Term
Given the Anticoagulant Action, Name the Anticoagulant:
Interferes with production of Vitamin K factors; Takes 36-72 hours to work |
|
Definition
|
|
Term
True or False:
Coumadin/Warfarin can NOT be used on pregnant women |
|
Definition
|
|
Term
Given the Anticoagulant Action, Name the Anticoagulant:
Inhibits formation of thromboxane A2 and therefor platelet aggregation |
|
Definition
|
|
Term
Given the Anticoagulant Action, Name the Anticoagulant:
Combines with AT and Rapidly Inhibits Thrombin (IIa) and Xa, XIIa, XIa, and IX a, stopping clotting. |
|
Definition
| Heparin / Standard unfractionated heparin (UFH) |
|
|
Term
Given the Anticoagulant Action, Name the Anticoagulant:
Binds to AT but inhibits only Xa and NOT thrombin |
|
Definition
| Low Molecular Weight Heparin (LMWK) |
|
|
Term
Given the Anticoagulant Action, Name the Anticoagulant:
Cause plasminogen to convert to plasmin which Breaks Down the Clot |
|
Definition
Streptokinase or Urokinase
"Clot Busters" |
|
|
Term
Given the Anticoagulant Action, Name the Anticoagulant:
Breaks up existing Clot
Works only on clotted surface so does not cause systemic bleeding |
|
Definition
t-PA
Tissue plasminogen activator
"Clot Busters" |
|
|
Term
| Which "Clot Buster" causes plasminogen to convert to plasmin, thus breaking down the clot? |
|
Definition
| Streptokinase or Urokinase |
|
|
Term
| Which "Clot Buster" ONLY works on clotted surfaces? |
|
Definition
|
|
Term
| Which "Clot Buster" does NOT cause systemic bleeding? |
|
Definition
|
|
Term
Given the anticoagulant, name the pathway with which it is involved:
Coumadin/Warfarin |
|
Definition
| Mostly EXTRINISIC, but some effect on Intrinsic and PTT because of factor IX |
|
|
Term
Given the anticoagulant, name the pathway with which it is involved:
Aspirin |
|
Definition
|
|
Term
Given the anticoagulant, name the pathway with which it is involved:
Heparin / Standard unfractionated heparin (UFH) |
|
Definition
|
|
Term
Given the anticoagulant, name the pathway with which it is involved:
Low Molecular Weight Heparin (LMWH) |
|
Definition
|
|
Term
Given the anticoagulant, name the pathway with which it is involved:
Streptokinase or Urokinase "Clot Busters" |
|
Definition
|
|
Term
Given the anticoagulant, name the pathway with which it is involved:
t-PA / Tissue plasminogen activator
"Clot Buster" |
|
Definition
|
|
Term
| Though Coumadin/Warfarin is mostly involved in the EXTRINSIC pathway, what factor causes it to have some effect on INTRINSIC and PTT? |
|
Definition
|
|
Term
| Overdose of Heparin is treated with what and why? |
|
Definition
| Protamine Sulfate, because it inactivates heparin |
|
|
Term
| Which "Clot Buster" is Non-fibrin specific so there is MORE danger of bleeding (can attack fibrinogen)? |
|
Definition
| Streptokinase or Urokinase |
|
|
Term
Which factors are affected by the following anticoagulant:
Coumadin/Warfarin |
|
Definition
| Vitamin K factors: II, VII, IX, X |
|
|
Term
Which factors are affected by the following anticoagulant:
Aspirin |
|
Definition
|
|
Term
Which factors are affected by the following anticoagulant:
Heparin / Standard unfractionated heparin (UFH) |
|
Definition
| Thrombin (IIa) and Xa mostly, but also XIIa, XIa, and IXa. |
|
|
Term
Which factors are affected by the following anticoagulant:
Low Molecular Weight Heparin (LMWH) |
|
Definition
|
|
Term
Which factors are affected by the following anticoagulant:
Streptokinase or Urokinase |
|
Definition
|
|
Term
Which factors are affected by the following anticoagulant:
t-PA / Tissue Plasminogen Activator |
|
Definition
|
|
Term
| With Coumadin/Warfarin, which factor is affected FIRST? |
|
Definition
|
|
Term
True or False:
Many drugs and lifestyle habits interfere with Coumadin/Warfarin drug action |
|
Definition
|
|
Term
True or False:
Heparin does NOT work properly if patient has AT deficiency? |
|
Definition
|
|
