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Hematology
White Blood Cell Disorders
20
Medical
Undergraduate 1
09/12/2011

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Term
Autoimmune Neutropenia
Definition
Auto antibodies directed against neutrophils have been detected in the serum of some patients with Neutropenia of idiopathic origin.
Term
Isoimmune Neonatal Neutropenia
Definition
It has been characterized in infants with severe neutropenia to be analogous to Rh isoimmunie hemolytic anemia.
Term
Drug-Induced Neutropenia
Definition
Pharmacologic compounds are recognized to cause disorders in neutrophils numbers and functions.
Term
Severe Congenital Neutropenia
Definition
is a rare autosomal recessive disorder with chronic neutrophil counts of less than 0.2 X 109/L
Term
Chronic Benign Neutropenia
Definition
is a heterogeneous group of disorders associated with neutrophil counts of fluctuate from 0.2 to 2.0 X 109/L
Term
Cyclic Neutropenia
Definition
It is a rare neutropenic condition that is noted for cyclic fluctuations in the neutrophil count.
Term
Chemotaxis disorder of Neutrophil
Definition
Abnormal mobilization related to an intrinsic neutrophil defects, cell directed inhibitors, chemotaxic factor directed inhibitors or undefined mechanisms
Term
Myeloperoxidase Deficiency
Definition
During normal phagocytosis, this enzyme mediates the conversion of superoxide anion and hydrogen peroxide to more toxic killing agents
Term
Chediak Higashi Syndrome
Definition
autosomal recessive condition characterized by partial albinism of the cutaneous and ocular tissues.
Term
Chronic Granulomatous Disease
Definition
the congenital abnormality is associated with a failure in the activation of the respiratory burst which results in little or no superoxide production
Term
Hypersegmentation
Definition
the number of segmented lobes demonstrated in the mature neutrophil is more than six nuclear lobes
Term
Pelger Huet anomaly
Definition
the nucleus is found to be bilobed or to have no lobulation
Term
Acute eosinohilic leukemia
Definition
is a rare subtype of acute myeloid leukemia with 50 to 80 percent of eosinophilic cells in the blood and marrow. It can arise de novo or may develop in patients having the chronic form of a hypereosinophilic syndrome.
Term
Acute lymphoblastic leukemia
Definition
is a form of leukemia, or cancer of the white blood cells. Malignant, immature white blood cells continuously multiply and are overproduced in the bone marrow. ALL causes damage and death by crowding out normal cells in the bone marrow, and by spreading (metastasizing) to other organs.
Term
Acute myeloid leukemia
Definition
is a cancer of the myeloid line of white blood cells, characterized by the rapid proliferation of abnormal cells which accumulate in the bone marrow and interfere with the production of normal blood cells.
Term
Acute promyelocytic leukemia
Definition
a cancer of the blood and bone marrow. It is also know as acute progranulocytic leukemia; APL; AML
Term
Adult T cell leukemia (ATL)
Definition
is a rare cancer of the immune system's own T-cells. Human T cell leukemia/lymphotropic virus type 1 (HTLV-1) is believed to be the cause of it, in addition to several other diseases.
Term
Agranulocytosis
Definition
is an acute condition involving a severe and dangerous leukopenia (reduction in the number of white blood cells) in the body
Term
Chronic neutrophilic leukemia
Definition
is a rare myeloproliferative disorder that features a persistant neutrophilia in peripheral blood, myeloid hyperplasia in bone marrow
Term
Autoimmune neutropenia
Definition
is a form of neutropenia which is most common in infants and young children where the body identifies the neutrophils as enemies and makes antibodies to destroy them.
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