Term
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Definition
Iron chelator
-acute iron poisoning
-hemochromatosis
IntraM or SubQ |
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Term
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Definition
treatment for iron deficiency
oral or parenteral
no method for excretion; acute overdose (mostly in children) necrotizing gastroenteritis, ab pain, bloody diarrhea, shock |
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Term
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Definition
oral iron preparation
treatment for iron deficiency |
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Term
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Definition
parenteral iron preparation
IV or deep IntraM
allergic rxn possible |
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Term
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Definition
parenteral iron preparation
IV only
less chance of allergic rxn |
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Term
| iron sodium gluconate complex |
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Definition
parenteral iron preparation
IV only
less chance of allergic rxn |
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Term
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Definition
treats vitamin B12 deficiency, duh
-parenteral req for pernicious anemia and malabsorption
-no toxicity |
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Term
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Definition
parenteral B12
ItraM injections every other day 1-2wks
maintenance: 1/month |
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Term
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Definition
parenteral B12
*preferred bc more highly protein bound and remains in circulation longer
ItraM injections every other day 1-2wks
maintenance: 1/month |
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Term
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Definition
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Term
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Definition
treats folate deficiency
no toxicity, but can mask vitB12 def
oral
richest dietary sources: yeast, liver, kidney, green vegetables, fortified grains |
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Term
erythropoietin
(epoetin alpha) |
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Definition
stimulates erythroid proliferation, release of reticulocytes from BM
-treat anemia caused by: renal failure, HIV, cancer
IV or SubQ 1-3x/wk
tox: high bp, thrombotic complications |
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Term
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Definition
glycosylated from of erythropoeitin
long lasting
IV or subQ 1x/wk |
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Term
Oprelvekin
(interleukin-11) |
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Definition
stimulates megakaryocyte progenitors --> increases platelet numbers
activates IL-ll receptors
-prevents throbocytopenia in chemo pt
daily by subQ injection |
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Term
|
Definition
stimulates megakaryocytes
genetically engineered protein: Romiplostim, still being researched
-used for ITP |
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