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the average amount of energy deposited per unit length of track |
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X-rays and gamma rays are streams of moving particles known as photons, which have no mass or charge. |
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When low-LET radiation interacts with biological tissue, it typically causes cell destruction by an indirect action that includes the synthesis of chemicals. |
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a double-strand break in the same rung of the DNA ladder-like structure |
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Relative biologic effectiveness |
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the comparative ability of radiation with varying LETs to generate a certain physiological response |
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due to the presence of oxygen, to the amplification of the therapeutic or harmful action of ionizing radiation. |
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Biologic damage happens as a result of atom ionization on vital molecules caused by a direct contact with incoming radiation. |
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is always a multistage process that begins with the generation of free radicals, which are often produced by the interaction of radiation with water (H2O) molecules. |
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the dissociation of molecules by ionizing radiation. |
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the notion of radiation harm to certain sensitive areas caused by discrete and random occurrences |
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Non-mitotic, or non-divisional, cell death occurs when cells die without attempting division during the interphase phase of the cell life cycle. |
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The traditional way of demonstrating the susceptibility of a certain kind of cell to radiation. |
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Law of Bergonié and Tribondeau |
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Cell radiosensitivity is related to their reproductive activity and inversely proportional to their degree of differentiation. |
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The strict sequence of these bases contains genetic information that will be handed down to future generations; the removal or modification of a base in the DNA chain |
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harms biological systems by removing electrons from (ionizing) the atoms that make up their chemical structures |
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When a volume is irradiated with an x-ray or gamma ray dosage of around 1000 Gyt in seconds or minutes, a huge number of cells are produced. |
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occurs when a cell dies after one or more divisions. |
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the cell's inability to begin dividing on time |
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Cells are usually exposed to doses of ionizing radiation ranging from 1 to 10 Gyt. |
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Radiation weighting factor |
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Definition
used to compute the equivalent dose of any kind of ionizing radiation to estimate its capacity to produce biologic damage |
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