Term
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Definition
| Glucose + 2NAD+ + 2ADP + 2Pi ---> 2 NADH + 2 ATP + 2H+ + 2 Pyruvate |
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Term
| Pyruvate Conversion to AcetylCoA Net Rx (w. enzyme) |
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Definition
Pyruvate + NAD+ + CoA ---> AcetylCoA + NADH +CO2
Enzyme needed: Pyruvate Dehydrogenase Complex |
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Term
| TCA Cycle: Acetyl CoA ---> Citrate |
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Definition
Oxaloacetate + AcetylCoA + H2O ---> Citrate + CoA + H+
Enzyme needed: Citrate synthase |
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Term
| TCA Cycle: Citrate ---> Isocitrate |
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Definition
Citrate ---> Isocitrate
Enzyme needed: Aconitase |
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Term
| TCA Cycle: Isocitrate ---> α-ketoglutarate |
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Definition
Isocitrate + NAD+ ---> NADH + CO2+α-ketogluturate
Needed Enzyme: Isocitrate dehydrogrenase |
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Term
| TCA Cycle: α-ketogluturate ---> succinylCoA |
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Definition
α-ketogluturate + NAD+ ---> succinylCoA + NADH + CO2
Enzyme need: α-ketogluturate dehydrogenase |
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Term
| TCA Cycle: Succinyl CoA ---> Succinate |
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Definition
Succinyl CoA --> Succinate generates ATP from ADP (indirect in animals: GDP converted to GTP first)
Needed enzyme: succinylCoA synthetase |
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Term
| TCA Cycle: Succinate --> Fumarate |
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Definition
Succinate + FAD ---> Fumarate + FADH2
Enzyme needed: succinate dehydrogenase |
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Term
| TCA Cycle: Fumarate --> Malate |
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Definition
Fumarate + H2O --> Malate
Enzyme needed: Fumarate hydratase |
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