Term
| IBD most commonly refers to: |
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Definition
| Ulcerative colitis & Crohn's Dz |
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Term
| 4 major risk factors for IBD: |
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Definition
1. FHx; 20-25% have close family member c IBD & if sibling then 10x greater risk
2. american jews of european decent are 4-5x the prevalence of the general pop
3. smoking 2x risk
4. northern states>southern states |
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Term
| inflammatory condition that involves the mucosal surface of the colon |
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Definition
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Term
| 5 terms that describe UC location of involvement: |
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Definition
| 1. U proctitis 2. distal colitis 3. left sided colitis 4. extensive colitis 5. pancolitis |
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Term
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Definition
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Term
| mild UC is typically confined to: |
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Definition
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Term
|
Definition
1. bloody diarrhea/ possible anemia
2. mucus
3. LLQ cramps relieved c defication
4. urgency
5. periods of constipation |
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Term
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Definition
| more than the distal colon, extending at least to the splenic flexure |
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Term
| inflammation involving the mucosa & muscle layers of the colon resulting in impaired mobility, dilation, |
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Definition
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Term
| colonoscopy recomendations for UC: |
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Definition
| every 1-2yrs, 8yrs after dx |
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Term
| 6 extraintestinal complications of IBD: |
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Definition
1. uveitis/scleritis
2. erythema nodosum/pyoderma gangrenosum
3. peripheral arthritis
4. ankylosing spondylitis
5. lung dz
6. venous/arterial thromboembolism |
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Term
|
Definition
1. 5-Aminosalicylic Acid
2. corticosteroids
3. immunomodulating drugs
4. biologic therapies |
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Term
| tx of choice for distal colitis: |
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Definition
| topical or enema mesalamine (5-ASA) |
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Term
| transmural inflammation of Crohn's often leads to: |
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Definition
| fibrosis and obstructions |
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Term
| 1/3 of CD pts have this presentation which separates CD from UC: |
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Definition
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Term
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Definition
1. low grade fvr
2. malaise
3. wt loss
4. diarrhea (bloody or non-bloody)
5. urgency
6. RLQ tenderness/mass (inflammed intestine) |
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Term
| in CD what may lead to narrowing of the small bowel & obstruction? |
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Definition
1. inflammation
2. spasm
3. fibrotic stenosis |
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Term
| 4 conditions of perianal dz: |
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Definition
1. skin tags
2. fisures
3. abcesses
4. fistulas (epi to epi) |
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Term
| 5 extraintestinal conditions assoc w CD: |
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Definition
1. arthralgias/arthritis
2. uveitis
3. aphthous ulcers
4. gallstones
5. nephrolithiasis |
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Term
| linear and discontinuous "skip lesions" with normal tissue btwn ulcers is seen on colonoscopy of: |
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Definition
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Term
| key word: cobblestone on barium enema |
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Definition
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Term
| useful in identifying fistulas, ulcerations & strictures: |
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Definition
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Term
| key differences btwn UC & CD: |
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Definition
UC: colon only, mucosal layer, continuous lesions, more assoc w rectal bleeding
CD: can include entire GI, transmural, patchy skipping ulcers, perianal dz |
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