Term
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Definition
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Term
anticoagulant in pregnancy |
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Definition
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Term
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Definition
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Term
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Definition
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Term
advantage of LMW heparins |
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Definition
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Term
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Definition
heparin binds factor 4, causing ab production that binds to and activates platelets, leading to their clearance and resulting in a thrombocytopenic, hyper coagulable state |
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Term
used in patients with HIT |
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Definition
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Term
direclty inhibit thrombin |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
teratogenic, bleeding, skin/tissue necrosis |
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Term
Hep vs warfarin: small lipid soluble |
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Definition
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Term
Hep vs warfarin: large, anionic |
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Definition
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Term
Hep vs warfarin: parenteral |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
Hep vs warfarin: acute onset |
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Definition
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Term
Hep vs warfarin: chronic onset |
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Definition
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Term
Hep vs warfarin: crosses placenta |
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Definition
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Term
|
Definition
streptokinase, urokinase, tPA and anistreplase |
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Term
convert plasminogen to plasmin |
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Definition
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Term
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Definition
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Term
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Definition
active bleeding, intracranial bleed, recent surgery, bleeding diatheses, or severe hypertension |
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Term
|
Definition
vinca alkaloids and taxols |
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Term
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Definition
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Term
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Definition
etopside, antimetabolites |
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Term
inhibit nucleotide synthesis |
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Definition
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Term
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Definition
alkylatig agents, cisplatin dactomycin, doxorubicin, etopside |
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Term
inhibit cellular division |
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Definition
vinca alkaloids, paclitaxel |
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Term
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Definition
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Term
leukemias, lymphomas, choriocarcinoma and sarcomas |
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Definition
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Term
abortion, ectopic pregnancy, RA, psoriasis |
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Definition
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Term
reversible with leucovorin |
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Definition
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Term
fatty liver change, mucositis, teratogenic |
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Definition
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Term
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Definition
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Term
inhibits thymidylate synthase |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
metabolized by xanthine oxidase |
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Definition
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Term
bone marrow depression, liver |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
antitumor abx that intercalates DNA |
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Definition
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Term
wilm's tumor, ewing, rhabdomyosarcima |
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Definition
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Term
generates free radical -> noncovalently intercalate in DNA |
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Definition
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Term
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Definition
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Term
how prevent cardiotoxicity with doxorubicin? |
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Definition
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Term
free radical formation -> breacks in DNA |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
inhibits topoisomerase II |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
busulfan, imanitib, hydroxyurea |
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Term
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Definition
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Term
inhibits microtubule assembly |
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Definition
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Term
wilm's choriocarcinoma, ALL |
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Definition
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Term
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Definition
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Term
MT inhibitor with myelosuppression |
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Definition
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Term
inhibits tubulin disassembly |
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Definition
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Term
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Definition
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Term
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Definition
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Term
how prevent nephrotoxicity with cisplatin? |
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Definition
amifostine and chloride diuresis |
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Term
inhibits ribonucleotide reductase |
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Definition
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Term
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Definition
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Term
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Definition
cushing like, immunosuppression, cataracts, acne, osteoporosis, HTN, peptic ulcers, hyperglycemia and psychosis |
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Term
blocks biding of estrogen to estrogen receptors |
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Definition
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Term
may increase risk of endometrial cancer |
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Definition
tamoxifene; NOT raloxifene |
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Term
monoclonal ab to Her-2 neu |
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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