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Definition
| The relaxed (active) form of phosporylase |
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Term
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Definition
| the tense (inactive) form of phosphorylase |
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Definition
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Definition
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Definition
| fructose-1,6-bisphosphate |
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Term
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Definition
| the same as the cAMP dependent protein kinase |
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Definition
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Definition
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Term
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Definition
| an alpha linkage between two sugars, one at carbon 1, the other at carbon 4 |
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Term
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Definition
| an alpha linkage between two sugars, one at carbon 1, the other at carbon 6 |
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Definition
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Term
| The largest glycogen stores are in the? |
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Definition
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Term
What removes glucosyl units one at a time from the ends of the glycogen chains,converting them to
glucose 1-phosphate without resynthesizing UDP-glucose or UTP? |
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Definition
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Term
| What removes the glucosyl residues near each branch point? |
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Definition
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Term
| Glucagon activates which two pathways? |
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Definition
| Gluconeogenesis and Glycolysis |
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Term
| G6P is converted to G1P by? |
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Definition
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Term
| What is the enzyme that attaches the glucosyl residues in 1,4-bonds? |
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Definition
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Term
When the chain reaches approximately 11 residues in length, a 6- to 8-residue piece is cleaved by ___________ and reattached toa glucosyl unit by an
alpha-1,6-bond. |
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Definition
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Term
| What is the protein to which glycogen is attached, glycosylates itself (autoglycosylation) by attaching the glucosyl residue of UDP-glucose to the hydroxyl side chain of a serine residue in the protein? |
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Definition
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Term
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Definition
| genetic deficiency in muscle glycogen phosphorylase (inconvenience) |
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Term
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Definition
| genetic deficiency in liver glycogen phosphorylase (lethal) |
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Term
| What can hydrolyze glycogen in a lysosome? |
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Definition
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Term
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Definition
| genetic defect of lysosomal glucosidase (children with this normally die of heart disease) |
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Term
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Definition
| a cAMP directed phosphorylation cascade |
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Term
| What happens to glycogen phosphorylase when glucagon is present? |
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Definition
| It is phosphorylated(by Protein Kinase A plus 9 more) and goes from the b(inactive) to a(active) form. |
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Term
| What happens to glycogen synthase when glucagon is present? |
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Definition
| It is phosphorylated(by Protein Kinase A), it goes from the a(active form to the D or b(inactive) form |
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Term
| What class of proteins remove the phosphate groups,bound to serine or other residues of enzymes,by hydrolysis? |
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Definition
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Term
| What protein is one of the major protein phosphatases involved in glycogen metabolism, removes phosphate groups from phosphorylase kinase, glycogen phosphorylase, and glycogen synthase? |
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Definition
| Hepatic Protein Phosphatase-1 (HPP-I) |
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Term
| What is as an allosteric effector, inhibits liver glycogen phosphorylase a by stimulating dephosphorylation of this enzyme? |
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Definition
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Term
| Epinephrine has two receptors which are? |
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Definition
| alpha and beta agonist receptors |
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Term
| What epinephrine receptor transmits a signal through G proteins to adenylate cyclase increasing cAMP, thus activating protein kinase A. (This part of epinephrine is similar to glucagon)? |
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Definition
| epinephrine binding to beta-agonist receptor |
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Term
| Epinephrine binding at this receptor in the hepatocyte activates glycogenolysis and inhibits glycolysis by increasing levels of Ca2+? |
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Definition
| epinephrine binding to alpha-receptors |
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