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GI/Nutrition Agents
Study Guide
27
Pharmacology
Undergraduate 3
11/17/2013

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Term
antiacids
Definition
reduce pain associated with acid-related disorders
raises gastric pH 1 point
contains salts of magnesium, aluminum, calcium, and/or sodium/sodium bicarbonate
Term
patient teaching/side effects for antacids
Definition
constipation, diarrhea, kidney stones, gas
watch drug interactions, administer other meds 1-2 hours later so that the altered pH of stomach doens't affect them, administer with 8 ou of water, may mask symptoms of serious underlying diseases
Term
H2 antagonists
Definition
reduce acid secretion
OTC (pepsid, zantac)
block H2 receptor of acid producing parietal cell
increase pH of stomach
Term
proton pump inhibitors
Definition
parietal cells release potsitive H2 ions during HCl production-proton pump
irreversibly bind to H+/K+ ATPase enzyme
prevents movement of H2 ions from parietal cell into stomach
forces parietal cell to synthesize new H+/K+ ATPase
Term
mucosal protection
Definition
sucralfate- cytoprotective drug
for stress ulcers, peptic ulcer disease
Term
GI prostaglandins
Definition
Misoprostol
cytoprotective activity, enhance local production of mucus or bicarbonate, local cell regenation
Term
GI stimulant
Definition
antiflatulent
Term
laxative administration and patient teaching
Definition
swalled whole with water
healthy high fiber diet with increased fluid intake
don't use long term - results in dependency, decreased bowel tone
Term
antiemetics and antinausea drugs
Definition
anticholinergic, antihistamines, antidopaminergic, prokinetic, serotonin blockers, tetrahydrocannabinoids

they block one of the vomiting pathways: PO or IM
anticholinergic SE means parasympathetic nerve fibers are blocked
Term
A deficiency
Definition
hyperkeratosis of skin, night blindness
Term
D deficiency
Definition
rickets, tetany, osteomalacia
Term
K deficiency
Definition
impaired clotting
Term
B deficiency:
Definition
beriberi (disease causing inflammation of the nerves and heart failure), brain lesions, polyneuropathy of peripheral nerves, serous effusions, cardiac anatomic changes, wernicke's encephalopathy
Term
B2 deficiency
Definition
cutaneous, oral, and corneal changes (cheilosis, (chapped/fissured lips), seborrheic dermatitis, keratitis
Term
B3 deficiency
Definition
pellagra (niacin deficiency), psychotic symptoms, neurasthenic syndrome (fatigue, headache, and irritability, associated chiefly with emotional disturbance.), crusting, erythema, inflammation, diarrhea,
Term
B6 deficiency
Definition
pyridoxine, sideroblastic anemia, neurologic disturbanes, seborrheic dermatitis, cheilosis, glossitis, stomatitis, epileptiform convultsions, hypochromic microcytic anemia
Term
B12 deficiency
Definition
cyanocobalmin
pernicious anemia
neuro damage
megaloblastic anemia
Term
C deficiency
Definition
scurvy
gingivitis and bleeding gums
loss of teeth
anemia
subcutaneous hemorrhage
bone lesions
delayed healing of soft tissues and bones
Term
calcium deficiency
Definition
hypocalcemia: infantile rickets, osteomalacia, osteoporosis
Term
hypomagnesemia
Definition
needed for nerve physiology and muscle contraction
Term
phosphorous
Definition
required for synthesis of nucleic acids, ADP, AMP, and ATP
Term
Zinc
Definition
needed for normal tissue growth and repair, especially in wound healing, essential in metabolic reactions of proteins and carbohydrates
Term
enteral tube dehydration
Definition
happens because of associated diarrhea or vomiting
flushes are only used before or after a feeding
ensure complete nutritional assessment, check tube placement, flush tubing, monitor patient toleration, start feedings slowly, monitor for lactose intolerance and monitor blood glucose
Term
Iron supplements
Definition
IM with Z track into vastus lateralis
IV undiluted, slow
PO
don't double dose, stools may be dark green or black
Term
erythropoietin
Definition
protein hormone produced by kidney that stimulates production of RBCs used to treat anemia
given 3x/week then decreased as needed
administered SQ or IV
Term
emetics
Definition
given in case of overdose, poisoning, or exposure to allergens to induce vomiting
teach not to take with alcohol, to stay hydrated, may come with stomach cramps
Term
hyperalimentation
Definition
total parenteral nutrition
provides patients who need more nutrients than present oral intake can provide
indicated for procedures that restrict oral feedings, anorexia caused by chemotherapy or radiation treatments, GI illnesses, postsurgical patients, when oral nurtition will not be started for more than 5 days
administered IV,
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