Shared Flashcard Set

Details

Gram Negative Bacteria
Microbiology Quiz 2
97
Science
Post-Graduate
11/04/2011

Additional Science Flashcards

 


 

Cards

Term
Escherichia Coli is most common cause of
(4 things)
Definition
1.Urinary tract infection
2. Gram negative rod sepsis
3. Neonatal meningitis and
4. Travelers diarrhea.
Term
Transmission of E Coli
Definition
Normal habitat is gut of man and animals; may colonize the lower end of urethra and vagina.
Term
E Coli is spread by
Definition
contact and ingestion (fecal-oral route); may be food associated; may be endogenous.
Term
Treatment and prevention of E Coli
Definition
antibiotic
Term
Vacciine of E Coli
Definition
NONE
Term
E Coli 157 binds to
Definition
brush boarder of intestinal mucosa
Term
E Coli 157 produces
Definition
verotoxin that destroys microvilli
Term
Verotoxin of e coli 157 enters blood causing
Definition
vascular endothelial damage and increased platelet aggregation
Term
Which causes hemorrhagic colitis, or hemolytic uremic syndrome
Definition
E Coli 157
Term
Platelet fibrin thrombi form causing ischemic damage to
Definition
colon, kidney, and other tissues (E Coli 157)
Term
Salmonella species cause
Definition
enterocolitis, enteric fevers such as typhoid fever and sepsis.
Term
What is the most common causes of bacterial enterocolitis in USA.
Definition
Salmonella
Term
Transmission of Salmonella/typhoid fever
Definition
Habitat is the enteric tract of humans and animals, e.g.,Chicken and domestic livestock. Transmission is by the fecal-oral route.
Term
Treatment of salmonella/typhoid fever
Definition
Antibiotic is the drug of choice
Term
Prevention of salmonella
Definition
Public health measures, e.g., sewage disposal, chlorination of water supply, stool cultures for food handlers, and hand washing prior to food handling.
Term
Salmonella enteriditis ingestion is absorbed in the
Definition
epithelial cells in terminal portion of small intestine
Term
Bacteria from the small intestine penetrate cells in the
Definition
ilieocecal region, causing high grade fever (continuous)
Term
Patient complaints of salmonella
Definition
headache, lower abdominal pain-close to appendix, diarrhea
Term
Typhoid fever is closely related to
Definition
salmonella
Term
Bacteroids are
Definition
Obligatory anaerobic gram negative rods
Term
Members of the genus bacteroids are the predominant anaerobes found in
Definition
the human colon.
Term
Bacteroids are part of normal flora and only cause disease when they gain
Definition
access to the blood during bowel penetration for example during surgery or trauma.
Term
Bacteroids are however the most common cause of serious infections by
Definition
anaerobic organisms
Term
Treatment of bacteroids
Definition
metronidazole is the antibiotic of choice
Term
Prevention of bacteroids are
Definition
pre-operative antibiotic can be administered
Term
Vibrio Cholerae disease is
Definition
Cholera
Term
Transmission of Cholera
Definition
by the fecal oral route
Term
Treatment of Cholera
Definition
treatment consists of prompt replacement of water and electrocytes, either orally or intravenously
Term
What transmits diarrhea through cAMP
Definition
Cholera
Term
Prevention of cholera
Definition
public health measures to ensure clean water and good food hygiene
Term
The vaccine of cholera is composed of
Definition
killed organisms and has limited usefullness
Term
Shigella Disease: Shigella species cause
Definition
enterocolitis ( bloody dysentery).
Term
ShigellaTransmission :
Definition
By fecal-oral route.
Term
Shigella Treatment:
Definition
The main treatment of shigellosis is fluid and electrolyte replacement. In severe cases antibiotic is given.
Term
Prevention of shigella
Definition
Public health measures, e.g., sewage disposal, chlorination of the water supply, stool cultures for food handlers, and hand washing prior to food handling.
Term
Shigella patients will present with
Definition
bloody diarrhea, mucus, and abdominal cramping
Term
Campylobacter Jejuni disease
Definition
diarrhea
Term
Campylobacter Jejuni transmission
Definition
Animal reservoir. Organisms acquired from contaminated food and milk. Person to person spread is rare.
Term
Treatment of Campylobacter Jejuni
Definition
No specific treatment is required for diarrhea. Erythromycin is indicated for invasive disease
Term
Prevention of Campylobacter Jejuni
Definition
Prevention depends of good food hygiene. There are no vaccine available
Term
Campylobacter Jejuni causes
Definition
Inflammatory enteritis
Term
Helicobacter Pylori Disease is
Definition
Gastritis and duodenal ulcers, associated with gastric carcinoma.
Term
Helicobacter Pylori Transmission:
Definition
Person to person transmission (fecal-oral) likely.
Term
Helicobacter PyloriInfections occur in
Definition
multiple family members.
Term
Helicobacter Pylori treatment
Definition
Proton pump inhibitors plus antibiotics (e.g., metronidazole, tetracycline, clarythromycin)
Term
Helicobacter Pylori causes stomach acid to
Definition
neutralize
Term
Helicobacter Pylori causes the stomach mucus
Definition
to be destroyed exposing the underlying connective tissue
Term
Klebsiella Pneumonia causes
Definition
necrotizing lobar pneumonia in individuals compromised by alcoholism, diabetes or chronic obstructive pulmonary disease (COPD), emphysema
Term
Klebsiella cause of a hospitalized patient is
Definition
UTI and bacteremia
Term
Klebsiella Pneumonia is also called
Definition
lobar pneumonia because it affects an entire lobe instead of a small area.
Term
Klebsiella fatality rate
Definition
high
Term
Pseudomonas aeruginosa
Definition
large bacteria, opportunistic bacteria (only patients that are healthy may survive the bacteria)
Term
Pseudomonas aeruginosa Most often in compromised patients with
Definition
- natural immunological deficiency
- immunosuppressive therapy
- burns
- chronic pulmonary disease (cystic fibrosis)
- IV narcotic users
- renal dialysis
Term
Pseudomonas aeruginosa Infections take form of
Definition
septicemia, abscesses, corneal infections, meningitis, bronchopneumonia, and subacute bacterial endocarditis, otitis externa (children), UTI (not normal UTI infection)
Term
Pseudomonas aeruginosa Treatment often fails with
Definition
> 80% mortality
Term
Pseudomonas aeruginosa also common in patients with
Definition
cystic fibrosis
Term
Patients present with
Definition
UTI, bluish greenish pus
Term
Hemophilus Influenza disease
Definition
It causes pneumonia in adults particularly in those with chronic obstructive lung disease
Term
Hemophilus Influenza It is still an important cause of
Definition
upper respiratory tract infections,( otitis media, sinusitis, and epiglotitis) and sepsis in children, broncho-pneumonia
Term
Hemophilus Influenza used to be a big cause of death in young people under 5 because of
Definition
Prevention--Vaccine
Term
Treatment Hemophilus Influenza
Definition
—Antibiotic (Ceftriaxone)
Term
Hemophilus Influenza most common in patients with
Definition
COPD
Term
Hemophilus Influenza is a contiguous spread from
Definition
site of colonization in the respiratory tract
Term
Disseminated spread of Hemophilus Influenza is via
Definition
the blood stream
Term
Legionella disease is
Definition
Pneumonia, both in the community and hospitalized immunocompromized patients
Term
Legionella is one of the causes of
Definition
atypical pneumonia.
Term
Transmission of Legionella
Definition
Environmental saprophyte (any organism living upon dead or decaying organic matter) acquired by inhalation of contaminated water from shower, air conditioning systems, and cooling towers.
Term
Treatment of Legionella
Definition
Erythromycin
Term
Prevention of Legionella
Definition
No vaccine available. Prevention depends upon maintenance of hot water and air conditioning systems in large buildings such as hospitals, offices and hotels.
Term
Bordetella Pertussis Disease
Definition
– Whooping Cough
Term
Bordetella Pertussis Transmission
Definition
—Human pathogen spread by airborne route from cases of disease.
Term
Bordetella Pertussis Treatment and Prevention–
Definition
Erythromycin (antibiotic) is the drug of choice for cases and close contacts of whooping cough.
Term
Bordetella Pertussis Vaccine is
Definition
used as a part of the immunization program so disease is not as fatal as it used to be.
Term
Pasteurella Multocida Disease
Definition
Caused by infected animal bite (e.g. cat or dog).
Term
Pasteurella Multocida Acute onset
Definition
of redness, pain and swelling.
Term
Pasteurella Multocida Transmission—
Definition
Zoonotic (animal bite) infection.
Term
Treatment and prevention Pasteurella Multocida
Definition
Treat animal bite as polymicrobial infection (multiple antibiotics).
Term
The bubonic plague
Definition
The term 'bubonic' refers to the characteristic bubo or enlarged lymphatic gland.
Term
Yersinia Pestis disease
Definition
Plague
Term
Transmission of Yersinia Pestis
Definition
Zoonotic infection transmitted to humans through the bite of fleas carried by rodents.
Term
Treatment and Prevention of Yersinia Pestis
Definition
Streptomycin is the drug of choice with tetracycline as an alternative
Term
Yersinia Pestis vaccine
Definition
Vaccine available for those at risk.
Term
Yersinia Pestis control
Definition
Control and eradication of infected animals is important.
Term
Bubonic plague entry to exit
Definition
entry, spread to lymphatics, disease infection buboes (black hemorrhagic lymph nodes, pneumonia, internal organ hemorrhage), exit (highly contagious)
Term
Pneumonia Plague entry to exit
Definition
entry (sinus), disease (pneumonia, 100 % fatal), exit (highly contagous)
Term
Bacteria plague spread by blood
Definition
baceterial growth in lungs, plague meningitis
Term
Plague spread human to human is called
Definition
pneumonic plague
Term
Brucella Disease—
Definition
Brucella species cause brucellosis (undulant fever)
Term
Brucella Transmission—
Definition
Zoonotic infections transmitted to man through consumption of contaminated milk or other unpasteurized dairy products and by direct contact (veterinarians and farmers).
Term
Brucella Treatment and Prevention—
Definition
Doxycycline alone or in combination (e.g., streptomycin).
Term
Brucella Prevention depends upon
Definition
eliminating the disease from domestic animals by vaccination and pasteurization of milk.
Term
Brucella not usually spread to
Definition
person to person, only animal to person
Term
Francisella Tularensis Disease–
Definition
Tularemia (glandular fever)
Term
Transmission of Francisella Tularensis is
Definition
Zoonotic infections transmitted to humans through contact with infected animals, the bite of infected fleas or ingestion of contaminated meat.
Term
Francisella Tularensis Treatment and Prevention—
Definition
Streptomycin or Gentamycin.
Term
Francisella Tularensis Prevention—
Definition
Live attenuated vaccine is available for at risk individual (hunters, and laboratory workers).
Term
Tularemia also called
Definition
rabbit fever or glandular fever
Supporting users have an ad free experience!