Shared Flashcard Set

Details

Heart
The Heart
54
Pathology
Graduate
11/09/2011

Additional Pathology Flashcards

 


 

Cards

Term
Heart Disease is the #1 cause of death worldwide, what percentage of deaths in the US are Heart Disease Related?
Definition
40%
Term
What is the normal size of heart in women?
Definition
250-300 grams
Term
What is the normal size of heart in men?
Definition
300-350 grams
Term
When does most coronary blood flow: Systole or Diastole ?
Definition
Ventricular Diastole
Term
What are some markers for CHF?
Definition
ANP and BNP (Atrial and Brain Natriuretic peptides)
Term
What is the most common cause of Left Heart failure?
Definition
Hypertension
Term
What are Heart failure cells?
Definition
Siderophages- Macrophages in the Lung that take up the blood that leaks out (stain for iron)
Term
What is the function of Atrial Natriuretic Peptide?
Definition
Decrease blood volume, released when atria dilate.
Term
What is the most common cause of Right Heart Failure?
Definition
Left Heart Failure
Term
NEck Vein Distention is associated with?
Definition
Right Heart Failure
Term
Endocardial cushion defects and AV septal defects are associated with?
Definition
Down Syndrome (trisomy 21)-Most common genetic cause of congenital heart disease
Term
What causes a left-to-right shunt to switch directions?
Definition
Eventual pulmonary hypertension reverses the shunt.
Term
What is a possible complication seen with a Right-to-left shunt such as Patent Foramen Ovale?
Definition
Paradoxical Emboli, Cyanosis, clubbing, polycythemia
Term
The severity of symptoms of Tetralogy of Fallot is based on which specific defect?
Definition
Severity of Pulmonary Stenosis
Term
How can a Patient with Pulmonary Valve Atresia survive?
Definition
Patent Ductus Arteriosus and Septal Defect
Term
Coarctation of the Aorta is associated with?
Definition
Men (2:1) and Turner Syndrome
Term
A Male child that is born is cyanotic in his lower body. What is the diagnosis?
Definition
Coarctation of the Aorta with a Patent Ductus Arteriosus
Term
A 25 year old adult male comes in for a checkup and is found to have a very weak pulse and a low Blood Pressure in his lower limbs but hypertension in his upper limbs. X-Ray shows Costal Notching. What Congenital abnormality was this man born with?
Definition
Coarctation of Aorta distal to the Arch Vessels without a patent ductus arteriosus
Term
What percent of cardiovascular deaths are due to Ischemic heart disease?
Definition
80-90%
Term
Sudden cardiac death is most likely due to?
Definition
arrhythmia
Term
Unstable angina occurs when a major heart vessel is occluded by what percent?
Definition
90% occluded
Term
Stable angina occurs when a major heart vessel is occluded by what percent?
Definition
75% occluded
Term
Prinzmetal Angina is caused by?
Definition
Vasospasm
Term
After an MI, at what point is coagulative necrosis present?
Definition
12-24 hours
Term
What is the cutoff time for thrombolytic therapy?
Definition
4 hours, damage is permanent if tissue is un/under-perfused in 2-4 hours
Term
What vascular branch is most commonly thrombosed in a MI?
Definition
LAD (40-50%)
Term
CK-MB peaks at what time?
Definition
1 day
Term
When do we no longer see elevated CK-MB levels?
Definition
3 days
Term
How long can troponin levels be elevated after an MI?
Definition
peak in 2 days and remain elevated for 7-10 days
Term
Myocardial rupture occurs most often how many days after MI?
Definition
Days 3-7 when heart is "softest"
Term
Stenosis of a valve is?
Definition
trouble "opening" with impedance of blood flow
Term
Valve insufficiency is?
Definition
Failure to close completely (regurgitation)
Term
What causes functional regurgitation?
Definition
Ventricular dilation- papillary muscles pull normal valve leaflets down and out
Term
Rheumatic Heart Disease most commonly affects which valve?
Definition
Mitral Stenosis
Term
"Acquired" bicuspid Aortic Valve results from?
Definition
Rheumatic Disease
Term
What is the largest risk with Mitral Annular Calcification?
Definition
embolization
Term
What is another name for Myxomatous Degeneration of the Mitral Valve?
Definition
Mitral Valve Prolapse
Term
Mitral Valve Prolapse is associated with what disease?
Definition
Marfan, other connective tissue diseases
Term
When a doctor listens to a patients heart, he hears a click mid systole. What is the problem?
Definition
Mitral Valve Prolapse
Term
A patient presents with Migratory Polyarthritis in his Knees then his Ankles, and he has also had uncontrolled rapid movements of his arms and legs and a fever. The patient states that he recently had a diagnosed strep infection. What is happening?
Definition
Rheumatic Fever
Term
At autopsy, a patients mitral valve shows stenosis that resembles a fish mouth or buttonhole. What is this associated with?
Definition
Chronic Rheumatic Heart Disease
Term
What is the most common overall cause of infective endocarditis?
Definition
Strep Viridans
Term
What is the most common cause of infective endocarditis in IV DRUG ABUSERS?
Definition
Staph Aureus
Term
What percent of patients die from Acute endocarditis even with treatment?
Definition
50% die in days-weeks
Term
Nonbacterial Thrombotic Endocarditis is associated with?
Definition
Mucin producing tumors of the colon or pancreas cause a procoagulative state.
Term
Libman-Sacks Endocarditis is?
Definition
Vegetations located on the underside of heart valves, associated with SLE
Term
Common cause of sudden death in young athletes?
Definition
Hypertrophic Cardiomyopathy
Term
Restrictive Cardiomyopathy can have many causes, name 2.
Definition
Amyloidosis, Sarcoidosis, Radiation, metastases
Term
What is the most common viral cause of Myocarditis?
Definition
Coxsackievirus
Term
In central and south america what is the most common cause of myocarditis whith leads to CHF?
Definition
Chagas Disease (Trypansoma Cruzi)
Term
Common cause of sudden death in young athletes?
Definition
Hypertrophic Cardiomyopathy
Term
Restrictive Cardiomyopathy can have many causes, name 2.
Definition
Amyloidosis, Sarcoidosis, Radiation, metastases
Term
What is the most common viral cause of Myocarditis?
Definition
Coxsackievirus
Term
In central and south america what is the most common cause of myocarditis whith leads to CHF?
Definition
Chagas Disease (Trypansoma Cruzi)
Supporting users have an ad free experience!