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Glyoxylate Cycle
Steps and components of the Glyoxylate Cycle
5
Biochemistry
Undergraduate 4
03/20/2017
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Term
Step 1 (glyoxylate)
 Definition
  • acetyl CoA to citrate by citrate synthase
Term
Step 2 (glyoxylate)
 Definition
citrate to isocitrate by aconitase
Term
Step 3 (glyoxylate)
 Definition
  • isocitrate to succinate and glyoxylate via isocitrate lyase
  • first reaction in cycle different from Kreb's cycle
  • isocitrate lyase is a novel enzyme for this reaction
Term
Step 4 (glyoxylate)
 Definition
  • glyoxylate to malate via malate synthase
  • malate synthase is novel enzyme for this cycle
Term
Step 5 (glyoxylate)
 Definition
  • Malate to oxaloacetate via malate dehydrogenase
  • formation of NADH
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