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GI: IBD
GI: IBD
12
Anatomy
Graduate
01/29/2012

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Term
Conditions associated with IBD:
Definition
- Oral ulcers
- Polyarticular peripheral arthritis
- Spondylitis
- Sacrilitis
- Episcleritis- uveitis
- Erythema nodosum
- Pyoderma gangrenosum
- Hepatitis
- Sclerosing Cholangitis
- Thromboemoblic events

(all autoimmune inflammatory reactions)
Term
Lab findings of IBD:
Definition
- Anemia (Fe deficiency)
- Hypoalbuminemia
- Leukocytosis
- Thrombocytosis
- Fecal leukocytes
- P-ANCA +
Term
Ulcerative Colitis treatment:
Definition
SPICS
- Sulfasalazine (mainstay)
- Prednisone
- Infliximab
- Cyclosporine
- Surgery (only 25% of pts with UC get surgery)
Term
Crohn's treatment:
Definition
SCAMIS
- Sulfasalazine
- Ciprofloxacin
- Azathiopurine
- Metronidazole
- Infliximab
- Surgery (75% of pts with Crohn's get surgery)
Term
Pts with IBD are at increased risk for what type of renal calculi and why?
Definition
oxalate renal calculi b/c impaired absorption of fatty acids
Term
IBD increases risk for what 3 types of cancers:
Definition
- Colorectal cancer
- Adenocarcinoma of the small bowel
- Lymphoma
Term
Risk factors for cancer with IBD:
Definition
- Long duration of IBD (> 8-10 years)
- Early age at onset
- Severity of inflammation
- Family history of colorectal cancer
- Concomittant PSC
- Premalignant dysplasia of epithelium- low grade dysplasia on flat mucosa= HIGH RISK
Term
IBD cancer screening:
Definition
- Colonoscopy 8 years after dx, repeat every 1-2 years
- Random 4 quandrant biopsies every 10 cm throughout colon
- Colectomy for low grade dysplasia
Term
IBS diarrhea tmt:
Definition
- Loperamide
- Cholestyramine
- Alosetron
Term
IBS constipation tmt:
Definition
- Psyillium husk
- Methyl cellulose
- Clacium polycarbophil
- Lactulose syrup
- Polyethylene gycol
- Lubipristone
- Magnesium hydroxide
Term
IBS tmt for abdominal pain:
Definition
- Bentyl (smooth muscle relaxant)
- TCA: Elavil
- SSRI: Celexa
Term
chronic anal fissure tmt:
Definition
- topical nitroglycerin or diltiazem
- injected botulinum toxin into internal anal sphincter
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