Term
| Gleptoferron / Iron dextran |
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Definition
| Iron-carbohydrate complexes used as IM inj to piglets to prevent piglet anaemia |
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Term
| Cyanocobalamin / hydroxycobalamin |
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Definition
Used for treatment of vit. B12 deficiency, which would result in anaemia (sub/cut, i/m)
(vit B12 necessary in purines / pyrimidines, which are necessary in RBCs) |
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Term
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Definition
| agents which improve the quality of blood - inc haemoglobin / no. of RBCs |
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Term
| Cobalt sulphate / chloride |
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Definition
solution put on pasture for the treatment of cobalt deficiency which can result in anaemia
-cobalt important in vit B12 which is necessary in purines / pyrimidines, which are necessary in RBCs |
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Term
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Definition
growth factor produced in kidneys which stimulates haemaopoeisis in BM
-can give as exogenous inj. if deficient / kidney dz
-lack of EPO results in anaemia due to decr. RBC production |
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Term
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Definition
vit k1 - used in vit K deficiency / warfarin poisoning
- a pro-haemostatic |
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Term
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Definition
anticoagulant, used in long term (venous) thrombosis treatment - inhibits vit K reductase and so inhibits vit k - clotting factors not carboxylated and so can not be activated and form a clot
(factors affected: II, VII, IX, X) |
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Term
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Definition
anticoagulant, used in short term (venous) thrombosis treatment
-binds and activates antithrombin III (ATIII) which inhibits IIa and ~Xa
i.e prothrombin not converted to thrombin, so clots does not form |
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Term
| Low molecular weight (LMW) heparin |
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Definition
As for heparin: anticoagulant, used in short term (venous) thrombosis tx
-binds and activates antithrombin III (ATIII) which inhibits Xa ONLY i.e. not IIa |
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Term
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Definition
An antiplatelet drug - binds and inactivates COX enzymes - reversible in endothelium but irreversible in platelets - decr. production of TXA2 which normally activates platelets
-used in arterial thrombosis in cats |
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Term
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Definition
a "clot-busting" drug
-promotes conversion of plasminogen --> plasmin, which breaks down fibrin
-currently too expensive for vet med |
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