Shared Flashcard Set

Details

Heme-Genetics
Genetics
8
Medical
Graduate
01/03/2011

Additional Medical Flashcards

 


 

Cards

Term
Translocations associated with Burkitt Lymphoma (3)
Definition

t(8;14)(q24;q32)

t(8;22)(q24;q11)

t(2;8)(q11;q24)

 

Myc gene translocations.

Term

Translocation associated with CML.

 

What is the oncogene?

Definition

t(9;22)(q34;q11)

 

BCR-ABL fusion protein (Chimeric)

Term

 

Translocation associated with Acute Lymphoblastic Leukemia.

 

What is the oncogene?

 

Definition

t(1;19)(q23;p13)

 

TCF3-PBX1 

Term

 

Translocations associated with Acute Lymphocytic Leukemia?

 

What is the oncogene?

 

Definition

t(9;22)(q34;q11)

 

BCR-ABL fusion protein (Chimeric)

Term

Translocation associated with Acute Promyelocytic Leukemia.

 

What is the oncogene?

Definition

t(15;17)(q22;q11)

 

RARA-PML

Term

Translocations associated with Chronic Lymphocytic Leukemia.

 

What is the oncogene?

Definition

t(11;14)(q13;q32)

 

BCL 1

Term

Translocation associated with Follicular Lymphoma.

 

What is the oncogene?

 

Definition

t(14;18)(q32;q21)

 

BCL 2

Term
What are the translocations associated with Burkitt Lymphoma(3)?
Definition

The c-Myc gene on 8 is translocated to:

t(8;14) at the IgH locus

t(2;8) at the Igκ locus

t(8;22) at the Igλ locus

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