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GI Self Study LI -6
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37
Accounting
Pre-School
10/11/2012

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Term
Cause is unknown but a few theories suggest that a persistent infectious process may incite chronic granulomatous vasculitis
Definition
Idiopathic inflammatory Bowel Disease
Term
Might account for disease development in idiopathic inflammatory bowel disease
Definition
Abnormal host reactivity
Term
The clinical and pathological manifestations of IIBD ultimately are the result of _____whose products can injure cells and tissues
Definition
Activation of inflammatory cells
Term
a relapsing, inflammatory, granulomatous disease that may affect any portion of the GI tract from the esophagus to anus but most often involves the SI and colon
Definition
Crohn Disease
Term
A delimited and transmural involvement of the bowel by an inflammatory process with mucosal damage. Pressence of non-ceseating granulomas and fistulas
Definition
Crohn Disease
Term
Crohn: a thin stream of barium passing through the diseased segment
Definition
String Sign
Term
Crohn: sharp demarcation between diseased bowel and adjacent uninvolved segments
Definition
Skip lesions
Term
Crohn: mucosal ulcers that coalesce into long serpentice ulcers
Definition
Linear ulcers also superficial ulcers present
Term
crohn: present in all tissue layers of diseased and uninvolved segments of bowel
Definition
Noncaseating granulomas
Term
Clinical onset of crohns
Definition
Attacks of diarrhea, fever, abdominal pain precipitated by physical and emotional stress
Term
Clinical features of chronic disease of crohns
Definition
Fibrosing strictures, protein loss, pernicious anemia, Steatorrhea, INCREASED INCIDENCE OF CANCER OF THE GI TRACT
Term
Extraintestinal manifestations of crohns (3)
Definition
1. migratory polyarthritis
2. Sacroilitis
3. Ankylosing spondylitis
Term
A relapsing, inflammatory, non-granulomatous disease limited to the colon, with extraintestinal inflammatory manifestations
Definition
Ulcerative Colitis
Term
Ulcerative colitis is limited to the colon affecting what layers
Definition
Mucosa and submucosa
Term
Ulcerative colitis: created by isolated islands of regenerating mucosa that bulge upward
Definition
PSeudopolyps
Term
UC: formed by collection of neutrophils in crypt lumens
Definition
Crypt abscesses
Term
When UC extends into the submucosa
Definition
Mucosal ulceration
Term
When UC is present in inflammed or uninflammed mucosa
Definition
Epithelial dysplasia
Term
A relapsing disorder marked by attacks of bloody mucoid diarrhea for days, weeks, months, (asymptomatic periods), Flare-ups with stress. Perforation and toxic megacolon. LONG TERM COMPLICATION IS GASTROINTESTINAL CANCER
Definition
Ulcerative Colitis
Term
A non-neoplastic intestinal lesion of vascular dilation and malformation. In cecum or right colon. 60 year olds.
Definition
Angiodysplasia (vascular ectasia)
Term
A blind pouch of ailmentary tract, found in colonic mucosa and submucosa. Most common on the left side of the colon (sigmoid) 50% of adults over 60
Definition
Diverticular Disease
Term
Pathogenesis is a focal weakness in the colonic wall with increased intraluminal pressure
Definition
Diverticular Disease
Term
Variceal Dilatation of anal and perianal venous plexi
Definition
Hemorrhoids
Term
Involve superior hemorrhoidal plexus above anorectal line (painless)
Definition
Internal Hemorrhoids
Term
Involve inferior hemorrhoidal plexus below anorectal line
Definition
External Hemorrhoids
Term
Continued secreation of mucinous fluid in the obstructed _________leads to increased intraluminal pressure, collapse of draining veins, ischemia, inflammation, and bacterial proliferation
Definition
Appendix during acute appendicitis
Term
Periumbilicl pain, localized to the right lower quadrant, nausea, vomiting, abdominal tenderness. elevated white count
Definition
Acute Appendicitis
Term
The most common tumor of the appendix
Definition
Carcinoid
Term
A tumorous mass that protrudes in to the lumen of bowel
Definition
Polyp
Term
Formed as a result of abdominal mucosal maturation, inflammation, or architecture
Definition
Hyperplastic polyps
Term
Epithelial proliferation, exhibit dysplasia and are precursors to carcinoma
Definition
Adenomatous polyps
Term
Peak 60-79, us with highest death rates...higher incidence in low fiber, high carbs, red meat, to many calories
Definition
Colorectal Cancer, poor prognosis
22% CECUM
55% sigmoid
Term
Tumors of the distal portion of colon grow as
Definition
Annular, encircling, napkin ring appearance
Term
Tumors in the proximal portions of the colon tend to grow as
Definition
polypoid, exophytic
Term
Iron Deficiency in older men means
Definition
Gastrointestinal cancer until proven otherwise
Term
Anal canal carcinoma has what differentiation
Definition
Basaloid (proliferative cells derived from the basal layer of stratified squamous epithelium)
Term
Pure squamous cell carcinomas of the anal canal are closely associated with what chronic infection
Definition
HPV
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