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Hematology Internship Section 3
Coagulation/Hemostasis Coagulation Tests. Page 97
29
Biology
Undergraduate 4
10/14/2015

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Term
Given the Principle, Name the Coagulation Test associated with it:

Latex particles coated with FSP fragments D & E
Definition
Fibrin split products / Fibrin degradation products
(FSP or FDP)
Term
Given the Principle, Name the Coagulation Test associated with it:

Measures a specific fragment from cross-linked fibrin and therefore is POSITIVE ONLY IN Secondary Fibrinolysis
Definition
D-Dimer
Term
Given the Principle, Name the Coagulation Test associated with it:

A small puncture wound is made in the patient's forearm. The time from the puncture until the time the blood ceases for form a drop on filter paper is measured.
Definition
Bleeding Time
Term
Which Coagulation Test measures products only from a blood clot and NOT from breakdown of circulating fibrinogen?
Definition
D-Dimer
Term
What is another name for cross-linked fibrin?
Definition
D-Dimer
Term
What is Bleeding Time a rough estimate of?
Definition
Platelet and vascular function.
Term
How will the Bleeding Time Test be affected in platelet count is low?
Definition
It will be prolonged
Term
What is the reference range for the following Coagulation Test:

FSP / FDP
Definition
Less than 10 micrograms/mL
Term
What is the reference range for the following Coagulation Test:

D-Dimer
Definition
Less than 200 nanograms/mL
Term
If D-Dimer is NEGATIVE & FSP is POSITIVE, what does the patient have?
Definition
Primary fibrinogenolysis
Term
What is the reference range for the following Coagulation Test:

Bleeding Time
Definition
2-9 minutes
Term
True or False:
The Bleeding Time test is NOT valid if the platelet count is LOW
Definition
True
Term
What are the factors measured for the following Coagulation Test:

FSP or FDP
Definition
FSP D & E
Term
What are the factors measured for the following Coagulation Test:

D-Dimer
Definition
Only cross-linked fragments
Term
What are the factors measured for the following Coagulation Test:

Bleeding Time
Definition
Platelet Function
Term
What will D-Dimer NOT Measure?
Definition
FSP D, E, X, or Y
Term
True or False:
D-dimer is POSITIVE ONLY IN Secondary Fibrinolysis and NOT in Primary Fibrinolysis
Definition
True
Term
What are 2 types of Secondary Fibrinolysis?
Definition
DIC & Blood Clots
Term
What Test is POSITIVE in DIC, Embolisms, Phlebitis, and Thrombosis?
Definition
D-Dimer
Term
Is D-Dimer POSITIVE or NEGATIVE in DIC, Embolisms, Phlebitis, and Thrombosis?
Definition
Positive
Term
What diseases are detected through FSP / FDP?
Definition
DIC, Thrombosis, and Primary Fibrinogenolysis
Term
With the FSP/FDP Test, where is the rare disorder where Plasmin is INCREASED usually from?
Definition
Tumor at plasminogen activator production sire
Term
With the FSP/FDP Test, what does the rare disorder where Plasmin is INCREASED cause?
Definition
Causes Plasmin to attack circulating fibrinogen
Term
In what disorders will the Bleeding Time be Prolonged?
Definition
Platelet function such as von Willibrand, Bernard-Soulier, Glanzmann Disorder, and Aspirin Ingestion.
Term
Given the following Special Notes, Name the Coagulation Test that it is associated/given with/for:

Draw blood in tube with EXCESS Thrombin to assure no fibrinogen is left and the clotting is complete. Also, add a trypsin inhibitor to prevent In Vitro fibrinolysis
Definition
Fibrin Split Products / Fibrin Degradation Products
(FSP or FDP)
Term
Given the following Special Notes, Name the Coagulation Test that it is associated/given with/for:

Run on plasma to eliminate False Positive
Definition
D-Dimer
Term
Given the following Special Notes, Name the Coagulation Test that it is associated/given with/for:

Are many technical variables. Must be performed with strict adherence to the procedure by trained personnel. Interpretation should be in conjunction with patient's history.
Definition
Bleeding Time
Term
True or False:
D-Dimer is MORE SPECIFIC for DIC or Thrombosis than is FSP
Definition
True
Term
What has the Bleeding Time Test been replaced by?
Definition
Platelet Function Test
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