Term
| Staphylococci - main pattern of dz |
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Definition
localised lesions
-pyogenic skin infections
e.g. dermatitis, pyoderma, abscesses, impetigo (superficial/mild, furunculosis (deep/severe), botryomycosis
-systemic infections
septiceamia +/- deposition / localised damage |
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Term
|
Definition
-animal and human skin / MM commensals (upper resp and upper GIT)
-also in environment worldwide |
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Term
| Staphylcoccus hyicus - normal habitat |
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Definition
-pig skin commensal esp
-also cattle udder skin / milk
-poultry skin / nares |
|
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Term
| Staphylcoccus hyicus - dz |
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Definition
-Greasy pig dz
-bovine mastitis
-dermatitis in goats, cattle horses |
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Term
| Staphylcoccus hyicus - greasy pig dz |
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Definition
-exudative epidermitis in piglets 1-12weeks
-due to epidermolyic toxin
-may be acute or chronic
-inf. skin will slough so inf. animals should be separated |
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Term
| Staphylcoccus hyicus - greasy pig dz sequence of events |
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Definition
facial wounds allow entry --> inflam.
-->wrinkled skin and polyarthritis (chronic)
-->scaly / peeling skin --> systemic inf. and poss death (acute) |
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Term
| Staphylococcus pseudointermedius - normal habitat |
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Definition
| -dog and cat skin / nasopharynx commensal |
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Term
| Staphylococcus pseudointermedius - dz |
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Definition
-bovine mastitis
-dog and skin skin infections
-canine variety of infections
e.g. otitis externa, ocular inf., urinary tratc inf., pyometra, joint inf |
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Term
| Staphlococcus aureus - main dz |
|
Definition
-synovitis in poultry (bumble foot)
-tick (lamb) pyaemia
-mastitis
-botryomycosis |
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Term
| Staphlococcus aureus - synovitis in poultry |
|
Definition
-pyogranulomatous inf. lesion in joints
-acute mild - bumblefoot - cuts in feet where bact gain entry, results in swelling and inflam - bird can't walk well
-acute severe - artritis wing and leg joints) +/- septicaemia and poss. death
-chronic - osteoarthritis |
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Term
| Staphlococcus aureus - tick (lamb) pyaemia - cause |
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Definition
-tick bite allow bact. entry
i.e. NOT tick-borne
-seasonal dz - spring when ticks active |
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Term
| Staphlococcus aureus - tick (lamb) pyaemia - disease |
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Definition
Acute - abscesses +/-septicaemia
Chronic - deposition in vital organs/joints - can be severly crippled (growing quickly!) |
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Term
| Staph. aureus masitis - spp |
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Definition
-in most spp
-most common cause of mastitis in lactating ewe |
|
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Term
| Staph. aureus bovine masitis - disease |
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Definition
Acute gangrenous form - alpha-haemolysin damages bv. and causes necrosis
-inf. quarter becomes hard, blue and gangrenous
-toxaemia, w. high fever, death as toxins spill into blood
-chronic subclinical form is most common - economically significant due to decr. milk yield, high WBC count and potential passage to humans |
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Term
| Staph aureus Botryomycosis - disease |
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Definition
-chronic infection of accidental / surgical wounds in many spp
-in pigs often udder
-most common in colts post-casration |
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Term
| Staph aureus Botryomycosis - colts |
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Definition
-commensals on skin enter spermatic cord stump
-mass of abscesses form
-host walls off abscesses w. tough fibrous capsule
-if organism spreads systemically then rapidly fatal |
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Term
| Staph aureus - alpha-haemolysin toxin |
|
Definition
-a plama membrane porin i.e. cytocidal - highly potent
-affects WBC - lysosome disruption
-smooth muscle in bv walls - constriction / necrosis
-many cell types - necrosis / dermonecrosis |
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Term
| Staph aureus - alpha-haemolysin lab test |
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Definition
-complete RBC lysis (narrow clear zone)
-neutralisation assay |
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Term
| Staph aureus - beta-haemolysin toxin |
|
Definition
partial RBC lysis - wide zone
-hot-cold haemolysis |
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Term
|
Definition
-R genes are common and widespread so bare w. antibiotics - check sensitivity
-Pus is protective - need quite hig levels of ABs
-lamb pyaemia - tick control |
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Term
| Staph aureus - prevention |
|
Definition
staphs are R to drying, phenolic compounds, 60C for 30mins, 20%NaCl
-sensitive to common disinfectants, aniline dyes
-vacc are available - staph hyicus for sows, staph aureus mastitis but acute only (whihc is less common) |
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