Term
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Definition
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Term
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Definition
Sudden onset
A lot of blasts
Most commonly found in children aged 2-5
2 Types (AML and ALL)
Mild-severe anemia
Decreased platelets
Variable WBC count
Hypercellular bone marrow
<30% blasts in the bone marrow
Auer Rods |
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Term
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Definition
Found in adults aged 50+
Less aggressive
Insidious Onset
2 Types (CML and CLL)
Mild anemia
Decreased platelets
Increased WBC count |
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Term
| Myeloproliferative Disorders |
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Definition
Non-malignant
Pancellular bone marrow
Named according to which cell line is increased the most
4 Subtypes
-Chronic Granulocytic Leukemia
-Polycythemia Vera
-Essential Thrombocythemia
-Agnogenic Myeloid Metaplasia (AMM)
Shift to the left
Hypercellular bone marrow
<30% blasts for FAB
<20% blasts for WHO |
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Term
| Myelodysplastic Syndromes |
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Definition
Cell lines are less productive
Hypocellular bone marrow
Cytopenia and dysplasia in the blood due to ineffective hematopoiesis
5 Subtypes
-Refractory Anemia
-Refractory Anemia with Ringed Sideroblasts
-Refractory Anemia with Excess Blasts
-Refractory Anemia with Excess Blasts in Transformation
-Chronic Myelomonocytic Leukemia
Hypercellular bone marrow
<30% blasts for FAB
<20% blasts for WHO |
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