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hematology
thrombocytes, hemostasis, plasma platelets
30
Physiology
11th Grade
02/10/2008

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Term
megakaryocytes
Definition

very large cells which blood platelets are fragments of

Term
Normal Platelet Count
Definition
130,000-400,00 per mm^3
Term
hemostasis
Definition
the stopage of bleeding
Term

Three steps of hemostasis

Definition

1) blood vessel spasm

2) Platelet plug formation

3) blood coagulation

Term
Platelet adhesion
Definition
platelets stick to the exposed collagen of damaged blood vessels
Term
platelet activation
Definition
occurs and causes platelet aggregation
Term
platelet plug is most effective on ___
Definition
small vessel
Term

Most effective means of hemostasis

Definition
coagulation
Term
major even in blood clot formation is the conversion of ____ ____  into ____ _____
Definition
souble fibrinogen, insoluble fibrin
Term
Damage tissues release ____ ____ which activates the first series of factors leading to the production of _____ activator
Definition
tissue thromboplastin, prothrombin
Term
Prothrombin activator converts__ into ___ which in turn catalyzes a reaction that converts ____ into ____
Definition
prothrombin, thrombin, fibrinogen, fibrin
Term
Fibroblasts
Definition
invade area after clot forms and produce fibers throughout the clots
Term

thrombus

Definition
clot that forms abnormally in a vessel
Term

embolus

Definition
clot that dislodges
Term
Hemophilia A
Definition
lacks factor VIII, sex linked
Term
Hemophilia B
Definition
lacks factor IX, sex-linked
Term
Hembophilia C
Definition
lacks factor XI, not sex linked
Term
Function of blood plasma
Definition
transport nutrients and gases, regulate fluid and electrolyte balance, maintain a favorable pH
Term
Albumins
Definition
help maintain the osmotic pressure of the blood and account for 60% of the plasma proteins
Term

globulins

Definition

-comprises 36% of the plasma protein

Term
alpha and beta globulins
Definition
function in transportin lipids and fat soluble vitamins
Term
gamma globulins
Definition
a type of antibody
Term
fibrinogen
Definition

-only 4% of the plasma proteins

-plays a primary role in blood coagulation

Term
Plasma nutrients include [4]
Definition
amino acids, monosaccharides, nucleotides, lipids
Term
Nonproteins Nitrogenous Substances [3]
Definition
amino acids, urea, and uric acid
Term
By products of proteiin and nuclei acid catabolism
Definition
urea and uric acid
Term
plasma electrolytes
Definition
-absorbed by the intestine or by-products of cellular metabolism
Term
8 plasma electrolytes
Definition
sodium, potassium, calcium, magnesium, chloride, bicarbonate, people, sulfate
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