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GI Pathophysiology - Stomach
Pathology of the GI tract
28
Physiology
Undergraduate 3
12/12/2013

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Cards

Term
Name the 3 regions of the stomach
Definition
1. Fundus
2. Body
3. Antrum
Term
What are the secretory differences between the body and antrum of stomach?
Definition
- Body secretes mucous, HCL, pepsin
- Antrum secretes mucous, pepsin and gastrin
Term
What are the 3 functions of the stomach?
Definition
1. Secretion of acid, mucous and proenzymes
2. Mixing
3. Storage of bolus
Term
(T/F) There is evidence of both CNS and GI involvement during the vomiting reflex
Definition
True
Term
List two health risks associated with vomiting?
Definition
- Aspiration
- Electrolyte imbalance
Term
List the 4 steps to the vomiting reflex?
Definition
1. Glottis closes
2. LES relaxes
3. Reverse peristaltic waves
4. Abdominal contraction
Term
List 5 stimuli for vomiting?
Definition
- GIT distention
- GIT irritation
- Intracranial pressure/motion sickness
- Drugs
- Noxious perceptions
Term
What are noxious perceptions?
Definition
The perception of a potentially tissue damaging event, or an event that actually occurs
Term
(T/F) Gastritis can be life threatening
Definition
True
Term
What is gastritis?
Definition
Inflammation of the stomach mucosa
Term
What does chronic gastritis lead to? Is this pathology limited to the stomach?
Definition
Ulcers; no, can have duodenal ulcers as well
Term
(T/F) Helicobacter pylori has not been shown to be linked with gastritis
Definition
False, it has
Term
What does helicobacter pylori presence in the stomach usually cause? How can this lead to ulceration?
Definition
Gastritis - inflammation. If infection is not taken care of, chronic inflammation usually leads to ulceration
Term
What percentage of patients with ulcers have an H-Pylori infection?
Definition
70-98%
Term
What is dumping syndrome? Does it have a well defined etiology?
Definition
Repeated gastric emptying; no, it is considered idiopathic
Term
Although dumping syndrome is considered idiopathic, what is it often linked with?
Definition
Reduction in stomach size/volume after bariatric surgery
Term
What is bariatric surgery?
Definition
A operation to reduce the capacity of the stomach
Term
What characterizes a malabsorptive bariatric operation?
Definition
SI is bypassed as well.
Term
(T/F) The stomach is often completely removed during bariatric surgery
Definition
False
Term
Name the 3 bariatric strategies. Which is most common, and what is done in each case?
Definition
1. Roux-en-Y: stomach is bypassed (or a new, smaller stomach is added)
2. Adjustable gastric banding (most common): adjustable band is added to stomach that can control stomach size
3. Sleeve gastrectomy: much of stomach is walled off, and a small opening is left for food to enter the stomach
Term
(T/F) Both publicly funded, and privately paid bariatric surgies occur in Canada?
Definition
True
Term
List the characteristics of publicly paid surgeries
Definition
- Longer wait time
- R-en-Y usually used (Much better for treating co-morbities; major surjery therefore more risks
Term
List the characteristics of privately paid surgeries
Definition
- More expensive
- Shorter wait
- AGB is most common (Safer and faster)
Term
Why is bariatric surgery considered an effective treatment for TII diabetes?
Definition
Because it results the reduction of adverse outcomes of obesity and an increased lifespan
Term
What is gastroparesis?
Definition
Delayed emptying of the stomach
Term
Why is it common in diabetes?
Definition
The pathologies that affect the nervous system affect the ENS as well, and this impaired function results in delayed emptying
Term
What can cause the stomach to fail to empty?
Definition
- Pyloric stenosis
- Defective spincherter in neonate
- ENS abnormality causes no inhibitory innervation, therefore the pyloric sphincter is always shut
Term
What are 3 functional problems that can occur in the stomach?
Definition
1. Dumping syndrome
2. Gastroparesis - Delayed emptying
3. Failure to empty
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