Term
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Definition
| THE PHAGOCYTE - MOST ABUNDANT - ANTIMICROBIAL |
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Term
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Definition
| PARASITE DESTROYER - ALLERGY INDUCER |
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Term
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Definition
| ALLERGY HELPER - IGE RECEPTOR - HISTAMINE RELEASE |
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Term
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Definition
| THE DESTROYER - MP (HYDROLYTIC ENZYMES, COFFEE BEEN NUCLEUS (CD 4 -> TISSUE -> CD14 GRADUATE IN LEVEL) |
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Term
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Definition
| THE WARRIOR - T B NK CELLS |
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Term
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Definition
| THE CLOTTER - NO NUCLEI, SMALLEST CELL |
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Term
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Definition
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Term
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Definition
| BABY NEUTROPHILS - COMES OUT WITH THE GANG AS BACK UP IN FIGHT |
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Term
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Definition
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Term
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Definition
| LEUKEMOID REACTION, SEEN IN BURN PT - EXTREME DEMARGINATION (LOOKS LIKE LEUKEMIA ALMOST) |
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Term
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Definition
| LEUKEMIA (WHEN <5% ITS ACTUALLY A LEUKEMOID REACTION) |
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Term
| HIGH WBC N' BANDS TELL YOU? |
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Definition
| LEFT SHIFT - HAVE AN INFECTION |
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Term
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Definition
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Term
| DISEASES WITH HIGH EOSINOPHILS |
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Definition
| NAACP - NEOPLASMS, ALLERGY/ASTHMA/ADDISONS DISEASE (RELATIVE ESOINOPHIL DUE TO LACK OF CORTISOL CALLING THEM), COLLAGEN VASCULAR DISEASE (CAN'T MARGINATE), AND PARASITES |
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Term
| DISEASE WITH HIGH MONOCYTES >15% |
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Definition
| STELS - SYPHILIS (CHANCRE, RASH, WARTS), TB (HEMOPTYSIS, NIGHT SWEATS), EBV (TEENAGER SICK FOR MONTH), LISTERIA (BABY SICK, BAD MILK), SALMONELLA (FOOD POISONING) |
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Term
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Definition
| RBCC BEING DESTROYED PERIPHERALLY (BM NO AFFECTED) |
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Term
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Definition
| BM AFFECTED, NOT WORKING RIGHT, DOWN PRODUCTION |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| DIFF BETWEEN PLASMA N' SERUM? |
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Definition
PLASMA - NO RBC, HAS CLOTTING FACTORS
SERUM - NO RBC OR FIBRINOGEN |
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Term
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Definition
| CHRONIC GRAN DZ, LOW COMPLEMENT DISEASE, NADPHA OXIDASE DEF - RECURRENT STAPH/ASPERGILLUS INFECTIONS - NITROBLUE TTZ STAIN IS NEGATIVE |
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Term
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Definition
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Term
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Definition
| LAZY LYSOSOME SYNDOMRE - LYSOSOMES ARE SLOW TO FUSE AROUND BACTERIA |
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Term
| ORGAN CAN MAKE RBC IF BONES FAIL? |
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Definition
| SPLEEN - CAUSES SPLENOMEGALY |
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Term
| WHAT CAUSES A SHIFT TO THE RIGHT IN HB CURVE? |
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Definition
| INCREASE CO2, ACID/ALTITUDE, 2,3 DPG, EXERCISE, TEMP |
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Term
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Definition
| COMPETIITIVE INHIB OF O2, ON HB - CHERRY RED LIPS, PINKISH SKIN HUE |
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Term
| HOW DOES CYANIDE POISON HB? |
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Definition
| NON-COMP INHIBIT OF 02, ON HB - ALMOND BREATH |
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Term
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Definition
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Term
| ACUTE INTERMITTENT PORPHYRIA |
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Definition
| INCREASED PORPHYRIN, URINE DELTA-ALA, PORPHOBILINOGEN --> ABDO PAIN, NEUROPATHY, RED URINE |
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Term
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Definition
| SUNLIGHT - SKIN BLISTES W/PORPHYRIN DEPOSITS, WOOD'S LAMP -- ORANGE-PINK |
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Term
| ERYTHROCYTIC PROTOPORHYRIA |
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Definition
| PORPHYRIA CUTANEA TARDA IN A BABY |
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Term
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Definition
| HOMOZYGOUS, HbS - GLU 6 - VAL -- VASO-OCCCLUSION, NECROSIS, DACTYLITIS, PAINFUL FINGERS/TOES AT 6PM, PROTECTS AGAINST MALARIA |
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Term
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Definition
| HETEROZYGOUS HBs - PAINLESS HEMATURIA, SICKLE WITH EXTREME HYPOXIA (CAN'T BE PILOT OR FIREMAN) |
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Term
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Definition
| GLU6 - LYS - STILL CHARGED, SO NO SICKLING (ITS OUTSIDE THE CELL) |
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Term
| WHAT IS ALPHA THALASSEMIA? |
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Definition
1 DELETION NORMAL
2 DELETIONS 'TRAIT' MICROCYTIC ANEMIA
3 DELETIONS HEMOLYTIC ANEMIA - HB H= B4 |
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Term
| WHAT IS BETA THALASSEMIA? |
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Definition
1 DELETION MINOR - INCREASED HBA2 AND HB4
2 DELETION TRAIT/INTERMIDIA/MAJOR: ONLY IF HBA2 AND HBF --> HYPOXIA AT 6MO |
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Term
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Definition
| SEE W/BETA-THALASSEMIA MAJOR, NO HbA - EXCESS RBC PRODUCTOIN -- BABY MAKING BLOOD FROM EVERYWHERE - FRONTAL BOSSING WITH HEPATOSPLENOMEGALY n' LONG EXTREMITIES |
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Term
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Definition
THROMBOSIS RISK FACTOR -
1/TURBULANT BLOOD FLOW, SLOW
2/HYPERCOAGULABLE, STICKY
3/VESSEL WALL DAMAGE, ESCAPES |
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Term
| WHAT DOES ACUTE HYPOXIA CAUSE? |
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Definition
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Term
| WHAT DOES CHRONIC HYPOXIA CAUSE? |
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Definition
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Term
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Definition
| RBC DESTROYED BY BLOOD VESSELS - LOW HAPTOGLOBIN (BINDS FREE FLOATING HB, ITS LOW B/C ITS ALL BOUND Up!) |
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Term
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Definition
| RBC DESTROYED BY SPLEEN - PROBLEM WITH RBC MEMBRANE, SPLENOMEGALY |
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Term
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Definition
| DELTA ALA DEHYDRASE, FERROCHELATASE |
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Term
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Definition
| X ^ 2+, ANYTHING FREE FLOATING WITH 2+ CHARGE (CA, MG, ETC) |
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Term
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Definition
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Term
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Definition
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Term
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Definition
| PSEUDO-HYPOPARATHYROIDISM, PSORIATIC ARTHRITIS |
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Term
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Definition
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Term
| DISEASE WITH 2 JOINTED THUMS |
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Definition
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Term
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Definition
| SICKLE CELL DISEASE (MICROINFARCT) |
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Term
| MICROCYTIC HYPOCHROMIC ANEMIAS? |
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Definition
| SMALL AND LACKING HB ANEMIA - FAST Lead - Fe DEF, ANEMIA OF CHRONIC DZ, SIDEROBLASTIC ANEMIA, ALPHA AND BETA THALASSEMIA, PB POISONING |
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Term
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Definition
| MICROCYTIC HYPOCHROMIC, INCREASED TIBC, MENSES, GI BLEED, KOILONYCHIA -- INCREASED TIBC B/C ITS LOOKING FOR FE!!! |
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Term
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Definition
| MICROCYTIC HYPOCHROMIC - DECRASED TIBC, (MHC/MCV - LOW TIBC B/C ITS GOT FE BUT ITS LOSING BLOOD ALL TOGETHER FROM SOMEWHERE |
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Term
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Definition
| MICROCYTIC HYPOCHROMIC - DECRASE IN DELTA-ALA SYNTHASE, BLOOD TRANSFUSIONS (BECAUSE HEME IS AN INHIBITOR OF ALA SYNTHASE IN THE HEME PATHWAY - SO IT GET NEGATIVE FEEDBACK N' SHUTS DOWN) |
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Term
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Definition
| MICROCYTIC HYPOCHROMIC, ALPHA FOR ASIANS - CHR 16 DELETION |
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Term
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Definition
| MICROCYTIC HYPOCHROMIC, B FOR BELOW MEDITERRANEANS - CH 11 POINT MUTATION |
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Term
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Definition
| MICROCYTIC HYPOCHROMIC - DECREASE IN ALA DEHYDROGENASE, DECREASE FERROCHELATASE, XRAY BLUE LINE, EATING OLD PAINT CHIPS |
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Term
| MEGALOBLASTIC ANEMIAS? ONLY 3... |
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Definition
1/VIT B12 DEF (TAPEWORMS, VEGAS, TYPE A GASTRITIS, PERNICIOUS ANEMIA)
2/FOLATE DEF (OLD FOOD, MICROWAVED A LOT, AND GLOSSITIS)
3/ALCOHOL (FETAL ALCOHOL SYNDROME - SMOOTH PHILTHRUM, STUFF DOESN'T GROW) |
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Term
| INTRAVASCULAR HEMOLYTIC ANEMIAS? (ONLY 2...)(DECREASED LEVELS OF HAPTOGLOBIN) |
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Definition
ALL IgM**
1/ G6PD DEF - SULFA DRUGS, MOTH BALLS, FAVA BEANS, SUDDEN DROP IN Hb
2/ COLD AUTOIMMMUNE - MONONUCLEOSIS, MYCOPLASM INFECTIONS, RBC AGGLUTINNATION |
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Term
| EXTRAVASCULAR HEMOLYTIC ANEMIAS (NAME 4...)? |
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Definition
ALL OF EM IgG**
1/SPHEROCYTOSIS (DEFECTIVE SPHERIN OR ANKYRIN, + OSMOTIC FRAGILITY TEST)
2/WARM AUTOIMMUNE (ANTI-RH AB, DAPSONE, PTU, ANTIMALRIALS****, SULFA DRUGS
3/PARAXYSMAL COLD AUTOIMMUNE (BLEEDS AFTER COLD EXPOSURE, DONATH LANDSTEINER AB)
4/SICKLE CELL ANEMIA (CREW HAIRCUT XRAY , AVASCULAR NECROSIS OF FEMUR AND SHORT FINGERS) |
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Term
| PRODUCTION ANEMIA'S - TWO TO THINK ABOUT... |
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Definition
DIAMOND BLACKFAN (NO RBC'S AND 2 JOINTED THUMBS)
APLASTIC ANEMIA (PANCYTOPENIA, AUTOIMMUNE, BENZENE, AZT, CAM, RADIATION |
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Term
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Definition
| LOTS OF IMMATURE CELLS, INCREASED mRNA, PB POISONING |
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Term
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Definition
| UNSTABLE HB INCLUSIONS G6PD DZ |
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Term
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Definition
| PYRUVATE KINASE DEF, LIVER DZ, POST SPLEENECTOMY |
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Term
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Definition
| VIT B12 DEF, PB POISONING |
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Term
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Definition
| PMN LEUKOCYTOSIS (INFECTION, STERIODS, TUMOR) |
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Term
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Definition
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Term
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Definition
| FRAGMENTED RBC, HEMOLYSIS; DIC, HUS, TTP AND VASCULITIS (ALSO HAS BURR CELLS) |
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Term
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Definition
| HP PRECIPITATES AND STICKS TO CELL MEMBRANE - G6PD DEF |
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Term
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Definition
| SPLEEN OR BONE MARROW SHOULD HAVE REMOVED NUCLEI FRAGMENTS (HEMOLYTIC ANEMIA, SLEEN TRAUMA, CANCER |
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Term
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Definition
| FE PPT INSIDE CELL (SIDEROBLASTIC ANEMIA |
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Term
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Definition
| CIGAR CELLS - CELL IN FE IRON DEF |
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Term
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Definition
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Term
|
Definition
| BROKEN RBC, DIC, ARTIFICAL HEART VALVES TEARING UP RBC |
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Term
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Definition
| MACROPHAGES PREG WITH FE (GENETIC OR MULTIPLE TRANSFUSIONS |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
|
Definition
| *****THALASSEMIAS (EASTERN/MEDITTARIAN HIST OF DECENT) OR FE DEF DZ |
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Term
| TEAR DROP CELL - DACROCYTE |
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Definition
| RBC'S ARE BEING SQUEEZED OUT OF BONE MARROW, HEMOLYTIC ANEMIA, BONE MARROW CANCER |
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Term
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Definition
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Term
|
Definition
| BLEEDING IN SKIN N' MUCOSA |
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Term
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Definition
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Term
| INCREASED PTT AND BLEEDING TIME |
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Definition
| VON WILLIEBRAND DISEASE AND LUPUS** |
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Term
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Definition
| BABY WITH BLEEDING FROM SKIN N' MUCOSA - BIG PLATELETS FLOATING AROUND B/C IT NEVER ADHESIONED TO ENDOTHELIUM (LOW Gp1B) |
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Term
|
Definition
| BABY BLEEDING FROM SKIN N' MUCOSA (LOW Gp2/3) -- CAN BE MIMIC'D BY DRUG ABCIXIMAB B/C MOA IS BLOCK THIS! - USED DURING ANGIOPLASTY STENT OR NO STENT |
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Term
|
Definition
| BABY UMBLICIAL STUMP BLEEDING (FIRST TIME ANYONE BLEEDS |
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Term
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Definition
| MUTATION OF FACTOR 5 LEAVES PROTEIN C AND S FLOATING AROUND UNAFFECTED. LEADS TO HEREDITARY HYPERCOAGULABLE STATE. NORMALLY PROTEIN C n' S BREAK DOWN 5 |
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Term
| HOW DOES vWF DISEASE PRESENT? |
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Definition
| HEAVY MENSTRUAL BLEEDING, AUTOSOMAL DISEASE AND PT WILL THINK ITS NORMAL B/C MOM WILL TELL THEM YEAH I BLEED THAT MUCH TOO WHEN I WAS YOUNGER |
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Term
|
Definition
1/TYPE 1 AD, DECREASED PROD OF vWF
2/TYPE 2 AD, vWF AND *****RISTOCETIN AGGREGATION TEST POSITIVE - KEYWORD RISTOCETIN TEST***
3/ TYPE 3, AR - NO VWF - OH FUCK |
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Term
|
Definition
| DEFECTIVE FACTOR 8! - ITS AROUND AND NUMBER IS NOT AFFECTED, THE ACTIVITY IS <40% (REMEMBER ACTIVITY AFFECTED)! -- BLEED INTO CAVITIES, HEAD N' ABDOMEN (CLASSIC DENTIST VISIT, TOOTH WON'T STOP BLEEDING AFTER EXTRACTION) |
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Term
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Definition
| FACTOR 9 MISSING!! (UNLIKE HEM A, WHERE ACTIVITY OF 8 IS DECREASED, HERE IN HEM B THE FACTOR, 9, IS MISSING!!) - BLEED INTO JOINTS*** |
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Term
| DISEASES THAT HAVE LOW LAP SCORE? |
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Definition
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|
Term
| DISEASES THAT HAVE HIGH LAP SCORE? |
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Definition
| LEUKEMOID REACTION - SERIOUS STRESS DEMARGINATION OF WBC |
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Term
| DIFF BETWEEN ACUTE N' CHRONIC LEUKEMIA? |
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Definition
ACUTE - STARTED IN BONE MARROW, SQUEEZES OUT RBC
CHRONIC - STARTED IN PERIPHERY, NOT CONSTRAINED - WILL EXPAND |
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Term
| DIFF BETWEEN MYELOID AND LYMPHOID LEUKEMIAS? |
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Definition
MYELOID - INCREASED RBC, WBC, PLATELETS, MP, (DECREASED LYMPHOID CELLS), BONE MARROW BIOPSY
LYMPHOMA; INCREASED NK, T, B CELLS, (DECREASED MYELOID CELLS) - DO LYMPH NODE BIOSPY |
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Term
|
Definition
| ACUTE, SO BONE MARROW. LYMPHOID, SO DECREASED MYELOID CELLS (NK, T, N' B CELLS ARE UP) -- <15 Y/O PT, BONE PAIN, PAS STAIN POSITIVE, and TdT POSITIVE |
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Term
|
Definition
| ACUTE, SO BONE MARROW. MYELOID, SO INCREASED RBC, WBC, N' MP. -- 15-30YO MALE, SUDAN STAIN, AUER RODS (PEROXIDASE +), M3, VIT A, t15;17 |
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Term
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Definition
| CHRONIC, PERIPHERY STARTING AND MYELOID CELL ARE UP. -- 30-50yo WOMAN t9;22 PHILLY CHR, DECREASED LAP SCORE**** BCL-ABL GENE |
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Term
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Definition
| >60yo MALES, LYMPHADENOPATHY, SOCCER BALL NUCLI, SMUDGE CELLS |
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Term
| WHAT IS HODGKINS LYMPHOMA? |
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Definition
| REED STERNBERG CELLS, EBV, CD30 MARKER FOR CELLS |
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Term
| WHAT IS NON-HODGKINS B CELL LYMPHOMA? |
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Definition
FOLLICULAR 14;18T, BCL-2 (ADULT)
BURKITTS 8;14T, C-MYC, STARRY SKY MP (KIDS) (AFRICAN KID - JAW, AMERICAN - ABDO MASS) |
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Term
| WHAT IS NON-HODGKINS T CELL LYMPHOMA? |
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Definition
MYCOSIS FUNGOIDES; TOTAL BODY RASH
SEZARY SYNDROME; CEREBREFORM CELLS |
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Term
| WHAT IS POLYCYTHEMIA RUBRA VERA? |
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Definition
| HCT >60%, DECREASED EPO****, BUDD CHIARI, PLETHORA "PRURITIS AFTER BATHING" |
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Term
| WHAT IS ESSENTIAL THROMBOCYTHEMIA? |
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Definition
| VERY HIGH PLATELET COUNT (-EMIA), STAINABLE FE, DECREASED C-MPL |
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Term
|
Definition
| MEGAKARYOCYTES, FIBROTIC MARROW - TEAR DROP CELL, EXTRAMEDULLARY HEMATOPOIESIS (SPLEEN MAKING BLOOD) |
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Term
| WHAT ARE PLASMA NEOPLASMS? |
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Definition
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|
Term
| WHAT IS WALDENSTORM MACROGLOBULINEMIA? |
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Definition
| IgM AND HYPERVISCOUS (M FOR MACRO, N' m UPSIDE DOWN IS WALDENSTORM) |
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Term
| WHAT IS MONOCLONAL GAMMOPATHY OF UNDERTERMINED SIGNIFICANCE? |
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Definition
| OLD PERSON WITH GAMMA SPIKE*** GAMMA SPIKE ALSO MULTIPLE MYELOMA |
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Term
| WHAT IS MULTIPLE MYELOMA? |
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Definition
| SERUM M PROTEIN, IgG, URINE BENCE-JONES PROTEIN, ROULEUX, PUNCHED OUT LESIONS, KAPPA LIGHT CHAINS |
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Term
|
Definition
|
|
Term
|
Definition
| KID WITH ECZEMA, SKULL LESIONS, DIABETES INSIPIDUS, AND EXOPHTHAMOS |
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Term
|
Definition
|
|
Term
|
Definition
| ON SURFACE OF CELL - HEMOLYTIC ANEMIA |
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Term
|
Definition
|
|
Term
| WHAT IS TYPE N' CROSS BLOOD MATCH? |
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Definition
| PT BLOOD MATCH, READY FOR US, GOING TO SURGERY |
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Term
| WHAT IS TYPE N' MATCH BLOOD MATCH? |
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Definition
| TYPE THE BLOOD TYPE N' WAIT, JUST CHILLING ON THE SIDE |
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Term
|
Definition
| USES AB TO DETECT AG, "fabULOUS" |
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|
Term
|
Definition
|
|
Term
| WHAT DOES BLOOD A TELL YOU? |
|
Definition
| ANTIGEN FOR A, AB FOR TYPE B |
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Term
| WHAT DOES TYPE O TELL YOU? |
|
Definition
| NO ANTIGENS, UNIVERSAL DONOR |
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|
Term
| WHAT DOES TYPE AB TELL YOU? |
|
Definition
| HAVE BOTH ANTIGENS, SO RECOGNIZED BY BOTH BLOOD TYPES, SAVE TO BE UNIVERSAL RECIPIENT IN BLOOD EXCHANGE |
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Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| WHAT IS HEMOLYTIC DISEASE OF NEWBORN |
|
Definition
| Rh - MOM'S PLACENTA TEARS, 100CC OF BABY BLOOD SEES MOM/PRODUCES AB, ATTACKS FETUS!!! |
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Term
|
Definition
| SHOT GIVEN TO HELP WITH PREVENT HEMOLYTIC DISEASE OF NEWBORN - ANTI-D IgG |
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Term
|
Definition
| AT 28WKS FOR FIRST DOSE, THEN 72HRS POST DELIVERY (Rh+BABY) |
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Term
|
Definition
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|
Term
|
Definition
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|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| WITHIN HOURS, PREFORMED ANTIBODIES, ORGAN SWELLING - TAKE IT BACK OUT |
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Term
|
Definition
| THE ONLY ONE WE'LL KEEP IN THE PT WITH TREATMENT - 4 DAYS TO YEARS LATER - T CELLS AND MACROPHAGES - CELL MEDIATED IMMUNITY GOT A WHIFF OF IT |
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Term
|
Definition
| GOTTA TAKE IT OUT SOONER OR LATER, FIBROBLAST, YOU'LL SEE CALCIFICATIONS |
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Term
|
Definition
| THAT ONE LONE GUNMAN OF A LEUKOCYTE REMAINING FROM THE DONOR JUST GOES OUT LIKE RAMBO LOOKING FOR REVENGE!! - BONE MARROW TRANSPLANT REJECTION, Tk and MACROPHAGES |
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|
Term
| WHAT IS IMMUNOPRIVLEGED SITE? |
|
Definition
| WELL NOT ACTUALLY A GOOD THING IN DISEASE AFFECTED STATE, BUT GOOD FOR DONATE/TRANSPLANTS - NO LYMPHATIC FLOW - NO ANTIGENS SO EASY TRANSPLANT (BRAIN, CORNEA, THYMUS, TESTES - NOTE HEART NOT LISTED NEED >60 HLA TYPING MATCH, ITS VERY UN-IMMUNOPRIVLEGED) |
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Term
|
Definition
| MEASURED PT (DIVIDED BY) / CONTROL PT |
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|
