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Heart, Death and Dying, and Cancer
Vocabulary and questions about the heart, death and dying, and cancer.
112
Biology
Undergraduate 3
05/04/2011

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Term
What is plasma?
Definition
The fluid portion of the blood
Term
Packed cell transfusion
Definition
giving the cells
Term
red blood cells
Definition
carry oxygen and carbon dioxide
Term
white blood cells
Definition
fight infection
Term
platelits
Definition
involved in clotting
Term
closed system
Definition
circulates around and around; break causes damage
Term
What type of arteries keep blood flowing?
Definition
open
Term
Plaque buildup causes blood vessels to become ---- in diameter, which in turn causes ---- blood pressure.
Definition
smaller, high
Term
What are the top two chambers of the heart called?
Definition
atria
Term
What do the atria do?
Definition
entrance area; receive the blood
Term
Where are the ventricles located, and what do they do?
Definition
bottom; side by side; pump blood
Term
After the blood enters the heart from the top of your body, where does it go?
Definition
superior vena cava
Term
What is the superior vena cava and what does it do?
Definition
top "big vein"; goes into right atrium
Term
What is inferior vena cava?
Definition
brings blood from trunk and legs up to heart; brings to right atrim:
Term
What is the tricuspid valve?
Definition
type of atria-ventricle valve at the bottom of right atrium; flows down into right ventricle.
Term
Where does the right ventricle pump blood?
Definition
to lungs
Term
From the right ventricle, blood goes where?
Definition
back into left atrium
Term
What is the mitral valve?
Definition
pumps out blood to rest of body
Term
What is a heart murmur?
Definition
happens when tricuspid or mitral valve don't close all the way; backwash
Term
How is blood pressure written?
Definition
cystalic diastalic
Term
What is the cystalic number?
Definition
pressure when heart's pumping to lungs and rest of body
Term
What is diastalic?
Definition
the number that measures how much your heart relaxes
Term
What is "normal" blood pressure?
Definition
120/80 (high end)
Term
What is hypertension?
Definition
high blood pressure; usually develops over time
Term
What causes high blood pressure?
Definition
heredity, diet, decreased activity, genes
Term
Athrosclorosis
Definition
heart disease; refers to health of heart itself
Term
coronary arteries
Definition
arteries that feed the heart
Term
LDL
Definition
cholesterol and protein deposited
Term
HDL
Definition
cholesterol and protein broken down by body
Term
embolis
Definition
moving clot
Term
saturated fats
Definition
fats that come from animals and are solid in the fridge
Term
angioplasty
Definition
Docs put int fiborous "balloon" to hold artery open
Term
coronary bipass
Definition
severe cases; leave blockage in, but work around it with saphenous leg veeins; reroute bloodflow
Term
What protein is responsible for ovary cancer?
Definition
CA 125
Term
metastatic
Definition
leave original place and move around body
Term
Characteristics of cancer cells
Definition
abnormal in appearance and action
metastatic
multiply indefinitely
not controlled by normal metabolic processes
Divide uncontrolably
Term
angiogenesis
Definition
new circulation
Term
Difference between cancer and tumor
Definition
cancer disrupts body function; tumor mass of cells with no function
Term
cancer
Definition
group of diseases characterized by uncontrolled growth and spread abnormal cells
Term
benign tumor
Definition
noncancerous; no effect on cells around--encapsulated
Term
malignant
Definition
cancerous; tumor invades surrounding tissue
Term
apoptosis
Definition
cell death
Term
How does cancer work?
Definition
unregulated cell growth; abnormal cells not destroyed
Term
What happens during metastatic cancer?
Definition
Cells break away; cells on edge of tissue break off into circulatory and other system and into body
Term
Primary v. secondary tumor
Definition
where it started--primary; where it goes--secondary
Term
What are normal CA 125 levels?
Definition
35
Term
carsonomas
Definition
cancers that affect epithial tissue and linings; ex: skin, stomach, intestine, uterus, esophagus
Term
carcoma
Definition
cancer associated with connective tissue; ex: tendons, bone, muscle, liver, kidneys
Term
leukemia
Definition
general term describing cancers of the blood; also applies to bone marrow tissue, spleen, lymph
Term
recurrance
Definition
coming back after treatment
Term
remission
Definition
cancer not dividing
Term
Genes responsible for ovarian cancer also associated with:
Definition
breast cancer; brca 1 and brca 2
Term
How many genes generally involved in cancer?
Definition
6-9
Term
cancer treatments
Definition
surgery; radiation; kemotherapy
Term
What are breast and ovarian cancer drugs made from?
Definition
Tree called taxis; Taxol
Term
mammogram or self-exam
Definition
breast cancer
Term
pap smear
Definition
cervical
Term
blood in stool, colonoscopy
Definition
colon cancer
Term
prostate exam, blood screening called psa, EPCA 2
Definition
prostate cancer
Term
discoloration, sores that won't heal, moles that change color
Definition
skin cancer
Term
self-exam
Definition
testicular cancer
Term
How many types of cancer?
Definition
at least 200
Term
Most common type of cancer?
Definition
skin
Term
Number one cancer killer
Definition
lung
Term
skin cancer is also called
Definition
melanoma
Term
Skin cancer most common in what ages?
Definition
25-29
Term
Gene associated with skin cancer
Definition
P53, which controls cell phase
Term
Skin cancer develops most where you've been exposed because:
Definition
Melanin creates more when exposed, which can cause gene mutation
Term
Lung cancer diagnosed at later stages because:
Definition
very slow growth rate
Term
TF: screening test for lung cancer is self-exam
Definition
F: no test
Term
In lung cancer, it's better to have a ---- than a ----.
Definition
nonsmall cell; small cell carconoma
Term
Treatment for lung cancer
Definition
surgery, kemo, radiation
Term
What is the PSA?
Definition
prostate cancer; protein produced by cells of the prostate gland; prostate-specific antigen; normal 0 ng/ml to 4 ng/ml
Term
signs symptoms of prostate cancer
Definition
urine hesitancy; pain with urination; pelvic pain; blood in urine
Term
kemateria
Definition
blood in urine
Term
prostate cancer treatment
Definition
watch and wait
external radiation therapy
surgery
internal radiation therapy
cold or hot ablation
Releasing hormone blocker
Term
cervical cancer is highest in women
Definition
40 and over
Term
cervical displasia
Definition
cells that are unusual or abnormal; often in younger women
Term
What STDs is cervical cancer associated with?
Definition
HPV (Gartacil vaccine) Herpes Simplex II
Term
cervical cancer treatment
Definition
histerectomy; radiation therapy; kemotherapy; both R and K combined
Term
most common breast cancer
Definition
ductal carsonoma
Term
mastectomy
Definition
some, part, or all of one breast
Term
prophalactomy
Definition
both breasts
Term
colon cancer can appear in
Definition
colon or rectum
Term
cancer with only minimal (5-25%) genetic/family history
Definition
colon cancer
Term
self-screen for colon cancer
Definition
blood in stool
Term
Name some chars of early onset stages of Alz Heimers.
Definition
Memory loss
Brain shrinks
Lost in familiar places
Misplacing items
Difficulty learning new info
Term
Later onset of AlzHeimers
Definition
Worsening memory loss
Depression, confusion
Relying on others for decision-making
Lose awareness of here and now
Need constant care
Brain shrinks
Term
Alz Heimers associated with
Definition
Plaques: nerves cannot send message from one to another
Tangles: nerve cells intertwine
Term
Parkinson's
Definition
chronic, progressive disorder associated with group called motor system disorders
Term
Parkinson's characterized by:
Definition
shakiness or extreme fatigue
Memory lapses
Tremors or rigidity
Bad posture (cane, walker)
Dopamine-producing cells damaged or broken
Term
bradicanesia
Definition
no spontaneous, automatic movement; movement is slow
Term
Austio Perosis
Definition
"brittle bones"
Bones become holey, resulting from less structure
Calcium between bones less
Term
austio penia
Definition
change in bone mass
Term
Calcium is depositted in bones in women with this hormone
Definition
estrogen
Term
austio persois reasons
Definition
Age
Decreased estrogen during menapause
No calcium in diet
Sedetery lifestyle
Cancer and cancer treatments
Tobacco and alcohol
Kidney problems
Causes curvature of spine--kafosis
Term
Stroke is
Definition
Clot causing blockage in arteries leading to brain
Term
telemere
Definition
series of nucleotides at end of chromosomes that repeat
Get shorter with each division of mitosis
Causes genes to turn on/off
Eventually, cell death, aging, human death
Term
What enzyme adds back telemeres?
Definition
telomerase
Could be effective in understanding and curing cancer and stopping aging
Term
advance directive
Definition
general term describing in writing what you want done and not done
Verbal overrides written if you can speak
Term
Living will
Definition
Terminally ill
No one superseeds
What you want and don't want
Term
durable power of atourney for health care
Definition
someone else has responsibility for your medical decisions
Term
do not recussitate (dnr)
Definition
Can be put in living will, but a document by itself
Is overridden when calling 911
Works for hospice, hosppital stay, nursing home
Term
stem cells
Definition
unspecialized cells that retain ability to divide
Specialized cells take their place
Term
Where can stem cells come from?
Definition
Embryo
Placenta
Adults
Term
totipotent
Definition
come from ball of cells; can become anything, even placenta, aren't used much
Term
pleuripotent
Definition
come from blastosis
any type, except placenta
Term
multipotent
Definition
bone marrow
can become multiple type of cells related to blood
Term
What is Progeria?
Definition
Progeria also known as Hutchinson–Gilford syndrome is an extremely rare genetic condition wherein symptoms resembling aspects of aging are manifested
at an early age.
Term
How long do people with Progeria live?
Definition
13 years
Term
90% of patients with Progeria die of
Definition
complications of atherosclerosis, such as heart attack or stroke
Term
What is progeria caused by?
Definition
mutations in the gene coding for lamin A protein on chromosome 1
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