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Gross Anatomy
Autonomic Nervous System
27
Medical
Professional
10/14/2008

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Term
Major subdivisions of ANS
Definition
1. parasympathetic (CNS and PNS)
2. sympathetic (CNS and PNS)
3. enteric (confined to walls of digestive tract)
Term
Types of Visceral Sensory Receptors
Definition
1. nociceptors
2. physiologic receptors
Term
Characteristics of nociceptors
Definition
1. respond to stimuli in damaged tissue or potential to be damaged
2. visceral pain--dull and difficult to localize
3. may include referred pain--crossing of ANS and somatic sensory nerves
4. carried by afferent nerve fibers of sympathetic ANS
Term
Characteristics of Physiologic Receptors
Definition
1. respond to innocuous stimuli
2. monitor visceral functions and elicit visceral reflexes for homeostasis
3. carried by afferent nerve fibers of parasympathetic portion of ANS
Term
Examples of physiologic receptors
Definition
1. chemoreceptors (carotid and aortic bodies)
2. mechanoreceptors (stretch, tension--Lower esophageal sphincter)
3. baroreceptors (arterial blood pressure)
Term
Target cells of efferent nerve fibers of ANS
Definition
1. vascular smooth muscle
2. non-vascular smooth muscle
3. cardiac muscle cells
4. secretory epithelial cels (mucous cells)
5. gastrointestinal endocrine cells (cholecystokinin-secreting cells)
Term
Enteric Nervous System
Definition
1. walls of gut from esophagus to anal canal
2. myenteric (Auerbach) and submucosal (Meissner's) plexus (all kinds of neurons and glia)
3. also to gallbladder, cystic duct, bile duct, pancreas
4. 100 million neurons
5. control over digestion
6. extensive communication with CNS--parasympathetic and sympathetic portions of ANS provide link
Term
Parasympathetic and Sympathetic ANS
Definition
1. wide distribution, interacts wit major viscera
2. parasympathetic--anabolic processes, restoration, and conservation of energy
3. sympathetic--deal with stressful situations
4. basal rates contribute to "tones"
Term
Dual Innervation of organ
Definition
1. most organs innervated by both parasymp and symp.
2. normal activity reflects parasymp and symp tones until it needs t be changed
Term
Single Innervation of Organ
Definition
1. only one nervous system regulates activity
2. blood vasculature (arterioles) to skin and skeletal muscles
Term
Selective Activation of Target Organs
Definition
1. activation of 1 organ is done independently of other organs innervated by the same system
Term
Somatic Distribution of Para and Sympath NS
Definition
1. body wall and extremities--> skeletal muscle, bone, and skin
2. sympathetic to smooth muscle of vasculature, secretory glands, arrector pili
3. NO parasympathetic distribution
Term
Visceral Distribution of Para and Sympa
Definition
1. viscera of thoracic, abdominal cavities, perineum, and pelvic cavity receive both symp and para
Term
Head Innervation by Para and Sympa
Definition
1. eyes and salivary glands receive both
2. vasculature, sweat glands, and arrector pili receive sympathetic like other somatic structures
Term
Sensory neurons of Para and Sympa
Definition
1. pseudounipolar with cell bodies in ganglia outside CNS
2. sensory of sympathetic: cell bodies in dorsal root ganglia in some spinal nerves (no cranial nerves have sympa)
3. sensory of para: cell bodies are in ganglia of spinal nerves and ganglia of cranial nerves
4. In PNS, follow same course as visceral efferent nerve fibers
Term
Motor Neurons of Para and Sympa
Definition
1. 2 neuron chain--preganglionic neuron with cell body in CNS (myelinated), postganglionic neuron with cell body in PNS ganglion (unmyelinated)
2. amplification of efferent single (1:2 to 1:20 preganglionic: postganglionic)
3. postganglionic of para=acetylcholine and vasoactive intestinal peptide
4. postganglionic of sympa=norepinephrine and neuroteptide Y
Term
Location of Preganglionic Nerve Cell Bodies in Parasympathetic System
Definition
1. craniosacral portion of ANS
2. brainstem nuclei of CN 3, 7, 9, 10
3. S2-S4 of spinal cord
4. most preganglionic derived from vagus nerve
Term
Location of Postganglionic Nerve Cell Bodies in Parasympathetic System
Definition
1. small and located within or adjacent to walls of organ being innervated
2. some functionally integrated into enteric NS
3. preganglionic are long in comparison to postganglionic
Term
Location of Sympathetic Preganglionic Nerve Cell Bodies
Definition
1. thoracolumbar portion
2. T1-L3 spinal cord DRG
Term
Location of Sympathetic Postganglionic Nerve Cell Bodies
Definition
1. preganglionic are short compared to postganglionic
2. sympathetic trunks (paravertebral): parallel to vertebral column from neck to sacrum (-25 pearls on a string)
3. prevertebral: limited to abdominal cavity, anterior to vertebral column, and adjacent to major branches of abdominal aorta (i.e. celiac ganglion)
Term
Sympathetic Innervation of somatic structures: postganglionic (except head)
Definition
1. preganglionic leave as anterior roots of T1-L3 spinal nerves
2 enter sympathetic trunks (white rami communicates)
3. postganlionic acons send axons back to T1-L3 spinal nerves and distribute to body (gray rami communicantes)
Term
Somatic innervation of head
Definition
1. preganglionic axons from head enter synapse on most superior part of sympathetic trunk (superior cervical ganglia)
2. postganglionic axons jump onto carotid arteries and distribute via periarterial nerve plexus
Term
Sympathetic innervation of head
Definition
same as somatic innervation to head
Term
sympathetic innervation of thoracic viscera
Definition
1. preganglionic axons from T1-T5 spinal cord
2. postganglionic axons exit cervical and upper thoracic ganglia of symp. trunks
3. project to cardiac and pulmonary nerve plexuses
4. Join with preganglionic axons of vagus nerve and follow periarterial nerve plexus to heart and lungs
Term
Sympathetic innervation of abdominal and pelvic viscera
Definition
1. preganglionic axons from T5-L3 enter sympathetic trunks but do not synapse
2. These splanchnic nerves course to prevertebral ganglia
3. postganglionic course to target organs via periarterial nerve plexus
Term
Influences of ANS from Higher Brain Centers
Definition
1. Input from reticular formation, hypothalamus, thalamus, limbic lobe, prefrontal cortex
2. accounts for effects of exterior sensory cues, emotional status, and cerebral function on ANS activity
Term
Influences of ANS from Higher Brain Centers
Definition
1. Input from reticular formation, hypothalamus, thalamus, limbic lobe, prefrontal cortex
2. accounts for effects of exterior sensory cues, emotional status, and cerebral function on ANS activity
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