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all cells, continuous and constant transport of glucose into cell insulin indep |
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liver + pancreas only open when glucose high insulin indep |
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muscle and fat - more GLUT4 receptors when insulin / exercise high insulin DEP, GLUT4 trapped in vessicles |
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fructose transporter in small intestine |
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allosteric= effectors/inhibitors bind allosterically |
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bis = 2 P not bound together |
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2 pyruvate 2 ATP 2NADH 2H+ 2H2O |
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pyruvate-->Co2 + acetaldehyde--> ethanol NADH-->NAD+ |
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nad binding domain structure |
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in dehydrogenases 4a helices+ 6 b parallel sheets = ROSSMAN FOLD |
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what is converted to glycolytic intermeds |
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galactose fructose to g and f 6 p |
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inhibited by high ATP allosterically AMP reverses inhibition inhibited by low pH |
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2ADP-->ATP + AMP therefore high AMP indicates energy need |
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between f6p and f1,6bp rapidly increase flux through pathway but consume ATP |
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