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Hematology
Rbcs, Wbcs
50
Veterinary Medicine
Undergraduate 3
01/21/2014

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Cards

Term
Mean corpuscule volume
Definition
Avg size of red blood cell
Term
Mean cell hemoglobin
Definition
Avg Amt of hemoglobin in red blood cells
Term
What is the most important cause of anemia?
Definition
Lack of production
Term
Top 3 causes of anemia
Definition
Blood loss (trauma, HBC)
Hemolysis (autoimmune dz)
Lack of production
Term
Normal WBC
Definition
6,000 - 16,000
Term
Where Do RBC and WBC originate
Definition
Bone marrow
Term
What is the relative leukocyte count
Definition
A percentage
Term
What is the absolute leukocyte count
Definition
A total count
Term
What are the granulocytes
Definition
Neutrophils, eosinophils, basophils
Term
What are the agranulocytes
Definition
Lymphocytes, monocytes
Term
Percentages of granuloctyes that are visible on a blood smear
Definition
Neutrophils 70%
Eosinophils 5%
Basophils 0%
Term
Percentages of agranulocytes that are visible on a blood smear
Definition
Lymphocytes 20%
Monocytes 5%
Term
What is a nucleated RBC called
Definition
Metarubricyte
Term
How can you tell if an animal is dehydrated on a CBC
Definition
Increased PCV and a normal RBC
Term
What are the red blood cell parameters
Definition
PCV
RBC
Hemoglobin determination
Red cell morphology on blood film
Term
What is included in a CBC
Definition
RBC
WBC
Differential cell count
Hematocrit (HTC, PCV)
Total protein
Term
Functions of blood in the circulatory system?
Definition
Transport o2 and co2
Transport nutrients and waste
Controls h2o content and ph
Maintains normal body temperature
Hormones
Immunity
Coagulation
Term
Normal ph of blood
Definition
7.3
Term
What is h2co3
Definition
Carbonic acid
Term
K9 or Fel urine has what ph?
Definition
6 - 7
Term
Normal total protein
Definition
6 - 7.5 g/dl
Term
Normal k9 PCV
Definition
45%
Term
Normal Fel PCV
Definition
37%
Term
Formula to find the hemoglobin estimate?
Definition
PCV / 3 = Hb
Term
Formula to find the RBC estimate?
Definition
PCV / 6 = RBC estimate
Term
Normal RBC count
Definition
6 - 7 million
Or
6 x 10 to the 6th - 7 x 10 to the 7th
Term
Irregular, spiculated red cells with few unevenly distributed surface projections of various length and diameter
Definition
Acanthocyte/Spur Cell
Term
An antibody coats the erythrocyte causing bridging and clumping
Definition
Agglutination
Term
A variation in the size of RBC, may be due to the presence of macrocytes, microcytes or both
Definition
Anisocytosis
Term
Presence of small, dark-blue bodies within the erythrocyte; observed in cells containing residual RNA
Definition
Basophilic Stippling
Term
RBC changes from a disc shape to spheres with projections; Result of pH change due to slow drying of blood films
Definition
Crenation
Term
Tear-shaped RBC that disrupts the bone marrow architecture
Definition
Darocyte
Term
Discoid-shaped RBC, seen normally in dogs
Definition
Discocyte
Term
Spiculated cells with numerous short, evenly spaced, blunt to sharp surface projections with uniform size and shape
Definition
Echinocyte/Burr Cells
Term
A dead cell where the outside remains visible but the nucleus and cytoplasmic structures are not stainable
Definition
Ghost Cells
Term
Round structures representing denatured hemoglobin caused by certain oxidant drugs/chemicals; up to 5% normal in cats
Definition
Heinz Bodies
Term
Basophilic nuclear remnants seen in young erythrocytes in response to anemia; removed by spleen
Definition
Howell Jolly Bodies
Term
Decreased staining intensity due to insufficient hemoglobin; usually seen with iron deficiency
Definition
Hypochromia
Term
Spiculated red cells with two or more pointed projections
Definition
Keratocytes
Term
RBC's that are larger than normal with an increased MCV; usually reticulocytes
Definition
Macrocyte
Term
RBC's with a smaller than normal diameter and decreased MCV; seen in iron deficiency
Definition
Microcytes
Term
Cells released into circulation early during anemia; normal in non-mammalian animals
Definition
Nucleated RBC
Term
Abnormally shaped RBC
Definition
Poikilocyte
Term
RBC that exhibit a bluish tint when stained with Wright's stain; organelles remain in cytoplasm indicating young cells
Definition
Polychromasia/Polychromatophilic
Term
A grouping of erythrocytes in stacks; seen with increased fibrinogen or globulin
Definition
Rouleaux
Term
RBC fragments; usually from shearing of the red cell by intravascular trauma; DIC
Definition
Schistocyte/Shizocyte
Term
Erythrocytes with one or more surface projections
Definition
Spiculated Cells
Term
Darkly staining red cells with reduced or no central pallor; not easily detected except in dogs; suggest IMHA
Definition
Spherocyte
Term
Erythrocyte with an oval-shaped central pallor
Definition
Stomatocyte
Term
Thin erythrocytes with increased membrane or decreased volume
Definition
Target Cell/Leptocyte/Codocyte
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