Term
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Definition
| Gets treated with Amox/clarithromycin, Metro, tetracycline plus PPI or anti-secretory agents like bismuth. |
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Term
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Definition
MOA: Inhibits H/K ATPase on parietal cells,lowers acid .
Indicated for: acid secretions causing GERD, Ulcers, Hypersecretory states.
A/E: Constipation |
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Term
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Definition
Cimetidine
Ranitidine
Famotidine |
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Term
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Definition
MOA: H2 receptor inhibition.
Indications: duodenal/gastric ulcers, GERD, hypersecretory states
A/E: diarrhea, dizziness, rash, HA, confusion, somnolence, decreased libido, gynecomastia, hepatotoxic, nephrotoxic. |
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Term
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Definition
MOA: H2 receptor inhibition.
Indications: duodenal/gastric ulcers, GERD, hypersecretory states
A/E: depression of CNS, decreased libido |
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Term
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Definition
MOA: H2 receptor inhibition.
Indications: duodenal/gastric ulcers, GERD, hypersecretory states
A/E: CNS depression and decreased libido. |
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Term
Antacids:
Calcium carbonate
Aluminum salts
MG Salts
Sodium citrate (pre-op antacid) |
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Definition
MOA: neutralizes acid (H+) and decreases mucosal irritation.
A/E:GI side effects |
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Term
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Definition
MOA: when exposed to GI H+--> coats the stomach.
Indications: prophylaxis/tx of duodenal ulcers.
A/E: constipation |
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Term
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Definition
MOA: increases bicarbonate, mucin and decreased H+ secretion.
Indications: Prevention of ulcers caused by ASA/NSAIDs.
A/E: abortifacient (increases uterine contractions), N/D/Gas, Abdominal Pain |
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Term
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Definition
MOA: increased gastric emptying rate
Indications: Gastroparesis, reflux esophagitis, hypersecretory states.
A/E: EPS b/c it antagonizaes DA. Dizzy, constipated, drowsy, depressed. |
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Term
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Definition
Opiates: Loperamide
Adsorbents: bismuth, kaolin/pectin, cholestyramine.
Others: Anti-ACh drugs, Steroids, Abx. |
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Term
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Definition
Loperamide
MOA: agonist of opioid receptors in GI, doesn't cross the BBB
A/E: constipation |
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Term
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Definition
Bisthmuth: moa is to absorb toxins, indicated for diarrhea and prophylaxis of travelers diarrhea. A/E: constipation.
Kaolin/Pectin: absorbs toxins, indicated for diarrhea, A/E: binds and increases K+ loss which can lead to arrhythmias, absorb drugs and nutrients.
Cholestyramine: for absorbtion of bile salts and toxin from C. difficile (pt's with bile salt caused or c. diff caused diarrhea). a/e constipation |
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Term
| Anti ACh drugs for Diarrhea |
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Definition
MOA: inhibit peristalsis
A/E Constipation
Drug like Benadryl, Dramamine, atropine. |
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Term
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Definition
| Indicated for UC, Chrohns, Infectious inflammatory bowel dz |
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Term
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Definition
Bulk Forming laxatives
Laxative Stimulants
Others |
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Term
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Definition
Psyllium, Methylcellulose, Ca+ PO4- Carbophil
MOA: non-digested, pulls more H20 into feces which increases bulk.
A/E: flatulence, impaction. |
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Term
| Stimulants for constipation |
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Definition
Laxatives: Bisacodyl
MOA: stool softener, increase H20 and Electrolytes in feces, increase GI motility.
A/E: severe diarrhea |
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Term
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Definition
Lubricates feces and doesn't absorb H20
A/E: anal leakage, irritation, decreased nutrient absorbtion. |
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Term
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Definition
| MOA: draws H20 to colon, hyperosmolar; given rectally. |
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Term
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Definition
| MOA poor absorption, colon brings H20 to lumen |
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Term
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Definition
| MOA: increased penetration of H20 and fat into feces. |
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