Term
|
Definition
- abnormally frequent discharge of semisolid or fluid fecal matter from the bowel
- > 200 g/day - > 15 g/kg under 2 y/o |
|
|
Term
Medications that may cause diarrhea: |
|
Definition
- Metformin - Exenatide - Theophylline - Colchicine - PPI's - HAART - Antibiotics- erythromycin - Promotility agents - Laxatives |
|
|
Term
|
Definition
- loose watery stools - NO blood, mucus, or WBCs |
|
|
Term
|
Definition
Metronidazole 250 mg tid x 5 days |
|
|
Term
Parasitic cause of diarrhea that is self limiting in most pple, but lifethreatening in AIDs. Tend to have > 17 liters/diarrhea. This parasite has an outer coat so its resistant to chlorine. Leading cause of recreatiional water associated gastroenteritis: |
|
Definition
|
|
Term
This type of E.coli adheres to the small bowel and releases 2 enterotoxins: |
|
Definition
Enterotoxigenic E. coli > Traveler's diarrhea |
|
|
Term
Difference b/w diarrhea with Enterohemorrhagic E. coli and Enterotoxigenic E. coli: |
|
Definition
- Enterohemorrhagic: bloody diarrhea - Enterotoxigenic: no blood, mucus, or WBC |
|
|
Term
Enteroinvasive bacteria that mimic Shigella by causing local colonic inflammatory response: |
|
Definition
- Enterotoxigenic E. coli |
|
|
Term
Onset of symptoms and duration of symptoms with Salmonella: |
|
Definition
- onset: 8-48 hours after exposure - duration: 1-2 weeks |
|
|
Term
What type of diarrhea occurs with salmonella? |
|
Definition
|
|
Term
Salmonella Typhi symptoms: |
|
Definition
- Headache - Cough - Sore throat - Malaise - Anorexia - Diaphoresis - Abdominal pain - Constipation - Pea soup diarrhea |
|
|
Term
Shigella diarrhea and other shigella symptoms? |
|
Definition
- watery diarrhea - tenesmus - fever - stomach cramps |
|
|
Term
Shigella causes watery diarrhea, but there may also be __ or __ in the stools. |
|
Definition
|
|
Term
complications of shigella: |
|
Definition
- febrile seizures - encephalopathy - Reiter syndrome |
|
|
Term
With shigella __ should be avoided, but ___ should be used. |
|
Definition
- antidiarrheals should be avoided - antibiotics should be used |
|
|
Term
Antibiotis to treat Shigella: |
|
Definition
- Ceftriazone 250 mg IM - Ciprofloxacin 250 mg bid x 5 days - SMZ/TMP bid x 5 days - Azithromycin 500 mg for first day, 250 mg for 4 more days |
|
|
Term
|
Definition
- loose, watery, or bloody stools |
|
|
Term
Campylobacter is self-limiting but has a shorter course with antibiotics, what antibiotics would you use? |
|
Definition
- Erythromycin 250-500 mg/day for 5-7 days - Ciprofloxacin 500 mg BID x 3 days |
|
|
Term
Complications of Campylobacter jejuni? |
|
Definition
- Hemolytic Uremic Syndrome (HUS) - Guillain Barre (40%) |
|
|
Term
2 bacterial causes of diarrhea that may cause HUS: |
|
Definition
- Enterohemorrhagic E. coli - Campylobacter jejuni |
|
|
Term
Bacterial diarrhea from undercooked pork products: |
|
Definition
- Yersinia enterocolitica |
|
|
Term
bacterial diarrhea that makes you unable to chelate iron? |
|
Definition
|
|
Term
bacterial diarrhea that causes pseudoappendicitis? |
|
Definition
|
|
Term
Complications of Yersinia enterocolitica: |
|
Definition
- Erythema nodosum - Reiter syndrome |
|
|
Term
Two causes of bacterial diarrhea that can result in Reiter Syndrome: |
|
Definition
- Shigella - Yersinia enterocolitica |
|
|
Term
Tmt for Yersinia enterocolitica: |
|
Definition
- Levofloxacin - Ciprofloxacin - SMZ/TMP - Ceftriaxone |
|
|
Term
Causes of Clostridium difficile: |
|
Definition
- Cephalosporins - Clindamycin - Ampicllin - Amoxicillin - Chemo |
|
|
Term
Complications of C. diff: |
|
Definition
- Pseudomembranous colitis: 2-10 mm plaques, up to 25% of pts with mild disease - Toxic megacolon |
|
|
Term
|
Definition
- Vancomycin 125 mg QD for 10-14 days - Metronidazole 250 mg QD for 10-14 days - Bacteriotherapy- stool transfer from someone else |
|
|
Term
Vibrio parahaemolyticus is found in __ __ and is associated with __ __. |
|
Definition
- brackish saltwater - undercooked shellfish |
|
|
Term
Vibrio parahaemolyticus symptoms: |
|
Definition
- watery diarrhea - abomdinal cramping - nausea - vomiting - fever - chills |
|
|
Term
|
Definition
- watery rice water stools - vomiting - leg cramps |
|
|
Term
Where does Vibrio cholera occur: |
|
Definition
- Indian subcontinents - sub-Sarahan Africa - coastal TX and LA |
|
|
Term
focus of tmt with Vibrio cholera: |
|
Definition
- rehydration more important than antibiotics |
|
|
Term
What type of bacterial diarrhea will antibiotics not work against and why? |
|
Definition
Staphylococcus aureus b/c the abx won't kill the toxin and thats what makes you sick |
|
|
Term
|
Definition
|
|
Term
|
Definition
- undercooked meats, poultry, or legumes - diarrhea and cramps - treat with rehydration |
|
|
Term
Screen and dx for Celiac Disease: |
|
Definition
Screen with autoantibodies: - Anti-tissue transglutaminase (tTGA) - IgA Anti-gliadin antibodies - IgA Anti-endomysial antibodies
Diagnsosis - Fecal fat Sudan stain - GOLD STANDARD: SMALL BOWEL BIOPSY |
|
|
Term
Foods pts with Celiac can eat: |
|
Definition
CRAP and more
- Corn - Rice - Arrowroot - Potatoes - Soy - Buckwheat - Quinoa - Flax - Tapioca |
|
|
Term
Symptoms of Whipple's Syndrome: |
|
Definition
- Arthralgias - Weight loss - Diarrhea - Abdominal pain - Cough - Lymphadenopathy - Fever
results in MALABSORPTION fatal if untreated |
|
|
Term
Examples of conditoin that can lead to bacterial overgrowth and thus malabsorption: |
|
Definition
- Gastric achlorhydria- due to gastric surgery or chronic PPI use - Radiation enteritis - Motility disordres - Fistulas - Elderly |
|
|
Term
one of the most common complications of having gall bladder removed: |
|
Definition
diarrhea after surgery, can be acute or chronic
treat with cholestyramine |
|
|
Term
Chronic diseases tha may cause diarrhea: |
|
Definition
- IBD - Microscopic colitis - Radiation colitis |
|
|
Term
Microscopic colitis treatment: |
|
Definition
- Loperamide or Diphoxylate/atropine - Bismuth subsalicylate - 5 ASA/Sulfasalzine - Budesonide or Prednisone |
|
|
Term
Examples of diseases that cause motility disorders of the gut: |
|
Definition
- IBS - DM - Scleroderma - Hyperthyroidism - Addison's |
|
|
Term
|
Definition
Antispasmodics: - Hyoscamine - Dicyclomine |
|
|
Term
Sign of colonoscopy of laxative abuse: |
|
Definition
|
|
Term
Diverticulosis coli usually affects the __ colon. |
|
Definition
|
|