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Growth Factors in Repair/Regen
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6
Medical
Professional
07/12/2012

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Term
mitogenic for keratinocytes and fibroblasts, stimulates granulation tissue formation
Definition
EGF
Term
similar to EGF stimulates replication of hepatocytes and epithelial cells
Definition
TGF-a
Term
chemotactic for PMNs macrophages fibroblasts and endothelial cells and smooth muscle cells

stimulates angiogeneis

stimulates wound contraction
remodeling
INHIBITS PLATELET AGGREGATION
regulates integrin expression
Definition
PDGF
Term
chemotactic for fibroblasts
mitogenic for fibroblasts and keratinocytes
stimultes angiogensis and wound contraction and matrix deposition
Definition
FGF
Term
chemotactic for PMNs, lymphocytes, macrophages, fibroblasts, and smooth msucle cells; stimulates angiogenesis and fibroplasia
Definition
TGF-B
Term
keratinocyte growth factor: stimulates keratinocyte migration, proliferation and differentiaion
Definition
KGF
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