steroids |
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Definition
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Definition
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Definition
| inhibit secretion of VLDL(steatosis) |
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