Term
| Where in the cell does glycolysis take place? |
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Definition
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Term
| What are the starting and ending chemicals of glycolysis |
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Definition
Glucose --> pyruvate and/or lactate
Overall aerobic: Glucose + 2pi + 2(NAD+) + 2 ADP >>>> 2 pyruvate + 2 ATP + 2 NADH +2H + 2H2O
Overall anaerobic: Glu + 2pi + 2ADP>>> 2 Lactate + 2ATP + 2H2O |
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Term
| What must every cell that metabolizes glucose do first? What enzymes do this? |
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Definition
| Phosphorylate glucose to Glucose-6-phosphate. Catalyzed by either hexokinase or glucokinase. |
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Term
| In glycolysis, what is the enzyme, substrate, and product for the committed step? Is ATP generated or used in this reaction? |
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Definition
| Committed step is phosphorylation of F6P to F1,6B by phosphofructokinase-1. ATP is used in this step. |
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Term
| What are some control factors affecting glycolysis? |
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Definition
1. PFK-1 inhibition by citrate, high levels of ATP. AMP, cAMP, ADP, and Pi are activators.
2. (Liver) F16BPase flow chart is necessary to adequately answer this question. |
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Term
| In what steps is ATP generated? |
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Definition
1. Conversion of 1,3-BPG to 3PG by phosphoglycerate kinase.. 1 ATP is produced.
2. Second ATP is produced in the conversion of PEP into pyruvate by pyruvate kinase. 4 ATP, but net of 2 |
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