Shared Flashcard Set

Details

GMPS
Transplants
10
Other
Graduate
02/10/2015

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Cards

Term
hyperacute rejection
Definition
ischemia and necrosis up to 48 hrs. after transplant
generally unresponsive to tx
must remove
Term
acute rejection
Definition
3 months-1 yr
changes in immunosuppression
early intervention is key here an can be reversed
body is attacking the graft or oran
T-lymphocytes react to graft antigens, anti-rejection meds can stop attack
Term
chronic rejection
Definition
first few months with a progressive breakdown
B-cells and T-cell response
chronic inflammation deteriorates function
meds may slow down, but graft failure is common and needs re-implant
Term
renal/kidney
Definition
most common transplant
Term
kidney
Definition
can last 72 hours before being harvested with cadavers
living transplants preferred but less common
Term
orthotopic
Definition
recipients heart is removed and a new heart is placed in same anatomical position
Term
heterotopic
Definition
"piggy-back" the diseased heart is retained
these are rare but used for patients with pulmonary hypertension
Term
pancreas
Definition
increased rate of rejection
Term
pancreas tranplant
Definition
not life saving surgery, stabilizing transplant to
Term
lung transplant
Definition
contraindicated with heart/coronary heart disease
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