Term
| Risk Factors for colorectal cancer: |
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Definition
- Hereditary Polyposis Syndrome
- Hereditary nonpolyposis colon cancer (HNPCC)
- Family history of "cancer family syndrome"
- First degree relatives with colorectal carcinoma
- History of previous colorectal carcinoma
- Previous endometrial or ovarian cancer, especially when diagnosed at an early age
- Women undergoing radiation for gynecologic cancer
- IBD (UC or Crohn's)
- Diet high in fat, meat, and beer
- Age > 40 |
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Term
| Abdominal distention and tenderness with colorectal cancer are indicative of: |
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Definition
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Term
| Labs to order if you suspect colorectal cancer: |
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Definition
- Fecal Occult Blood Test (FOBT)
- CBC to look for iron deficient anemia
- Plasma Carcinoembryonic Antigen (CEA) level
- Liver Function Tests (LFT) |
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Term
| What imaging study helps assist in preoperative staging of Colorectal Cancer: |
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Definition
| - CT scanning of the abdomen, pelvis, and chest |
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Term
| What imaging study is good for look at CRC and its mets? |
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Definition
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Term
| Recommendations for colorectal cancer screening in average risk person: |
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Definition
Beginning at age 50:
- Colonscopy every 10 years
- Computed Tomographic Colonography, or Flexible Sigmoidoscopy, or Double Contrast Barium Enema everey 5 years
- Stool blood testing annually or stool DNA testing acceptable but not preferred |
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Term
| Recommendations for colorectal screening in those with one or two first degree relatives with CRC at any age or adenoma less than 60 y/o: |
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Definition
| - colonscopy every 5 years starting at age 40, or 10 years younger than earliest dx, whichever comes first |
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Term
| Recommendations for CRC screening in those with a hx of CRC: |
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Definition
| - colonscopy every 3-5 years after removal of all index polyps |
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Term
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Definition
- Surgical resection: 70% of CRCs are resectable for cure at presentation
- Chemotherapy: Fluorouracil and Leucovorin
- Radiation: For stages II and III |
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Term
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Definition
- follow up every 3-6 months for first 3 years and then at decreased frequency for next 2 years
- Colonscopy every year for first 2 years, and then every 3 years
- Baseline CEA level every 3 to 6 months for first 5 years |
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Term
| Non-Neoplastic Mucosal Polyps: |
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Definition
He Made Jello Pudding Interesting.
- Hyperplastic polyp (including serrated)
- Mucosal polyp (normal mucosa in a polypoid configuration)
- Juvenile polyp (retention polyp)
- Peutz-Jeghers polyp
- Inflammatory polyp |
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Term
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Definition
CPLLCMO
- Colitis cystica profunda
- Pneumatosis cystoides coli
- Lymphoid polyps (benign and malignant)
- Lipoma
- Carcinoid
- Metastatic neoplasms
- Other rare lesions |
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Term
| Screening blood test for children with FAP and why? |
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Definition
- alpha-fetoprotein
- used in kids with FAP up until age 5 to screen for hepatoblastoma |
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Term
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Definition
- Endoscopic surveillance
- Flexible sigmoid every 1-2 years starting b/w ages 10 and 12 to document onset of polyposis
- Sigmoidoscopic surveillance and ablation of polyps every 3-6 months in those who have had had colonic resection
- Screening family members of FAP patients starting at age 12 |
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